| By genome-wide transcriptome mining and gonadal microinjections, results identify two G protein-coupled receptor (GPCR)-regulatory circuits: miR430a-Sox9a (SRY-box transcription factor 9a) in the testis and miR218a-Sox9b (SRY-box transcription factor 9b) in the ovary. | Specific miRNA-G Protein-Coupled Receptor Networks Regulate Sox9a/Sox9b Activities to Promote Gonadal Rejuvenation in Zebrafish.
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J. | 07/4/2020 |
| Mutation of the EWS gene modulates Sox9 gene expression essential for chondrocyte differentiation. | Ewing sarcoma ewsa protein regulates chondrogenesis of Meckel's cartilage through modulation of Sox9 in zebrafish.
Merkes C, Turkalo TK, Wilder N, Park H, Wenger LW, Lewin SJ, Azuma M., Free PMC Article | 06/9/2016 |
| Sox9a plays a critical role in statoacoustic ganglia development. | Fgf-signaling-dependent Sox9a and Atoh1a regulate otic neural development in zebrafish.
Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, Zhu Z, Liu D., Free PMC Article | 03/21/2015 |
| Data demonstrated that the sox9 axis signaling that determines testis formation in mammals also induces zebrafish ovary-testis transition, and adds to its conserved role in sex reversal. | Sox9-related signaling controls zebrafish juvenile ovary-testis transformation.
Sun D, Zhang Y, Wang C, Hua X, Zhang XA, Yan J., Free PMC Article | 06/14/2014 |
| these results reveal that coordination of ZNF219L with Sox9a is involved in the regulation of notochord-specific expression of sncgb. | Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish.
Lien HW, Yang CH, Cheng CH, Liao YF, Han YS, Huang CJ. | 05/3/2014 |
| we found that miR-140 is regulated by the cartilage master transcription regulator Sox9 in zebrafish and mammalian cells. | Sox9 is upstream of microRNA-140 in cartilage.
Nakamura Y, He X, Kato H, Wakitani S, Kobayashi T, Watanabe S, Iida A, Tahara H, Warman ML, Watanapokasin R, Postlethwait JH., Free PMC Article | 06/23/2012 |
| FGF-receptor signalling controls the development of both oligodendrocyte progenitors and astroglia through the regulation of sox9, a gliogenic transcription factor the function of which we show to be conserved in the zebrafish hindbrain. | FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9.
Esain V, Postlethwait JH, Charnay P, Ghislain J., Free PMC Article | 02/1/2010 |
| The role of Sox9a in ff1a gene regulation and function was studied using sox9a morpholinos. | Sox9a regulation of ff1a in zebrafish (Danio rerio) suggests an involvement of ff1a in cartilage development.
Koskinen J, Karlsson J, Olsson PE. | 01/21/2010 |
| jef (sox9a) is essential for both morphogenesis of condensations and overt cartilage differentiation | A zebrafish sox9 gene required for cartilage morphogenesis.
Yan YL, Miller CT, Nissen RM, Singer A, Liu D, Kirn A, Draper B, Willoughby J, Morcos PA, Amsterdam A, Chung BC, Westerfield M, Haffter P, Hopkins N, Kimmel C, Postlethwait JH. | 01/21/2010 |
| zebrafish Anti-Mullerian hormone (Amh) is regulated by sox9a, sox9b, and cyp19a1a during gonad development | Characterization and expression pattern of zebrafish Anti-Müllerian hormone (Amh) relative to sox9a, sox9b, and cyp19a1a, during gonad development.
Rodríguez-Marí A, Yan YL, Bremiller RA, Wilson C, Cañestro C, Postlethwait JH. | 01/21/2010 |
| zebrafish sox9a and sox9b have roles in craniofacial and pectoral fin development | A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development.
Yan YL, Willoughby J, Liu D, Crump JG, Wilson C, Miller CT, Singer A, Kimmel C, Westerfield M, Postlethwait JH. | 01/21/2010 |