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    Slc2a5 solute carrier family 2 member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65197, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    crystal structures of GLUT5 from Rattus norvegicus and Bos taurus in open outward- and open inward-facing conformations, respectively

    Structure and mechanism of the mammalian fructose transporter GLUT5.
    Nomura N, Verdon G, Kang HJ, Shimamura T, Nomura Y, Sonoda Y, Hussien SA, Qureshi AA, Coincon M, Sato Y, Abe H, Nakada-Nakura Y, Hino T, Arakawa T, Kusano-Arai O, Iwanari H, Murata T, Kobayashi T, Hamakubo T, Kasahara M, Iwata S, Drew D., Free PMC Article

    04/30/2016
    Hexose transporter-mediated glucose uptake was greater in duodenum and jejunum compared with ileum.

    Coordinated, diurnal hexose transporter expression in rat small bowel: implications for small bowel resection.
    Houghton SG, Iqbal CW, Duenes JA, Fatima J, Kasparek MS, Sarr MG., Free PMC Article

    12/6/2011
    Vagal innervation appears to differentially mediate the diurnal changes in hexose transporter mRNA and protein expression in the rat jejunum by posttranscriptional, and/or posttranslational processes.

    The diurnal periodicity of hexose transporter mRNA and protein levels in the rat jejunum: role of vagal innervation.
    Houghton SG, Zarroug AE, Duenes JA, Fernandez-Zapico ME, Sarr MG.

    07/29/2011
    investigation of influence of dietary carbohydrates on expression of Glut5 in small intestine: Glut5 mRNA increased with fructose perfusion and age, a pattern that matched that of Pol II binding and histone H3 acetylation at Glut5 promoter

    Diet-induced epigenetic regulation in vivo of the intestinal fructose transporter Glut5 during development of rat small intestine.
    Suzuki T, Douard V, Mochizuki K, Goda T, Ferraris RP.

    05/21/2011
    regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents

    Positive regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents.
    Sakar Y, Nazaret C, Lettéron P, Ait Omar A, Avenati M, Viollet B, Ducroc R, Bado A., Free PMC Article

    05/3/2010
    The expression and metabolism of GLUT5 during the postnatal developmental process are reported.

    Developmental reprogramming of rat GLUT5 requires glucocorticoid receptor translocation to the nucleus.
    Douard V, Choi HI, Elshenawy S, Lagunoff D, Ferraris RP., Free PMC Article

    01/21/2010
    The essential role of chloride and fructose absorbing Slc2a5 is reported.

    Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5.
    Singh AK, Amlal H, Haas PJ, Dringenberg U, Fussell S, Barone SL, Engelhardt R, Zuo J, Seidler U, Soleimani M., Free PMC Article

    01/21/2010
    Dexamethasone sensitizes the neonatal intestine to fructose induction of intestinal fructose transporter (Slc2A5) function.

    Dexamethasone sensitizes the neonatal intestine to fructose induction of intestinal fructose transporter (Slc2A5) function.
    Douard V, Cui XL, Soteropoulos P, Ferraris RP., Free PMC Article

    01/21/2010
    insulin is capable of increasing the abundance and functional activity of GLUT5 in skeletal muscle cells, most likely mediated via activation of the GLUT5 promoter

    Insulin regulates the expression of the GLUT5 transporter in L6 skeletal muscle cells.
    Hajduch E, Litherland GJ, Turban S, Brot-Laroche E, Hundal HS.

    01/21/2010
    Short-term fructose feeding increases the expression of glucose transporter 5 in both young and aging adult rats. Increased brain expression of glucose transporter 5 is important in the role of fructose as an alternative energy source.

    Expression of fructose sensitive glucose transporter in the brains of fructose-fed rats.
    Shu HJ, Isenberg K, Cormier RJ, Benz A, Zorumski CF.

    01/21/2010
    T3 and fructose coordinately enhance expression of Slc2a5 gene in the small intestine during weaning period.

    Triiodothyronine (T3) and fructose coordinately enhance expression of the GLUT5 gene in the small intestine of rats during weaning period.
    Mochizuki K, Sakaguchi N, Goda T.

    01/21/2010
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