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    SFRP1 secreted frizzled related protein 1 [ Homo sapiens (human) ]

    Gene ID: 6422, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma.

    SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma.
    Dong L, Li Y, Song X, Sun C, Song X., Free PMC Article

    09/25/2024
    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling.

    MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling.
    Hu X, Liu Y, Shen H, Zhang T, Liang T., Free PMC Article

    09/17/2024
    Proteins linking APOE varepsilon4 with Alzheimer's disease.

    Proteins linking APOE ɛ4 with Alzheimer's disease.
    Oveisgharan S, Yu L, de Paiva Lopes K, Tasaki S, Wang Y, Menon V, Schneider JA, Seyfried NT, Bennett DA., Free PMC Article

    08/4/2024
    Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE.

    Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE.
    Ding Z, Wu L, Sun Y, Zhu Y, Zuo Q, Yuan L, Wang C, Sun L, Xu Y, Zhang Y., Free PMC Article

    06/3/2024
    LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.

    LncRNA DLG5-AS1 facilitates breast cancer cell proliferation and invasion by promoting EZH2-mediated transcriptional silencing of SFRP1.
    Cai Y, Liu Y, Sun Y, Ren Y.

    05/31/2024
    Study of the effect of sFRP1 protein on molecules involved in the regulation of DNA methylation in CML cell line.

    Study of the effect of sFRP1 protein on molecules involved in the regulation of DNA methylation in CML cell line.
    Demirkiran N, Aydin B, Pehlivan M, Yuce Z, Sercan HO.

    04/22/2024
    SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue.

    SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue.
    Gregory KJ, Mason H, Casaubon J, Schneider SS., Free PMC Article

    04/4/2024
    Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis.

    Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis.
    Yi J, Wu M, Zheng Z, Zhou Q, Li X, Lu Y, Liu P., Free PMC Article

    11/13/2023
    Hsa_circ_0001445 works as a cancer suppressor via miR-576-5p/SFRP1 axis regulation in ovarian cancer.

    Hsa_circ_0001445 works as a cancer suppressor via miR-576-5p/SFRP1 axis regulation in ovarian cancer.
    Wu Y, Zhou J, Li Y, Shi X, Shen F, Chen M, Chen Y, Wang J., Free PMC Article

    10/20/2023
    H3K27me3 Inactivates SFRP1 to Promote Cell Proliferation via Wnt/beta-Catenin Signaling Pathway in Esophageal Squamous Cell Carcinoma.

    H3K27me3 Inactivates SFRP1 to Promote Cell Proliferation via Wnt/β-Catenin Signaling Pathway in Esophageal Squamous Cell Carcinoma.
    Zhou M, Yu S, Liu Y, Shu S, Xu Y, Liu M, Ge Y, Fan H.

    05/18/2023
    [Clinical Significance of SFRP1 Gene Methylation in Patients with Childhood Acute Lymphoblastic Leukemia].

    [Clinical Significance of SFRP1 Gene Methylation in Patients with Childhood Acute Lymphoblastic Leukemia].
    Yan J, Wang WP, Li X, Han W, Qi FQ, Gao JZ.

    05/15/2023
    The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.

    The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
    Wang Q, Qi Y, Xiong F, Wang D, Wang B, Chen Y., Free PMC Article

    11/19/2022
    UVB-induced SFRP1 methylation potentiates skin damage by promoting cell apoptosis and DNA damage.

    UVB-induced SFRP1 methylation potentiates skin damage by promoting cell apoptosis and DNA damage.
    Liang J, Liu L, Tang H, Ma Q, Sang Y, Kang X.

    09/17/2022
    Expression of Tumor Suppressor SFRP1 Predicts Biological Behaviors and Prognosis: A Potential Target for Oral Squamous Cell Carcinoma.

    Expression of Tumor Suppressor SFRP1 Predicts Biological Behaviors and Prognosis: A Potential Target for Oral Squamous Cell Carcinoma.
    Chen C, Zhang Y, Liu Y, Hang L, Yang J., Free PMC Article

    08/6/2022
    Mechanical stress reduces secreted frizzled-related protein expression and promotes temporomandibular joint osteoarthritis via Wnt/beta-catenin signaling.

    Mechanical stress reduces secreted frizzled-related protein expression and promotes temporomandibular joint osteoarthritis via Wnt/β-catenin signaling.
    Cai S, Zou Y, Zhao Y, Lin H, Zheng D, Xu L, Lu Y.

    06/18/2022
    sFRP1 Expression Regulates Wnt Signaling in Chronic Myeloid Leukemia K562 Cells.

    sFRP1 Expression Regulates Wnt Signaling in Chronic Myeloid Leukemia K562 Cells.
    Pehlivan M, Caliskan C, Yuce Z, Sercan HO.

    05/21/2022
    Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors.

    Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors.
    Donega V, van der Geest AT, Sluijs JA, van Dijk RE, Wang CC, Basak O, Pasterkamp RJ, Hol EM., Free PMC Article

    04/23/2022
    LINC00092 Suppresses the Malignant Progression of Breast Invasive Ductal Carcinoma Through Modulating SFRP1 Expression by Sponging miR-1827.

    LINC00092 Suppresses the Malignant Progression of Breast Invasive Ductal Carcinoma Through Modulating SFRP1 Expression by Sponging miR-1827.
    Zhao CM, Li LL, Xu JW, Li ZW, Shi P, Jiang R., Free PMC Article

    04/9/2022
    Silencing of MBD2 and EZH2 inhibits the proliferation of colorectal carcinoma cells by rescuing the expression of SFRP.

    Silencing of MBD2 and EZH2 inhibits the proliferation of colorectal carcinoma cells by rescuing the expression of SFRP.
    Xie Y, Wang F, Yu J, Zhang J, Liu Y, Li M, Qi J., Free PMC Article

    01/22/2022
    Secreted Frizzled-Related Protein 1 Promotes Odontoblastic Differentiation and Reparative Dentin Formation in Dental Pulp Cells.

    Secreted Frizzled-Related Protein 1 Promotes Odontoblastic Differentiation and Reparative Dentin Formation in Dental Pulp Cells.
    Ipposhi K, Tomokiyo A, Ono T, Yamashita K, Alhasan MA, Hasegawa D, Hamano S, Yoshida S, Sugii H, Itoyama T, Ogawa M, Maeda H., Free PMC Article

    11/22/2021
    Concurrent Evaluation of the Expression and Methylation of secreted frizzled-related protein 2 along with beta-catenin Expression in Patients with non-M3 Acute Myeloid Leukemia.

    Concurrent Evaluation of the Expression and Methylation of secreted frizzled-related protein 2 along with beta-catenin Expression in Patients with non-M3 Acute Myeloid Leukemia.
    Mirzaeyan F, Chahardouli B, Mirzaeian A, Alizad Ghandforoush N, Alimoghaddam K, Rostami S., Free PMC Article

    10/23/2021
    Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia.

    Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia.
    Zhou LB, Cao Q, Ding Q, Sun WL, Li ZY, Zhao M, Lin XW, Zhou GP, Fan WX.

    10/2/2021
    Loss of SFRP1 expression is a key progression event in gastrointestinal stromal tumor pathogenesis.

    Loss of SFRP1 expression is a key progression event in gastrointestinal stromal tumor pathogenesis.
    Liang CW, Yang CY, Flavin R, Fletcher JA, Lu TP, Lai IR, Li YI, Chang YL, Lee JC.

    07/24/2021
    High-risk HPV infection modulates the promoter hypermethylation of APC, SFRP1, and PTEN in cervical cancer patients of North India.

    High-risk HPV infection modulates the promoter hypermethylation of APC, SFRP1, and PTEN in cervical cancer patients of North India.
    Kadian LK, Yadav R, Nanda S, Gulshan G, Sharma S, Yadav C.

    07/17/2021
    Wnt antagonist secreted frizzled-related protein I (sFRP1) may be involved in the osteogenic differentiation of periodontal ligament cells in chronic apical periodontitis.

    Wnt antagonist secreted frizzled-related protein I (sFRP1) may be involved in the osteogenic differentiation of periodontal ligament cells in chronic apical periodontitis.
    Yang F, Huang D, Xu L, Xu W, Yi X, Zhou X, Ye L, Zhang L.

    05/1/2021
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