| Clinical significance of low expression of CADM3 in breast cancer and preliminary exploration of related mechanisms. | Clinical significance of low expression of CADM3 in breast cancer and preliminary exploration of related mechanisms.
Ren H, Wang Z, Zhang L, Zhu G, Li F, Chen B., Free PMC Article | 03/27/2024 |
| A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement. | A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement.
Rebelo AP, Cortese A, Abraham A, Eshed-Eisenbach Y, Shner G, Vainshtein A, Buglo E, Camarena V, Gaidosh G, Shiekhattar R, Abreu L, Courel S, Burns DK, Bai Y, Bacon C, Feely SME, Castro D, Peles E, Reilly MM, Shy ME, Zuchner S., Free PMC Article | 09/25/2021 |
| CADM3 expression was increased in retinoblastoma tissues and cells. miR-140-5p inhibited CADM3 expression possibly by targeting the 3'-UTR. | miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3.
Miao X, Wang Z, Chen B, Chen Y, Wang X, Jiang L, Jiang S, Hao K, Zhang W. | 11/10/2018 |
| Nectin-based cell-cell adhesion was formed at the apical side of the junctional adhesion molecule (JAM)-based cell-cell adhesion; cadherin and claudin were recruited to the nectin-3 and JAM-based cell-cell adhesion sites to form AJ- and TJ-like domains. | Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.
Yamada T, Kuramitsu K, Rikitsu E, Kurita S, Ikeda W, Takai Y. | 08/9/2014 |
| NECL1 can inhibit the migration and invasion of glioma cells and induce differentiation. | [Neural adhesion molecule NECL1 inhibits migration, invasion, and potentially induces differentiation of glioma cell].
Yin B, Chen T, Gao J, Yuan JG, Peng XZ. | 11/17/2012 |
| A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S. | 04/26/2012 |
| Findings clearly reveal the structural basis for the cis-dimerization of nectins through the first Ig-like domains. | Crystal Structure of the cis-Dimer of Nectin-1: implications for the architecture of cell-cell junctions.
Narita H, Yamamoto Y, Suzuki M, Miyazaki N, Yoshida A, Kawai K, Iwasaki K, Nakagawa A, Takai Y, Sakisaka T., Free PMC Article | 07/23/2011 |
| A link might exist between NECL1 and the extracellular matrix protein OPN in inhibiting the migration and invasion of U251 glioma ce | Nectin-like molecule 1 inhibits the migration and invasion of U251 glioma cells by regulating the expression of an extracellular matrix protein osteopontin.
Yin B, Li KH, An T, Chen T, Peng XZ. | 08/23/2010 |
| NECL1 may inhibit the proliferation of T98G cells by inducing its apoptosis. | [Effect of NECL1 on the proliferation of T98G glioma cell line].
Gao J, Chen T, Yin B, Gong YH, Qiang BQ, Yuan JG, Peng XZ. | 05/31/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. | 04/7/2010 |
| Nec- 1 suppress the growth and tumorigenic ability of colon cancer cells. | The cell adhesion nectin-like molecules (Necl) 1 and 4 suppress the growth and tumorigenic ability of colon cancer cells.
Raveh S, Gavert N, Spiegel I, Ben-Ze'ev A. | 02/15/2010 |
| suggests that NECL1 may act as a tumor suppressor in glioma and loss of it in glioma may be caused by histone deacetylation | Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site.
Gao J, Chen T, Liu J, Liu W, Hu G, Guo X, Yin B, Gong Y, Zhao J, Qiang B, Yuan J, Peng X. | 01/21/2010 |
| Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW. | 01/28/2009 |
| Expression of entry receptors nectin-1 and HVEM prevent entry of HSV-1 into human conjunctival epithelium. | HVEM and nectin-1 are the major mediators of herpes simplex virus 1 (HSV-1) entry into human conjunctival epithelium.
Akhtar J, Tiwari V, Oh MJ, Kovacs M, Jani A, Kovacs SK, Valyi-Nagy T, Shukla D., Free PMC Article | 01/21/2010 |
| human NECL1 is an N-linked glycoprotein with a single glycosylation site at position N290KS | Nectin-like molecule 1 is a glycoprotein with a single N-glycosylation site at N290KS which influences its adhesion activity.
Gao J, Chen T, Hu G, Gong Y, Qiang B, Yuan J, Peng X. | 01/21/2010 |
| Necl-1 is a neural-tissue-specific Ca2+-independent immunoglobulin-like cell-cell adhesion molecule which potentially has membrane-associated guanylate kinase subfamily member-binding activity and localizes at the non-junctional cell-cell contact sites | Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.
Kakunaga S, Ikeda W, Itoh S, Deguchi-Tawarada M, Ohtsuka T, Mizoguchi A, Takai Y. | 01/21/2010 |
| crystallographic analysis of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule | Crystal structure of the V domain of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule.
Dong X, Xu F, Gong Y, Gao J, Lin P, Chen T, Peng Y, Qiang B, Yuan J, Peng X, Rao Z. | 01/21/2010 |