| Dynamics and necessity of SIRT1 for maternal-zygotic transition. | Dynamics and necessity of SIRT1 for maternal-zygotic transition.
Nevoral J, Drutovic D, Vaskovicova M, Benc M, Liska F, Valentova I, Stachovicova S, Kubovciak J, Havrankova J, Shavit M, Monsef L, Iniesta-Cuerda M, Zalmanova T, Hosek P, Strejcek F, Kralickova M, Petr J., Free PMC Article | 09/25/2024 |
| m[6]A-Induced lncRNA MEG3 Promotes Cerebral Ischemia-Reperfusion Injury Via Modulating Oxidative Stress and Mitochondrial Dysfunction by hnRNPA1/Sirt2 Axis. | m(6)A-Induced lncRNA MEG3 Promotes Cerebral Ischemia-Reperfusion Injury Via Modulating Oxidative Stress and Mitochondrial Dysfunction by hnRNPA1/Sirt2 Axis.
Yao L, Peng P, Ding T, Yi J, Liang J. | 08/26/2024 |
| The SIRT2-AMPK axis regulates autophagy induced by acute liver failure. | The SIRT2-AMPK axis regulates autophagy induced by acute liver failure.
Zhang Q, Guo J, Shi C, Zhang D, Wang Y, Wang L, Gong Z., Free PMC Article | 08/13/2024 |
| The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination. | The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination.
Guo J, Nie J, Li D, Zhang H, Zhao T, Zhang S, Ma L, Lu J, Ji H, Li S, Tao S, Xu B., Free PMC Article | 08/12/2024 |
| Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. | Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis.
Hou D, Yu T, Lu X, Hong JY, Yang M, Zi Y, Ho TT, Lin H., Free PMC Article | 05/23/2024 |
| Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a. | Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a.
Yang C, Kang F, Huang X, Wu W, Hou G, Zheng K, Han M, Kan B, Zhang Z, Li J. | 04/16/2024 |
| Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice. | Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B. | 03/29/2024 |
| Oligodendrocyte-derived exosomes-containing SIRT2 ameliorates depressive-like behaviors and restores hippocampal neurogenesis and synaptic plasticity via the AKT/GSK-3beta pathway in depressed mice. | Oligodendrocyte-derived exosomes-containing SIRT2 ameliorates depressive-like behaviors and restores hippocampal neurogenesis and synaptic plasticity via the AKT/GSK-3β pathway in depressed mice.
Zhang H, Xie XH, Xu SX, Wang C, Sun S, Song X, Li R, Li N, Feng Y, Duan H, Li D, Liu Z., Free PMC Article | 03/6/2024 |
| Sirtuin 2 up-regulation suppresses the anti-tumour activity of exhausted natural killer cells in mesenteric lymph nodes in murine colorectal carcinoma. | Sirtuin 2 up-regulation suppresses the anti-tumour activity of exhausted natural killer cells in mesenteric lymph nodes in murine colorectal carcinoma.
Jiang B, Ke C, Zhou H, Xia T, Xie X, Xu H. | 03/6/2024 |
| Sirtuin2 suppresses the polarization of regulatory T cells toward T helper 17 cells through repressing the expression of signal transducer and activator of transcription 3 in a mouse colitis model. | Sirtuin2 suppresses the polarization of regulatory T cells toward T helper 17 cells through repressing the expression of signal transducer and activator of transcription 3 in a mouse colitis model.
Ge L, Xu M, Huang M, Liu S, Zhou Z, Xia Z, Zhao Q, Zhou F., Free PMC Article | 02/29/2024 |
| Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. | Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.
Malgulwar PB, Danussi C, Dharmaiah S, Johnson W, Singh A, Rai K, Rao A, Huse JT., Free PMC Article | 01/9/2024 |
| Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis. | Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis.
Zhao Q, Xia N, Xu J, Wang Y, Feng L, Su D, Cheng Z., Free PMC Article | 01/4/2024 |
| SIRT2 transgenic over-expression does not impact lifespan in mice. | SIRT2 transgenic over-expression does not impact lifespan in mice.
Wu LE, Fiveash CE, Bentley NL, Kang MJ, Govindaraju H, Barbour JA, Wilkins BP, Hancock SE, Madawala R, Das A, Massudi H, Li C, Kim LJ, Wong ASA, Marinova MB, Sultani G, Das A, Youngson NA, Le Couteur DG, Sinclair DA, Turner N., Free PMC Article | 12/27/2023 |
| SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1. | SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1.
Li Y, Bie J, Song C, Li Y, Zhang T, Li H, Zhao L, You F, Luo J., Free PMC Article | 12/18/2023 |
| Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation. | Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation.
Dai B, Liu S, Shen W, Chen L, Zhou Q, Han L, Zhang Q, Shan L., Free PMC Article | 12/5/2023 |
| Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells. | Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells.
Chen Y, Zhou C, Abdelhamid M, Jung CG, Michikawa M. | 11/13/2023 |
| SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease. | SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease.
Sola-Sevilla N, Mesa-Lombardo A, Aleixo M, Expósito S, Diaz-Perdigón T, Azqueta A, Zamani F, Suzuki T, Maioli S, Eroli F, Matton A, Ramírez MJ, Solas M, Tordera RM, Martín ED, Puerta E., Free PMC Article | 11/6/2023 |
| SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury. | SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury.
Yang X, Chang HC, Tatekoshi Y, Mahmoodzadeh A, Balibegloo M, Najafi Z, Wu R, Chen C, Sato T, Shapiro J, Ardehali H., Free PMC Article | 10/10/2023 |
| Role of SIRT2 in intestinal barrier under cold exposure. | Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B. | 09/6/2023 |
| A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma. | A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma.
Schmidt AV, Monga SP, Prochownik EV, Goetzman ES., Free PMC Article | 08/30/2023 |
| SIRT2 Deficiency Aggravates Diet-Induced Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites. | SIRT2 Deficiency Aggravates Diet-Induced Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites.
Li X, Du Y, Xue C, Kang X, Sun C, Peng H, Fang L, Han Y, Xu X, Zhao C., Free PMC Article | 08/23/2023 |
| Deacetylation via SIRT2 prevents keratin-mutation-associated injury and keratin aggregation. | Deacetylation via SIRT2 prevents keratin-mutation-associated injury and keratin aggregation.
Sun J, Li P, Gui H, Rittié L, Lombard DB, Rietscher K, Magin TM, Xie Q, Liu L, Omary MB., Free PMC Article | 07/27/2023 |
| Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model. | Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT. | 06/21/2023 |
| SIRT2 regulates extracellular vesicle-mediated liver-bone communication. | SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q., Free PMC Article | 06/3/2023 |
| Deacetylation of Septin4 by SIRT2 (Silent Mating Type Information Regulation 2 Homolog-2) Mitigates Damaging of Hypertensive Nephropathy. | Deacetylation of Septin4 by SIRT2 (Silent Mating Type Information Regulation 2 Homolog-2) Mitigates Damaging of Hypertensive Nephropathy.
Zhang Y, Zhang N, Zou Y, Song C, Cao K, Wu B, You S, Lu S, Wang D, Xu J, Huang X, Zhang P, Fan Z, Liu J, Cheng Z, Zhang Z, Kong C, Cao L, Sun Y., Free PMC Article | 03/10/2023 |