| RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID. | RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID.
Voinsky I, Goldenberg-Bogner O, Israel-Elgali I, Volkov H, Puzianowska-Kuźnicka M, Shomron N, Gurwitz D. | 10/31/2024 |
| BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors. | BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors.
Bertran-Alamillo J, Giménez-Capitán A, Román R, Talbot S, Whiteley R, Floc'h N, Martínez-Pérez E, Martin MJ, Smith PD, Sullivan I, Terp MG, Saeh J, Marino-Buslje C, Fabbri G, Guo G, Xu M, Tornador C, Aguilar-Hernández A, Reguart N, Ditzel HJ, Martínez-Bueno A, Nabau-Moretó N, Gascó A, Rosell R, Pease JE, Polanska UM, Travers J, Urosevic J, Molina-Vila MA., Free PMC Article | 09/11/2023 |
| Influence of thyroid hormone in the expression of the marker pro-apoptosis BID, in spite of the predominance of anti-apoptosis activation in intratiroidal lymphocytic infiltration in Hashimoto's thyroiditis. | Influence of thyroid hormone in the expression of the marker pro-apoptosis BID, in spite of the predominance of anti-apoptosis activation in intratiroidal lymphocytic infiltration in Hashimoto's thyroiditis.
Vasconcelos JC, Siqueira IB, Maia FFR, Parisi MCR, Zantut-Wittmann DE. | 03/26/2022 |
| BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. | BCL-2-family protein tBID can act as a BAX-like effector of apoptosis.
Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ., Free PMC Article | 02/19/2022 |
| BID and the alpha-bisabolol-triggered cell death program: converging on mitochondria and lysosomes. | BID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes.
Rigo A, Ferrarini I, Lorenzetto E, Darra E, Liparulo I, Bergamini C, Sissa C, Cavalieri E, Vinante F., Free PMC Article | 09/5/2020 |
| The findings suggest that the cleaved Bid protein acts as an amplifier of apoptotic signaling through mitochondria, thus enhancing the activity of cysteine cathepsins following stefin B degradation. | Menadione-induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation.
Božič J, Bidovec K, Vizovišek M, Dolenc I, Stoka V. | 07/25/2020 |
| Differential roles for FL_BID and t-BID in Burkitt's lymphoma during apoptosis. There is a functional cooperation between BAK and BAX during VT-1-induced apoptosis and, unexpectedly, that activation of caspase-8 and production of t-BID were not mandatory for initiation of the cell death process. | Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt's lymphoma cells.
Debernardi J, Hollville E, Lipinski M, Wiels J, Robert A., Free PMC Article | 03/16/2019 |
| These results identify a role for Bid in homeostatic mitochondrial cristae reorganization, that we link to human cardiac disease. | Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.
Salisbury-Ruf CT, Bertram CC, Vergeade A, Lark DS, Shi Q, Heberling ML, Fortune NL, Okoye GD, Jerome WG, Wells QS, Fessel J, Moslehi J, Chen H, Roberts LJ 2nd, Boutaud O, Gamazon ER, Zinkel SS., Free PMC Article | 03/2/2019 |
| results suggest that histone modifications in the promoter region of miR-500a may be responsible for the increased expression of miR-500a in Hepatocellular carcinoma (HCC), which promotes cancer progression by targeting BID, indicating that miR-500a may be a potential prognostic predictor and therapeutic target for HCC patients. | MicroRNA-500a Promotes the Progression of Hepatocellular Carcinoma by Post-Transcriptionally Targeting BID.
Bao L, Zhang M, Han S, Zhan Y, Guo W, Teng F, Liu F, Guo M, Zhang L, Ding G, Wang Q. | 08/18/2018 |
| The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production. | The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production.
Kim WS, Lee KS, Kim JH, Kim CK, Lee G, Choe J, Won MH, Kim TH, Jeoung D, Lee H, Kim JY, Ae Jeong M, Ha KS, Kwon YG, Kim YM. | 06/2/2018 |
| administration of SMAC or BH3 mimetics following short-term paclitaxel treatment could be an effective therapeutic strategy for TNBC, while only BH3-mimetics could effectively overcome long-term paclitaxel resistance | Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells.
Panayotopoulou EG, Müller AK, Börries M, Busch H, Hu G, Lev S., Free PMC Article | 05/19/2018 |
| caspase-10 was dispensable for enhancement of cisplatin/LA-12 and TRAIL combination-induced cell death and stimulation of Bid cleavage | Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10.
Vondálová Blanářová O, Šafaříková B, Herůdková J, Krkoška M, Tománková S, Kahounová Z, Anděra L, Bouchal J, Kharaishvili G, Král M, Sova P, Kozubík A, Hyršlová Vaculová A., Free PMC Article | 12/30/2017 |
| an oligomeric arrangement of Bid, Bax, and possibly other members of the Bcl-2 family of proteins that form a self-propagating network that permeabilizes the outer-mitochondrial membrane. | Bcl-2 proteins bid and bax form a network to permeabilize the mitochondria at the onset of apoptosis.
Gahl RF, Dwivedi P, Tjandra N., Free PMC Article | 08/5/2017 |
| Combined therapy with Seliciclib((R)) and Belinostat((R)) results in eradication of non-small cell lung cancer via apoptosis induction and BID activation. | A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation.
Ong PS, Wang L, Chia DM, Seah JY, Kong LR, Thuya WL, Chinnathambi A, Lau JY, Wong AL, Yong WP, Yang D, Ho PC, Sethi G, Goh BC. | 07/29/2017 |
| Results from genome-wide DNA methylation, functional network analysis and pyrosequencing, show selective CpG sites (NOS1AP, BID, and GABRB1) differentially methylated in smokers and chronic obstructive pulmonary disease patients compared to nonsmokers. | DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.
Sundar IK, Yin Q, Baier BS, Yan L, Mazur W, Li D, Susiarjo M, Rahman I., Free PMC Article | 04/22/2017 |
| The adenovirus-mediated truncated Bid overexpression induced by the Cre/LoxP system can effectively eliminate CD133+ ovarian cancer stem cells, representing a novel therapeutic strategy for the treatment of ovarian cancer. | Adenovirus-mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells.
Long Q, Yang R, Lu W, Zhu W, Zhou J, Zheng C, Zhou D, Yu L, Wu J. | 04/15/2017 |
| MiR-20a-directed regulation of BID in colorectal cancer. | miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer.
Huang G, Chen X, Cai Y, Wang X, Xing C. | 03/18/2017 |
| the results establish that cleavage by caspase 8 and the subsequent association with the outer mitochondrial membrane are two critical events that activate Bid during death receptor-mediated apoptosis. | Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X., Free PMC Article | 01/28/2017 |
| The results indicate that BID-independent pathways are responsible for FAS-dependent human islet cell death in Type 1 diabetes. | Human islet cells are killed by BID-independent mechanisms in response to FAS ligand.
Joglekar MV, Trivedi PM, Kay TW, Hawthorne WJ, O'Connell PJ, Jenkins AJ, Hardikar AA, Thomas HE. | 12/17/2016 |
| The BID-MTCH2 axis regulates the differentiation/apoptosis of stem cells and mitochondrial metabolism. (Review) | BCL-2 family proteins as regulators of mitochondria metabolism.
Gross A. | 08/20/2016 |
| Data suggest, in models of spatial propagation of mitochondrial permeabilization during apoptosis, there appears to be requirement for cooperative signaling involving truncated-BID and ROS (reactive oxygen species) for efficient/ robust propagation. | An Analysis of the Truncated Bid- and ROS-dependent Spatial Propagation of Mitochondrial Permeabilization Waves during Apoptosis.
Jacob SF, Würstle ML, Delgado ME, Rehm M., Free PMC Article | 08/6/2016 |
| this study emphasizes that the coordinated action of hGzmB-activated p53 and GzmB-cleaved Bid is important for GzmB-induced cell death and for cytotoxic lymphocyte/Natural Killer Cell-mediated killing of target cells. | Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.
Ben Safta T, Ziani L, Favre L, Lamendour L, Gros G, Mami-Chouaib F, Martinvalet D, Chouaib S, Thiery J. | 02/27/2016 |
| Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis. | Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis.
Naghdi S, Várnai P, Hajnóczky G., Free PMC Article | 01/30/2016 |
| Tax confers apoptosis resistance to HTLV-1-infected T cells by suppressing the expression of Bim and Bid. | Tax contributes apoptosis resistance to HTLV-1-infected T cells via suppression of Bid and Bim expression.
Mühleisen A, Giaisi M, Köhler R, Krammer PH, Li-Weber M., Free PMC Article | 09/12/2015 |
| EG also activated the death receptor-dependent pathway of apoptosis by enhancing the expression of caspases-8, -9, and -3 and the Bcl-2 interacting domain (Bid). | Ethyl gallate induces apoptosis of HL-60 cells by promoting the expression of caspases-8, -9, -3, apoptosis-inducing factor and endonuclease G.
Kim WH, Song HO, Choi HJ, Bang HI, Choi DY, Park H., Free PMC Article | 08/22/2015 |