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    MRTFA myocardin related transcription factor A [ Homo sapiens (human) ]

    Gene ID: 57591, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MRTF-A/SRF signaling suppresses invasion of oral squamous cell carcinoma.

    MRTF-A/SRF signaling suppresses invasion of oral squamous cell carcinoma.
    Yang D, Yang D, He Y, Liu J, Song Y, Zhou Y, Jiang L, Zeng X, Xu X, Xu H, Li J, Dan H.

    09/24/2024
    INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10.

    INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10.
    Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X., Free PMC Article

    07/19/2023
    Role of CRP2-MRTF interaction in functions of myofibroblasts.

    Role of CRP2-MRTF interaction in functions of myofibroblasts.
    Hayashi K, Horoiwa S, Mori K, Miyata H, Labios RJ, Morita T, Kobayashi Y, Yamashiro C, Higashijima F, Yoshimoto T, Kimura K, Nakagawa Y., Free PMC Article

    05/17/2023
    SRF/MRTF-A and liver cirrhosis: Pathologic associations.

    SRF/MRTF-A and liver cirrhosis: Pathologic associations.
    Al-Hetty HRAK, Ismaeel GL, Mohammad WT, Toama MA, Kandeel M, Saleh MM, Turki Jalil A.

    03/1/2023
    MBNL1 and MRTF-A form a positive feedback loop in regulating the migration of esophageal cancer cells.

    MBNL1 and MRTF-A form a positive feedback loop in regulating the migration of esophageal cancer cells.
    Liang C, Chang Z, Luo Y, Xu Y, Chen A, Zhang T.

    10/15/2022
    The prognostic value of MKL1 in predicting breast cancer immune infiltrates and chemosensitivity.

    The prognostic value of MKL1 in predicting breast cancer immune infiltrates and chemosensitivity.
    Hua Y, Yang M., Free PMC Article

    06/11/2022
    MiR-17-5p and MKL-1 modulate stem cell characteristics of gastric cancer cells.

    MiR-17-5p and MKL-1 modulate stem cell characteristics of gastric cancer cells.
    Dai ZT, Xiang Y, Duan YY, Wang J, Li JP, Zhang HM, Cheng C, Wang Q, Zhang TC, Liao XH., Free PMC Article

    03/26/2022
    Oxidative Stress Enhances the TGF-beta2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition.

    Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition.
    Sobierajska K, Wawro ME, Niewiarowska J., Free PMC Article

    03/12/2022
    MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-kappaB signaling.

    MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling.
    Liu Z, Sun J, Li C, Xu L, Liu J., Free PMC Article

    02/12/2022
    Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERalpha nuclear/genomic to extra-nuclear/non genomic actions.

    Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERα nuclear/genomic to extra-nuclear/non genomic actions.
    Jehanno C, Percevault F, Boujrad N, Le Goff P, Fontaine C, Arnal JF, Primig M, Pakdel F, Michel D, Métivier R, Flouriot G.

    12/11/2021
    MRTF-A regulates Ca(2+) release through CACNA1S.

    MRTF-A regulates Ca(2+) release through CACNA1S.
    Liang C, Xu Y, Peng Z, Luo Y, Zhang T.

    12/4/2021
    MRTFA overexpression promotes conversion of human coronary artery smooth muscle cells into lipid-laden foam cells.

    MRTFA overexpression promotes conversion of human coronary artery smooth muscle cells into lipid-laden foam cells.
    Alajbegovic A, Holmberg J, Daoud F, Rippe C, Kalliokoski G, Ekman M, Daudi S, Ragnarsson S, Swärd K, Albinsson S.

    11/27/2021
    MKL1-induced lncRNA SNHG18 drives the growth and metastasis of non-small cell lung cancer via the miR-211-5p/BRD4 axis.

    MKL1-induced lncRNA SNHG18 drives the growth and metastasis of non-small cell lung cancer via the miR-211-5p/BRD4 axis.
    Fan H, Yuan J, Li Y, Jia Y, Li J, Wang X, Li X., Free PMC Article

    10/9/2021
    MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function.

    MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function.
    Xiang Y, Wang J, Li JP, Guo W, Huang F, Zhang HM, Li HH, Dai ZT, Zhang ZJ, Li H, Bao LY, Gu CJ, Chen K, Zhang TC, Liao XH., Free PMC Article

    08/14/2021
    MRTFA: A critical protein in normal and malignant hematopoiesis and beyond.

    MRTFA: A critical protein in normal and malignant hematopoiesis and beyond.
    Reed F, Larsuel ST, Mayday MY, Scanlon V, Krause DS., Free PMC Article

    07/31/2021
    MRTF: Basic Biology and Role in Kidney Disease.

    MRTF: Basic Biology and Role in Kidney Disease.
    Miranda MZ, Lichner Z, Szászi K, Kapus A., Free PMC Article

    07/17/2021
    MKL1/miR-5100/CAAP1 loop regulates autophagy and apoptosis in gastric cancer cells.

    MKL1/miR-5100/CAAP1 loop regulates autophagy and apoptosis in gastric cancer cells.
    Zhang HM, Li H, Wang GX, Wang J, Xiang Y, Huang Y, Shen C, Dai ZT, Li JP, Zhang TC, Liao XH., Free PMC Article

    05/29/2021
    ICAM-1 and MKL-1 polymorphisms impose considerable impacts on coronary heart disease occurrence.

    ICAM-1 and MKL-1 polymorphisms impose considerable impacts on coronary heart disease occurrence.
    Wu C, Huang C., Free PMC Article

    05/8/2021
    A hypothesis for insulin resistance in primary human adipocytes involving MRTF-A and suppression of PPARgamma.

    A hypothesis for insulin resistance in primary human adipocytes involving MRTF-A and suppression of PPARγ.
    Hansson B, Schumacher S, Fryklund C, Morén B, Björkqvist M, Swärd K, Stenkula KG.

    03/20/2021
    The Role of CADM1 and MAL Promoter Methylation in Inflammation and Cervical Intraepithelial Neoplasia.

    The Role of CADM1 and MAL Promoter Methylation in Inflammation and Cervical Intraepithelial Neoplasia.
    Holubekova V, Mersakova S, Grendar M, Snahnicanova Z, Kudela E, Kalman M, Lasabova Z, Danko J, Zubor P.

    03/6/2021
    MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization.

    MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization.
    Sprenkeler EGG, Henriet SSV, Tool ATJ, Kreft IC, van der Bijl I, Aarts CEM, van Houdt M, Verkuijlen PJJH, van Aerde K, Jaspers G, van Heijst A, Koole W, Gardeitchik T, Geissler J, de Boer M, Tol S, Bruggeman CW, van Alphen FPJ, Verhagen HJMP, van den Akker E, Janssen H, van Bruggen R, van den Berg TK, Liem KD, Kuijpers TW.

    02/13/2021
    Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts.

    Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts.
    Holstein I, Singh AK, Pohl F, Misiak D, Braun J, Leitner L, Hüttelmaier S, Posern G., Free PMC Article

    10/31/2020
    Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells.

    Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells.
    Yang Y, Li Z, Guo J, Xu Y.

    10/31/2020
    Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A.

    Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A.
    Shao J, Xu H, Wu X, Xu Y.

    10/24/2020
    Nuclear translocation of MKL1 suppresses estrogen-mediated control of gene expression.

    Nuclear accumulation of MKL1 in luminal breast cancer cells impairs genomic activity of ERα and is associated with endocrine resistance.
    Jehanno C, Fernandez-Calero T, Habauzit D, Avner S, Percevault F, Jullion E, Le Goff P, Coissieux MM, Muenst S, Marin M, Michel D, Métivier R, Flouriot G.

    07/18/2020
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