| Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population. | Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.
Zhang R, Fu Z, Fan H, Tian T, Wu M, Xie C, Huang P, Yu R, Zhang Y, Zhang W, Wang J. | 02/12/2022 |
| Data show that pregnane X receptor/retinoid X receptor PXR/RXR-[alpha], RXR-[beta], or RXR-[gamma] expression was noted in 9 (16.4%), 9 (16.4%), and 10 (18.2%) pancreatic adenocarcinoma cases, respectively. | Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.
Koutsounas I, Giaginis C, Alexandrou P, Zizi-Serbetzoglou A, Patsouris E, Kouraklis G, Theocharis S. | 06/28/2016 |
| RXR interaction is necessary for NPM-RAR-mediated myeloid maturation arrest. | Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
Rush EA, Pollock SL, Abecassis I, Redner RL., Free PMC Article | 02/22/2014 |
| A fatty acid-binding protein 7/RXRbeta pathway enhances survival and proliferation in triple-negative breast cancer. | A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer.
Liu RZ, Graham K, Glubrecht DD, Lai R, Mackey JR, Godbout R. | 01/12/2013 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Genetic variability of RXRB, PPARA, and PPARG in Wegener's granulomatosis.
Wieczorek S, Knaup S, Gross WL, Epplen JT., Free PMC Article | 03/25/2009 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | See all PubMed (4) articlesVitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, Abnet CC, Huang WY, Kibel AS, Crawford ED, Weinstein SJ, Chanock SJ, Schatzkin A, Hayes RB, Prostate, Lung, Colorectal and Ovarian Trial Project Team. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q. Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.
Chang SC, Rashid A, Gao YT, Andreotti G, Shen MC, Wang BS, Han TQ, Zhang BH, Sakoda LC, Leitzmann MF, Chen BE, Rosenberg PS, Chen J, Chanock SJ, Hsing AW. Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.
Vasků V, Bienertová Vasků J, Pávková Goldbergová M, Vasků A, Vasků V, Bienertová Vasků J, Pávková Goldbergová M, Vasků A. | 03/13/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (13) articlesExamination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Dorak MT. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China.
Andreotti G, Menashe I, Chen J, Chang SC, Rashid A, Gao YT, Han TQ, Sakoda LC, Chanock S, Rosenberg PS, Hsing AW. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA. Retinoid X receptor beta polymorphisms do not explain functional differences in vitamins D and A response in Antineutrophil cytoplasmic antibody associated vasculitis patients.
Kälsch AI, Peters A, Buhl B, Breedijk A, Prem K, Schmitt WH, Weiss C, Heeringa P, Kallenberg C, Birck R, Yard BA. Genetic susceptibility to distinct bladder cancer subphenotypes.
Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, EPICURO/Spanish Bladder Cancer Study investigators. PTEN identified as important risk factor of chronic obstructive pulmonary disease.
Hosgood HD 3rd, Menashe I, He X, Chanock S, Lan Q. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, MrOS Research Group. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
Hosgood HD 3rd, Menashe I, Shen M, Yeager M, Yuenger J, Rajaraman P, He X, Chatterjee N, Caporaso NE, Zhu Y, Chanock SJ, Zheng T, Lan Q. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Lu Y, Dollé ME, Imholz S, van 't Slot R, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM. Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes.
van der Slik AR, van den Eng I, Eerligh P, Doxiadis II, Koeleman BP, Roep BO, Giphart MJ. Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.
Feng J, Chen J, Yan J, Jones IR, Craddock N, Cook EH Jr, Goldman D, Heston LL, Sommer SS. Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to alcohol dependence.
Ishiguro H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T, Ishiguro H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T. | 03/13/2008 |
| In healthy elderly men reduction of RXRbeta expression in peripheral blood mononuclear cells might be a common feature of physiological senescence. | Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation.
Brtko J, Rock E, Nezbedova P, Krizanova O, Dvorcakova M, Minet-Quinard R, Farges MC, Ribalta J, Winklhofer-Roob BM, Vasson MP, Macejova D. | 01/21/2010 |
| PPARgamma/retinoid X receptor complex released from activated platelets in microparticles was internalized by a monocytic cell line. | Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.
Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP., Free PMC Article | 01/21/2010 |
| Family studies revealed significant linkage disequilibrium between the RXRB alleles and a number of HLA-DPB1 alleles. | Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor beta haplotypes.
Rajsbaum R, Fici D, Boggs DA, Fraser PA, Flores-Villanueva PO, Awdeh ZL. | 01/21/2010 |
| partial dissociation of TR/retinoid X receptor heterodimer complex from the TRE is involved in the suppression of transcription induced by polychlorinated biphenyls | Polychlorinated biphenyls suppress thyroid hormone receptor-mediated transcription through a novel mechanism.
Miyazaki W, Iwasaki T, Takeshita A, Kuroda Y, Koibuchi N. | 01/21/2010 |
| polymorphism is unrelated to schizophrenia or alcoholism. | Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to alcohol dependence.
Ishiguro H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T, Ishiguro H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T. | 01/21/2010 |
| In the RXRB polymorphism, no genotype TT is observed in patients with psoriasis guttata with a positive personal history of repeated tonsillitis (p(corr) = 0.001). | Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.
Vasků V, Bienertová Vasků J, Pávková Goldbergová M, Vasků A, Vasků V, Bienertová Vasků J, Pávková Goldbergová M, Vasků A. | 01/21/2010 |
| The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer | The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.
Brabender J, Danenberg KD, Metzger R, Schneider PM, Lord RV, Groshen S, Tsao-Wei DD, Park J, Salonga D, Hölscher AH, Danenberg PV. | 01/21/2010 |
| Diminished RXRbeta expression might be related to prostate cancer progression. Because responsiveness to retinoic acid treatments depends on expression of different receptors, it is important to study their expression before therapy. | Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.
Alfaro JM, Fraile B, Lobo MV, Royuela M, Paniagua R, Arenas MI. | 01/21/2010 |
| The retinoid X receptor, beta is expressed widely and can be found in almost every tissue. | Retinoid X receptors: X-ploring their (patho)physiological functions.
Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L. | 01/21/2010 |