| RAB17 promotes endometrial cancer progression by inhibiting TFRC-dependent ferroptosis. | RAB17 promotes endometrial cancer progression by inhibiting TFRC-dependent ferroptosis.
Zhou X, Nie M, Xin X, Hua T, Zhang J, Shi R, Dong K, Shu W, Yan B, Wang H., Free PMC Article | 09/16/2024 |
| Downregulation of Rab17 promotes cell proliferation and invasion in non-small cell lung cancer through STAT3/HIF-1alpha/VEGF signaling. | Downregulation of Rab17 promotes cell proliferation and invasion in non-small cell lung cancer through STAT3/HIF-1α/VEGF signaling.
Wang M, Wang W, Ding J, Wang J, Zhang J., Free PMC Article | 03/6/2021 |
| ALS2, the small GTPase Rab17-interacting protein, regulates maturation and sorting of Rab17-associated endosomes. | ALS2, the small GTPase Rab17-interacting protein, regulates maturation and sorting of Rab17-associated endosomes.
Ono S, Otomo A, Murakoshi S, Mitsui S, Sato K, Fukuda M, Hadano S. | 09/26/2020 |
| Rab17 is rapidly recruited to efferosomes, followed by migration of the efferosome to the cell center where it intermixes with lysosomes and undergoes Rab17-dependent vesiculation. | Rab17 mediates intermixing of phagocytosed apoptotic cells with recycling endosomes.
Yin C, Argintaru D, Heit B., Free PMC Article | 04/11/2020 |
| Mass spectrometry and immunofluorescence microscopy of efferosomes and phagosomes in macrophages demonstrated that efferosomes lacked the proteins required for antigen presentation and instead recruited the recycling regulator Rab17. | Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis.
Yin C, Kim Y, Argintaru D, Heit B., Free PMC Article | 09/2/2017 |
| Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk MAPK signaling. | Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk pathway.
Qi J, Zhao P, Li F, Guo Y, Cui H, Liu A, Mao H, Zhao Y, Zhang X., Free PMC Article | 04/23/2016 |
| Rab17 might act as a tumour suppressor gene in hepatocellular carcinoma , and the anti-tumour effects of Rab17 might be partially mediated by the Erk pathway. | Rab17 inhibits the tumourigenic properties of hepatocellular carcinomas via the Erk pathway.
Wang K, Mao Z, Liu L, Zhang R, Liang Q, Xiong Y, Yuan W, Wei L. | 11/21/2015 |
| These results suggest that Rab17 and Rab17-mediated REs are involved in Streptococcus pyogenes-containing autophagosome-like vacuole formation. | Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion.
Haobam B, Nozawa T, Minowa-Nozawa A, Tanaka M, Oda S, Watanabe T, Aikawa C, Maruyama F, Nakagawa I. | 07/25/2015 |
| Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. | ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.
von Thun A, Birtwistle M, Kalna G, Grindlay J, Strachan D, Kolch W, von Kriegsheim A, Norman JC. | 02/16/2013 |
| Data reveal new functions for recycling endosomes and Rab17 in pigmentation through a distal step in the process of melanosome release via filopodia. | The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking.
Beaumont KA, Hamilton NA, Moores MT, Brown DL, Ohbayashi N, Cairncross O, Cook AL, Smith AG, Misaki R, Fukuda M, Taguchi T, Sturm RA, Stow JL. | 07/16/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |