| BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation. | BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation.
Wong DCP, Xiao J, Chew TW, Pan M, Lee CJM, Ang JW, Yow I, Thivakar T, Ackers-Johnson M, Lee NJW, Foo RS, Kanchanawong P, Low BC., Free PMC Article | 11/12/2022 |
| BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation. | BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation.
Pan M, Chew TW, Wong DCP, Xiao J, Ong HT, Chin JFL, Low BC., Free PMC Article | 04/16/2022 |
| BNIP-2 is a kinesin-1 adapter involved in vesicular transportation in the cytoplasm and that association with cargos depends on interaction of the CRAL-TRIO domain with membrane phosphatidylserine. | BNIP-2 binds phosphatidylserine, localizes to vesicles, and is transported by kinesin-1.
Akamatsu R, Ishida-Kitagawa N, Aoyama T, Oka C, Kawaichi M. | 09/26/2015 |
| BNIP-2 directly interacted with the motor and tail domains of KIF5B via its BCH domain. | KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation.
Yi P, Chew LL, Zhang Z, Ren H, Wang F, Cong X, Zheng L, Luo Y, Ouyang H, Low BC, Zhou YT., Free PMC Article | 08/22/2015 |
| Data imply that SIRT1 may mediate MPP(+)-induced cytotoxicity, possibly through the regulation of BNIP2. | SIRT1 deficiency attenuates MPP+-induced apoptosis in dopaminergic cells.
Park G, Jeong JW, Kim JE. | 03/19/2011 |
| Inhibition of BNIP-2 expression did not affect the susceptibility to NK cell-mediated killing. | Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.
Scott GB, Bowles PA, Wilson EB, Meade JL, Low BC, Davison A, Blair GE, Cook GP. | 10/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGermline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.
Kelly JL, Novak AJ, Fredericksen ZS, Liebow M, Ansell SM, Dogan A, Wang AH, Witzig TE, Call TG, Kay NE, Habermann TM, Slager SL, Cerhan JR. An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Shimada M, Miyagawa T, Kawashima M, Tanaka S, Honda Y, Honda M, Tokunaga K. | 09/15/2010 |
| Our results suggest that the caspase-mediated cleavage of BNIP-2 and BNIP-XL could result in the release of the BCH domain or smaller fragments that are crucial for their proapoptotic activities. | Cleavage of BNIP-2 and BNIP-XL by caspases.
Valencia CA, Cotten SW, Liu R. | 01/21/2010 |
| BNIP-2 in vivo induces cell dynamics by recruiting Cdc42 | BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain.
Zhou YT, Guy GR, Low BC. | 01/21/2010 |
| BNIP-2 has a role in regulating cell dynamics with a novel Rho GTPase-activating protein, BPGAP1 | Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1.
Shang X, Zhou YT, Low BC. | 01/21/2010 |
| Transfection of the bnip2 cDNA in neuroblastoma cell line results in massive cell death counteracted by Bcl-2 overexpression; bnip2 is the mediator of the anti-apoptotic activity of estrogens in a variety of cells | Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2.
Belcredito S, Vegeto E, Brusadelli A, Ghisletti S, Mussi P, Ciana P, Maggi A. | 01/21/2010 |
| BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. | BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.
Qin W, Hu J, Guo M, Xu J, Li J, Yao G, Zhou X, Jiang H, Zhang P, Shen L, Wan D, Gu J. | 01/21/2010 |