| SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation. | SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation.
Hu X, Liu R, Hou J, Peng W, Wan S, Xu M, Li Y, Zhang G, Zhai X, Liang P, Cui H. | 09/24/2022 |
| Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex. | Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex.
Dong C, Zhang R, Xu L, Liu B, Chu X. | 03/19/2022 |
| BAF57 Is a Potential Determinant of Colorectal Cancer Malignancy. | BAF57 Is a Potential Determinant of Colorectal Cancer Malignancy.
Suzumura H, Tsuruta M, Okabayashi K, Shigeta K, Seishima R, Ishida T, Shimada T, Asada Y, Koishikawa K, Akimoto S, Itano O, Hasegawa H, Kitagawa Y. | 11/22/2021 |
| Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1. | Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.
Sievers P, Sill M, Blume C, Tauziede-Espariat A, Schrimpf D, Stichel D, Reuss DE, Dogan H, Hartmann C, Mawrin C, Hasselblatt M, Stummer W, Schick U, Hench J, Frank S, Ketter R, Schweizer L, Schittenhelm J, Puget S, Brandner S, Jaunmuktane Z, Küsters B, Abdullaev Z, Pekmezci M, Snuderl M, Ratliff M, Herold-Mende C, Unterberg A, Aldape K, Ellison DW, Wesseling P, Reifenberger G, Wick W, Perry A, Varlet P, Pfister SM, Jones DTW, von Deimling A, Sahm F, German Consortium “Aggressive Meningiomas”., Free PMC Article | 10/30/2021 |
| Long noncoding RNA HOTTIP promotes the metastatic potential of ovarian cancer through the regulation of the miR-615-3p/SMARCE1 pathway. | Long noncoding RNA HOTTIP promotes the metastatic potential of ovarian cancer through the regulation of the miR-615-3p/SMARCE1 pathway.
Wu H, Wei HY, Chen QQ. | 10/9/2021 |
| BAF57/SMARCE1 Interacting with Splicing Factor SRSF1 Regulates Mechanical Stress-Induced Alternative Splicing of Cyclin D1. | BAF57/SMARCE1 Interacting with Splicing Factor SRSF1 Regulates Mechanical Stress-Induced Alternative Splicing of Cyclin D1.
Feng J, Xu X, Fan X, Yi Q, Tang L., Free PMC Article | 07/24/2021 |
| The importance of genetic counseling and screening for people with pathogenic SMARCE1 variants: A family study. | The importance of genetic counseling and screening for people with pathogenic SMARCE1 variants: A family study.
Shoakazemi A, Hewitt A, Smith MJ, du Plessis D, Thomas O, Stivaros SM, Deniz K, Hammerbeck-Ward C, Rutherford SA, King AT, Evans DG. | 07/10/2021 |
| Crystal structure of the HMG domain of human BAF57 and its interaction with four-way junction DNA. | Crystal structure of the HMG domain of human BAF57 and its interaction with four-way junction DNA.
Heo Y, Park JH, Kim J, Han J, Yun JH, Lee W. | 04/3/2021 |
| MicroRNA-802 induces hepatitis B virus replication and replication through regulating SMARCE1 expression in hepatocellular carcinoma. | MicroRNA-802 induces hepatitis B virus replication and replication through regulating SMARCE1 expression in hepatocellular carcinoma.
Wang Y, Cao J, Zhang S, Sun L, Nan Y, Yao H, Fan J, Zhu LY, Yu L., Free PMC Article | 08/22/2020 |
| A de novo splicing mutation in SMARCE1 was identified in a patient with Angelman-like syndrome. | Identification of a de novo splicing variant in the Coffin-Siris gene, SMARCE1, in a patient with Angelman-like syndrome.
Aguilera C, Gabau E, Laurie S, Baena N, Derdak S, Capdevila N, Ramirez A, Delgadillo V, García-Catalan MJ, Brun C, Guitart M, Ruiz A., Free PMC Article | 03/16/2019 |
| Study showed, for the first time, that SMARCE1 immunostaining is a highly sensitive biomarker for clear cell meningioma, useful as a routine diagnostic biomarker. | Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.
Tauziede-Espariat A, Parfait B, Besnard A, Lacombe J, Pallud J, Tazi S, Puget S, Lot G, Terris B, Cohen J, Vidaud M, Figarella-Branger D, Monnien F, Polivka M, Adle-Biassette H, Varlet P., Free PMC Article | 01/26/2019 |
| High SMARCE1 expression is associated with eventual relapse and metastasis in breast cancer. | SMARCE1 is required for the invasive progression of in situ cancers.
Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB., Free PMC Article | 06/2/2018 |
| miR-29a promotes hepatitis B virus (HBV) replication and expression through regulating SMARCE1 in HBV-infected HepG2.2.15 cells. | miR-29a promotes hepatitis B virus replication and expression by targeting SMARCE1 in hepatoma carcinoma.
Wu HJ, Zhuo Y, Zhou YC, Wang XW, Wang YP, Si CY, Wang XH., Free PMC Article | 04/28/2018 |
| the malignancy risk in schwannomatosis is not well defined but may include an increased risk of malignant peripheral nerve sheath tumor in SMARCB1 Imaging protocols are also proposed for SMARCB1 and LZTR1 schwannomatosis and SMARCE1-related meningioma predisposition. | Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 2 and Related Disorders.
Evans DGR, Salvador H, Chang VY, Erez A, Voss SD, Druker H, Scott HS, Tabori U. | 03/24/2018 |
| BAF57, BAF60a and SNF5 might act as novel pro-senescence factors in both normal and tumor human skin cells | Cellular senescence regulated by SWI/SNF complex subunits through p53/p21 and p16/pRB pathway.
He L, Chen Y, Feng J, Sun W, Li S, Ou M, Tang L. | 11/18/2017 |
| We report here three additional individuals with clinical features consistent with CSS and alterations in SMARCE1, one of which is novel. The probands all exhibited dysmorphic facial features, moderate developmental and cognitive delay, poor growth, and hypoplastic digital nails/phalanges, including digits not typically affected in the other genes associated with CSS. | SMARCE1, a rare cause of Coffin-Siris Syndrome: Clinical description of three additional cases.
Zarate YA, Bhoj E, Kaylor J, Li D, Tsurusaki Y, Miyake N, Matsumoto N, Phadke S, Escobar L, Irani A, Hakonarson H, Schrier Vergano SA., Free PMC Article | 10/28/2017 |
| SMARCE1 mutational hits, including novel SMARCE1 mutations, were found in six of eight tested patients with clear cell meningioma | SMARCE1 mutation screening in classification of clear cell meningiomas.
Smith MJ, Ahn S, Lee JI, Bulman M, Plessis DD, Suh YL. | 08/19/2017 |
| SMARCE1 plays an essential role in breast cancer metastasis by protecting cells against anoikis through the HIF1A/PTK2 pathway. | SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway.
Sethuraman A, Brown M, Seagroves TN, Wu ZH, Pfeffer LM, Fan M., Free PMC Article | 07/15/2017 |
| An exhaustive analysis of the BAF57 molecular and biochemical properties, cellular functions, loss-of-function phenotypes in living organisms and pathological manifestations in cases of human mutations. [review] | The developmental and pathogenic roles of BAF57, a special subunit of the BAF chromatin-remodeling complex.
Lomelí H, Castillo-Robles J. | 05/6/2017 |
| a family with a pediatric CCM patient and an adult CCM patient and several asymptomatic relatives carrying a germline SMARCE1 mutation. | A heritable form of SMARCE1-related meningiomas with important implications for follow-up and family screening.
Gerkes EH, Fock JM, den Dunnen WF, van Belzen MJ, van der Lans CA, Hoving EW, Fakkert IE, Smith MJ, Evans DG, Olderode-Berends MJ., Free PMC Article | 09/17/2016 |
| Addition of the EGFR inhibitor gefitinib restores the sensitivity of SMARCE1-knockdown cells to MET and ALK inhibitors in NSCLCs. Our findings link SMARCE1 to EGFR oncogenic signaling and suggest targeted treatment options for SMARCE1-deficient tumors. | SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer.
Papadakis AI, Sun C, Knijnenburg TA, Xue Y, Grernrum W, Hölzel M, Nijkamp W, Wessels LF, Beijersbergen RL, Bernards R, Huang S., Free PMC Article | 12/19/2015 |
| The results suggested that BAF57 is involved in ovarian cancer cell growth and sensitivity to anticancer agents, and that BAF57 may be a target for ovarian cancer therapy. | Expression of BAF57 in ovarian cancer cells and drug sensitivity.
Yamaguchi T, Kurita T, Nishio K, Tsukada J, Hachisuga T, Morimoto Y, Iwai Y, Izumi H., Free PMC Article | 08/8/2015 |
| BAF complex gene SMARCE1 is mutated in Coffin-Siris syndrome patients. | Numerous BAF complex genes are mutated in Coffin-Siris syndrome.
Miyake N, Tsurusaki Y, Matsumoto N. | 08/1/2015 |
| Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SmarCE1 gene. | Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SMARCB1, SMARCA4, SMARCE1, and ARID1A.
Kosho T, Okamoto N, Coffin-Siris Syndrome International Collaborators. | 08/1/2015 |
| Since both TTF1 and SMARCE1 are involved in chromatin remodeling, our results imply an epigenetic regulatory mechanism for T-cell recruitment that invites deciphering. | Overexpression of SMARCE1 is associated with CD8+ T-cell infiltration in early stage ovarian cancer.
Giannakakis A, Karapetsas A, Dangaj D, Lanitis E, Tanyi J, Coukos G, Sandaltzopoulos R. | 04/4/2015 |