| [Characteristic Analysis of Adult Acute Myeloid Leukemia Patients with PTPN11 Gene Mutation]. | [Characteristic Analysis of Adult Acute Myeloid Leukemia Patients with PTPN11 Gene Mutation].
Sheng L, Liu YJ, Zhou JF, Chao HY, Hua HY, Zhou X, Zhao XH. | 10/7/2024 |
| MEST promotes immune escape in gastric cancer by downregulating MHCI expression via SHP2. | MEST promotes immune escape in gastric cancer by downregulating MHCI expression via SHP2.
Huang M, Zhang F, Zhu Y, Zeng H, Li S. | 08/30/2024 |
| SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis. | SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.
Chouhan S, Sridaran D, Weimholt C, Luo J, Li T, Hodgson MC, Santos LN, Le Sommer S, Fang B, Koomen JM, Seeliger M, Qu CK, Yart A, Kontaridis MI, Mahajan K, Mahajan NP., Free PMC Article | 07/26/2024 |
| MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells. | MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells.
Perrin S, Protic S, Bretegnier V, Laurendeau I, de Lageneste OD, Panara N, Ruckebusch O, Luka M, Masson C, Maillard T, Coulpier F, Pannier S, Wicart P, Hadj-Rabia S, Radomska KJ, Zarhrate M, Ménager M, Vidaud D, Topilko P, Parfait B, Colnot C. | 07/4/2024 |
| Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-kappaB- Dependent Inflammation. | Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Han X, Wei J, Zheng R, Tu Y, Wang M, Chen L, Xu Z, Zheng L, Zheng C, Shi Q, Ying H, Liang G. | 05/9/2024 |
| SHP2 regulates GluA2 tyrosine phosphorylation required for AMPA receptor endocytosis and mGluR-LTD. | SHP2 regulates GluA2 tyrosine phosphorylation required for AMPA receptor endocytosis and mGluR-LTD.
Lee S, Kim J, Ryu HH, Jang H, Lee D, Lee S, Song JM, Lee YS, Suh YH., Free PMC Article | 05/3/2024 |
| Spectrum of Mutations in PTPN11 in Russian Cohort. | Spectrum of Mutations in PTPN11 in Russian Cohort.
Orlova A, Guseva D, Demina N, Polyakov A, Ryzhkova O., Free PMC Article | 04/1/2024 |
| Clinical Variability in a Family with Noonan Syndrome with a Homozygous PTPN11 Gene Variant in Two Individuals. | Clinical Variability in a Family with Noonan Syndrome with a Homozygous PTPN11 Gene Variant in Two Individuals.
Yıldırım R, Unal E, Özalkak Ş, Akalın A, Aykut A, Yılmaz N., Free PMC Article | 03/12/2024 |
| Mutations in PTPN11 could lead to a congenital myasthenic syndrome phenotype: a Noonan syndrome case series. | Mutations in PTPN11 could lead to a congenital myasthenic syndrome phenotype: a Noonan syndrome case series.
Pugliese A, Della Marina A, de Paula Estephan E, Zanoteli E, Roos A, Schara-Schmidt U, Hentschel A, Azuma Y, Töpf A, Thompson R, Polavarapu K, Lochmüller H. | 02/28/2024 |
| Plasma-derived exosomal protein SHP2 deficiency induces neutrophil hyperactivation in Behcet's uveitis. | Plasma-derived exosomal protein SHP2 deficiency induces neutrophil hyperactivation in Behcet's uveitis.
Cai J, Wang Q, Tan S, Jiang Q, Liu R, Su G, Yi S, Yang P. | 02/22/2024 |
| High expression of SHP2 predicts a promising prognosis in colorectal cancer. | High expression of SHP2 predicts a promising prognosis in colorectal cancer.
Liu X, Li M, Chen L, Wen F, Zheng S, Ge W. | 02/21/2024 |
| Single Ion Pair Is Essential for Stabilizing SHP2's Open Conformation. | Single Ion Pair Is Essential for Stabilizing SHP2's Open Conformation.
Kim SH, Bulos ML, Adams JA, Yun BK, Bishop AC. | 02/8/2024 |
| M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages. | M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages.
Zhang S, Ren D, Hou H, Yao L, Yuan H., Free PMC Article | 01/30/2024 |
| Synergistic effects of BTN3A1, SHP2, CD274, and STAT3 gene polymorphisms on the risk of systemic lupus erythematosus: a multifactorial dimensional reduction analysis. | Synergistic effects of BTN3A1, SHP2, CD274, and STAT3 gene polymorphisms on the risk of systemic lupus erythematosus: a multifactorial dimensional reduction analysis.
Tang YY, Xu WD, Fu L, Liu XY, Huang AF. | 01/15/2024 |
| Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization. | Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization.
Zhou P, Ouyang L, Jiang T, Tian Y, Deng W, Wang H, Kong S, Lu Z. | 01/9/2024 |
| The clinical features and prognostic implications of PTPN11 mutation in adult patients with acute myeloid leukemia in China. | The clinical features and prognostic implications of PTPN11 mutation in adult patients with acute myeloid leukemia in China.
Yang J, Zhao L, Wu Y, Niu T, Gong Y, Chen X, Huang X, Liu J, Dai Y, Ma H., Free PMC Article | 12/27/2023 |
| Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia. | Fgf2 and Ptpn11 play a role in cerebral injury caused by sevoflurane anesthesia.
Zhang L, Xu L., Free PMC Article | 11/18/2023 |
| Relationship between SHP2 gene polymorphisms and systemic lupus erythematosus risk. | Relationship between SHP2 gene polymorphisms and systemic lupus erythematosus risk.
Li R, Zhou L, Yang C, Xu WD, Huang AF. | 10/30/2023 |
| Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia. | Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia.
Pasupuleti SK, Chao K, Ramdas B, Kanumuri R, Palam LR, Liu S, Wan J, Annesley C, Loh ML, Stieglitz E, Burke MJ, Kapur R., Free PMC Article | 10/28/2023 |
| PTPN11 variant may be a prognostic indicator of IDH-wildtype glioblastoma in a comprehensive genomic profiling cohort. | PTPN11 variant may be a prognostic indicator of IDH-wildtype glioblastoma in a comprehensive genomic profiling cohort.
Otani R, Ikegami M, Yamada R, Yajima H, Kawamura S, Shimizu S, Tanaka S, Takayanagi S, Takami H, Yamaguchi T. | 08/30/2023 |
| LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection. | LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection.
Li Y, Guo J, Zhang H, Li Z, Ren Y, Jiang Y, Liu X, Hu X., Free PMC Article | 07/24/2023 |
| Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages. | Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages.
Du L, Ji Y, Xin B, Zhang J, Lu LC, Glass CK, Feng GS., Free PMC Article | 06/12/2023 |
| Genetic and phenotypic heterogeneity of multiple lentigines and precise diagnosis in four Chinese families with multiple lentigines. | Genetic and phenotypic heterogeneity of multiple lentigines and precise diagnosis in four Chinese families with multiple lentigines.
Guo K, Liu JW, Zhang R, Wang R, Ma DL, Zhang X. | 06/9/2023 |
| PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma. | PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma.
Polubothu S, Bender N, Muthiah S, Zecchin D, Demetriou C, Martin SB, Malhotra S, Travnickova J, Zeng Z, Böhm M, Barbarot S, Cottrell C, Davies O, Baselga E, Burrows NP, Carmignac V, Diaz JS, Fink C, Haenssle HA, Happle R, Harland M, Majerowski J, Vabres P, Vincent M, Newton-Bishop JA, Bishop DT, Siegel D, Patton EE, Topf M, Rajan N, Drolet B, Kinsler VA., Free PMC Article | 05/23/2023 |
| Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes. | Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.
Hoffmann L, Coras R, Kobow K, López-Rivera JA, Lal D, Leu C, Najm I, Nürnberg P, Herms J, Harter PN, Bien CG, Kalbhenn T, Müller M, Pieper T, Hartlieb T, Kudernatsch M, Hamer H, Brandner S, Rössler K, Blümcke I, Jabari S., Free PMC Article | 05/19/2023 |