| Mutations in ZP4 are associated with abnormal zona pellucida and female infertility. | Mutations in ZP4 are associated with abnormal zona pellucida and female infertility.
Wei X, Li Y, Liu Q, Liu W, Yan X, Zhu X, Zhou D, Tian Y, Zhang F, Li N, Lu Z. | 03/5/2022 |
| Zona Pellucida Proteins, Fibrils, and Matrix. | Zona Pellucida Proteins, Fibrils, and Matrix.
Litscher ES, Wassarman PM. | 06/5/2021 |
| ZP4 gene SNPs rs547984, rs540782, rs693421, rs2499601 are not associated with open-angle glaucoma among ethnic Hans from Sichuan. | [Association of ZP4 gene polymorphism with primary open-angle glaucoma in an ethnic Chinese population from Sichuan province].
Tan Y, Zhang D, Gong B, Zhang X, Jiang L, Lin Y. | 03/30/2019 |
| ZO4 is highly expressed in ovarian tissue in PCOS patients with regular cycle and without hyperandrogenism; in some patients with PCOS and infertility, ZP4 mutation can be found. | Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome.
Meczekalski B, Nawrot R, Nowak W, Czyzyk A, Kedzia H, Gozdzicka-Jozefiak A., Free PMC Article | 06/28/2016 |
| Human ZP4 is not sufficient to support human sperm binding to the zona pellucida in transgenic mice; other zona proteins may be needed for human gamete recognition. | Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice.
Yauger B, Boggs NA, Dean J., Free PMC Article | 06/18/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.
McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL., Free PMC Article | 09/20/2009 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population.
Nakano M, Ikeda Y, Taniguchi T, Yagi T, Fuwa M, Omi N, Tokuda Y, Tanaka M, Yoshii K, Kageyama M, Naruse S, Matsuda A, Mori K, Kinoshita S, Tashiro K., Free PMC Article | 09/16/2009 |
| a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (p<0.005) and ZP4 (p<0.005) was observed in presence of the immune sera | DNA vaccine encoding chimeric protein encompassing epitopes of human ZP3 and ZP4: immunogenicity and characterization of antibodies.
Choudhury S, Ganguly A, Chakrabarti K, Sharma RK, Gupta SK. | 01/21/2010 |
| induces acrosome reactions which are protein kinase-C, protein tyrosine kinase, T-type Ca2+ channels, and extracellular Ca2+ dependent | Effects of native human zona pellucida glycoproteins 3 and 4 on acrosome reaction and zona pellucida binding of human spermatozoa.
Chiu PC, Wong BS, Chung MK, Lam KK, Pang RT, Lee KF, Sumitro SB, Gupta SK, Yeung WS. | 01/21/2010 |
| ZPB induces acrosomal exocytosis through a Gi independent pathway. | Baculovirus-expressed recombinant human zona pellucida glycoprotein-B induces acrosomal exocytosis in capacitated spermatozoa in addition to zona pellucida glycoprotein-C.
Chakravarty S, Suraj K, Gupta SK. | 01/21/2010 |
| Exposure of sperm to ZP proteins promoted acrosomal exocytosis and changed motility patterns. | Biological effects of recombinant human zona pellucida proteins on sperm function.
Caballero-Campo P, Chirinos M, Fan XJ, González-González ME, Galicia-Chavarría M, Larrea F, Gerton GL. | 01/21/2010 |
| Binding sites for recombinant zona pellucida B (ZPB) glycoprotein are located both at the N- and C-terminus of proacrosin | Binding of recombinant human proacrosin/acrosin to zona pellucida (ZP) glycoproteins. I. Studies with recombinant human ZPA, ZPB, and ZPC.
Furlong LI, Harris JD, Vazquez-Levin MH. | 01/21/2010 |