| Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis. | Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis.
Qi B, Wang HY, Ma X, Chi YF, Gui C., Free PMC Article | 10/22/2024 |
| Role of secreted frizzled-related protein 4 in prediabetes and type 2 diabetes: a cross sectional study. | Role of secreted frizzled-related protein 4 in prediabetes and type 2 diabetes: a cross sectional study.
Sánchez-Pozos K, Granados-Silvestre MA, Nieto-Velázquez NG, Mejía-Blanquel MA, Galicia-Martínez N, Mandujano-Cerón J, Jaimes-Santoyo J, Ortiz-López MG., Free PMC Article | 06/12/2024 |
| Dupuytren's contracture-associated SNPs increase SFRP4 expression in non-immune cells including fibroblasts to enhance inflammation development. | Dupuytren's contracture-associated SNPs increase SFRP4 expression in non-immune cells including fibroblasts to enhance inflammation development.
Kida H, Jiang JJ, Matsui Y, Takahashi I, Hasebe R, Kawamura D, Endo T, Shibayama H, Kondo M, Nishio Y, Nishida K, Matsuno Y, Oikawa T, Kubota SI, Hojyo S, Iwasaki N, Hashimoto S, Tanaka Y, Murakami M. | 07/10/2023 |
| PBX1-promoted SFRP4 transcription inhibits cell proliferation and epithelial-mesenchymal transition in endometrial carcinoma. | PBX1-promoted SFRP4 transcription inhibits cell proliferation and epithelial-mesenchymal transition in endometrial carcinoma.
Guo L, Chen H, Chen J, Gao C, Fu X, Zhou S, Wu W, Li T, Lin J, Yang T, Chen Z, Cao L. | 06/23/2023 |
| Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging. | Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging.
Takaya K, Asou T, Kishi K., Free PMC Article | 11/12/2022 |
| Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture. | Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture.
Samulėnas G, Smalinskienė A, Rimdeika R, Braziulis K, Fomkinas M, Paškevičius R., Free PMC Article | 02/12/2022 |
| Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway. | Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway.
Li H, Zhao J, Sun J, Tian C, Jiang Q, Ding C, Gan Q, Shu P, Wang X, Qin J, Sun Y. | 02/12/2022 |
| Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells. | Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells.
Esfandyari S, Winston NJ, Fierro MA, Scoccia H, Stocco C., Free PMC Article | 01/22/2022 |
| The miR-181a-SFRP4 Axis Regulates Wnt Activation to Drive Stemness and Platinum Resistance in Ovarian Cancer. | The miR-181a-SFRP4 Axis Regulates Wnt Activation to Drive Stemness and Platinum Resistance in Ovarian Cancer.
Belur Nagaraj A, Knarr M, Sekhar S, Connor RS, Joseph P, Kovalenko O, Fleming A, Surti A, Nurmemmedov E, Beltrame L, Marchini S, Kahn M, DiFeo A., Free PMC Article | 09/18/2021 |
| Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions. | Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions.
Bernreuther C, Daghigh F, Möller K, Hube-Magg C, Lennartz M, Lutz F, Rico SD, Fraune C, Dum D, Luebke AM, Eichenauer T, Möller-Koop C, Schlomm T, Wittmer C, Huland H, Heinzer H, Graefen M, Haese A, Burandt E, Tsourlakis MC, Clauditz TS, Höflmayer D, Izbicki JR, Simon R, Sauter G, Minner S, Steurer S, Meiners J., Free PMC Article | 07/17/2021 |
| Hyperphosphatemia with low FGF7 and normal FGF23 and sFRP4 levels in the circulation characterizes pediatric hypophosphatasia. | Hyperphosphatemia with low FGF7 and normal FGF23 and sFRP4 levels in the circulation characterizes pediatric hypophosphatasia.
Whyte MP, Zhang F, Wenkert D, Mumm S, Berndt TJ, Kumar R., Free PMC Article | 05/22/2021 |
| Tumor suppressor role of sFRP4 in hepatocellular carcinoma via the Wnt/betacatenin signaling pathway. | Tumor suppressor role of sFRP‑4 in hepatocellular carcinoma via the Wnt/β‑catenin signaling pathway.
Wu Q, Xu C, Zeng X, Zhang Z, Yang B, Rao Z., Free PMC Article | 05/15/2021 |
| DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cells. | DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cells.
Mashhadikhan M, Kheiri H, Dehghanifard A. | 02/2/2021 |
| MicroRNA-96-5p Facilitates the Viability, Migration, and Invasion and Suppresses the Apoptosis of Cervical Cancer Cells byNegatively Modulating SFRP4. | MicroRNA-96-5p Facilitates the Viability, Migration, and Invasion and Suppresses the Apoptosis of Cervical Cancer Cells byNegatively Modulating SFRP4.
Zhang H, Chen R, Shao J., Free PMC Article | 01/9/2021 |
| Elevated circulating levels of secreted frizzled-related protein 4 in relation to insulin resistance and androgens in women with polycystic ovary syndrome. | Elevated circulating levels of secreted frizzled-related protein 4 in relation to insulin resistance and androgens in women with polycystic ovary syndrome.
Bicer M, Alarslan P, Guler A, Demir I, Aslanipour B, Calan M. | 11/21/2020 |
| miR-103a and miR-103b had high complementarity and conservation, modulated reporter gene expression through seed sequences in the 3'UTRs of CAV-1 and SFRP4 mRNA, and negatively regulated their mRNA and protein levels | Circulating miR-103 family as potential biomarkers for type 2 diabetes through targeting CAV-1 and SFRP4.
Luo M, Xu C, Luo Y, Wang G, Wu J, Wan Q. | 07/18/2020 |
| The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver. | The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
Hörbelt T, Knebel B, Fahlbusch P, Barbosa D, de Wiza DH, Van de Velde F, Van Nieuwenhove Y, Lapauw B, Thoresen GH, Al-Hasani H, Müller-Wieland D, Ouwens DM, Kotzka J. | 05/16/2020 |
| miR-943-3p accelerated the progression of airway inflammation and remodeling in allergic asthma via suppressing the activity of SFRP4 through Wnt signaling pathway in asthma patients and OVA-induced mice. | Interference of miR-943-3p with secreted frizzled-related proteins4 (SFRP4) in an asthma mouse model.
Shen J, Zhao J, Ye QY, Gu XD. | 01/11/2020 |
| high SFRP4 gene expression is associated with high Grade Group and recurrent prostate cancer after surgery | SFRP4 gene expression is increased in aggressive prostate cancer.
Sandsmark E, Andersen MK, Bofin AM, Bertilsson H, Drabløs F, Bathen TF, Rye MB, Tessem MB., Free PMC Article | 07/20/2019 |
| a significant correlation between pituitary adenoma invasion and low expression of WIF1 and sFRP4 is reported. | Aberrant expression of the sFRP and WIF1 genes in invasive non-functioning pituitary adenomas.
Song W, Qian L, Jing G, Jie F, Xiaosong S, Chunhui L, Yangfang L, Guilin L, Gao H, Yazhuo Z. | 05/11/2019 |
| A novel homozygous truncating mutation of the SFRP4 gene (NM_003014.3: c.315_316delCG; p.Asp106Argfs*26) in Pyle's disease was described. | A novel homozygous truncating mutation of the SFRP4 gene in Pyle's disease.
Chatron N, Lesca G, Labalme A, Rollat-Farnier PA, Monin P, Pichot E, Edery P, Sanlaville D, Rossi M. | 04/20/2019 |
| Both DKK2 and sFRP4 polymorphisms are found to play a crucial role; especially for smokers towards modulating risk for lung cancer. | High-order gene interactions between the genetic polymorphisms in Wnt and AhR pathway in modulating lung cancer susceptibility.
Bahl C, Singh N, Behera D, Sharma S. | 01/12/2019 |
| Results show that SFRP2 and SFRP4 typically associate with a poor prognosis of cancer patients concomitant with the expression of genes associated with epithelial-to-mesenchymal transition. SFRP2 and 4 are likely derived from the tumor stroma, and thus tend to increase in tumors as compared to normal tissues. | A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function.
Vincent KM, Postovit LM., Free PMC Article | 11/3/2018 |
| Data suggest that factors derived from conditioned medium of adipose-derived mesenchymal stem cells and sFRP4 significantly decrease cell viability and cell migration of breast tumor cells; this is accompanied by enhanced apoptosis via inhibition of canonical Wnt signal transduction. | The inhibitory influence of adipose tissue-derived mesenchymal stem cell environment and Wnt antagonism on breast tumour cell lines.
Visweswaran M, Arfuso F, Dilley RJ, Newsholme P, Dharmarajan A. | 11/3/2018 |
| increased SFRP4 and ficolin-3 levels are significantly associated with gestational diabetes mellitus development and might be important risk factors for this pregnancy complication. | Increased secreted frizzled-related protein 4 and ficolin-3 levels in gestational diabetes mellitus women.
Yuan XS, Zhang M, Wang HY, Jiang J, Yu B. | 10/6/2018 |