| Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis. | Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis.
Wang H, Shan X, Ren M, Shang M, Zhou C., Free PMC Article | 01/15/2022 |
| Clathrin switches transforming growth factor-beta role to pro-tumorigenic in liver cancer. | Clathrin switches transforming growth factor-β role to pro-tumorigenic in liver cancer.
Caballero-Díaz D, Bertran E, Peñuelas-Haro I, Moreno-Càceres J, Malfettone A, López-Luque J, Addante A, Herrera B, Sánchez A, Alay A, Solé X, Serrano T, Ramos E, Fabregat I. | 06/5/2021 |
| Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis. | Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.
Rondelet A, Lin YC, Singh D, Porfetye AT, Thakur HC, Hecker A, Brinkert P, Schmidt N, Bendre S, Müller F, Mazul L, Widlund PO, Bange T, Hiller M, Vetter IR, Bird AW., Free PMC Article | 09/19/2020 |
| These results suggest a novel paradigm in cell biology, wherein clathrin plaques act as platforms capable of recruiting branched cortical actin, which in turn anchors intermediate filaments, both essential for striated muscle formation and function. | Clathrin plaques and associated actin anchor intermediate filaments in skeletal muscle.
Franck A, Lainé J, Moulay G, Lemerle E, Trichet M, Gentil C, Benkhelifa-Ziyyat S, Lacène E, Bui MT, Brochier G, Guicheney P, Romero N, Bitoun M, Vassilopoulos S., Free PMC Article | 06/29/2019 |
| our results demonstrate that CKAP5 is important in oocyte maturation and early embryo development, and CKAP5 might work together with CLTC in mouse oocyte maturation | Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG., Free PMC Article | 09/23/2017 |
| SP-A transiently enhances the basal protein expression of CHC and alpha-adaptin. | Surfactant Protein A Enhances Constitutive Immune Functions of Clathrin Heavy Chain and Clathrin Adaptor Protein 2.
Moulakakis C, Steinhäuser C, Biedziak D, Freundt K, Reiling N, Stamme C. | 07/1/2017 |
| MiR-199a-5p suppresses tumorigenesis by targeting CLTC in hepatocellular carcinoma. | MiR-199a-5p suppresses tumorigenesis by targeting clathrin heavy chain in hepatocellular carcinoma.
Huang GH, Shan H, Li D, Zhou B, Pang PF. | 03/18/2017 |
| PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones. | The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain.
Park BC, Yim YI, Zhao X, Olszewski MB, Eisenberg E, Greene LE., Free PMC Article | 08/27/2016 |
| The clathrin-mediated endocytic machinery combines with Dab2 to facilitate the endocytosis of RGD-integrin-beta3 clusters. | Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.
Yu CH, Rafiq NB, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang YH, Kawauchi K, Jones GE, Sheetz MP., Free PMC Article | 05/21/2016 |
| Taken together, these results show that CLTC plays an important role in spindle assembly and chromosome congression through a microtubule correlation mechanism during mouse oocyte maturation. | Clathrin heavy chain 1 is required for spindle assembly and chromosome congression in mouse oocytes.
Zhao J, Wang L, Zhou HX, Liu L, Lu A, Li GP, Schatten H, Liang CG. | 04/5/2014 |
| Auditory inner hair cells use dynamin-dependent endocytosis via clathrin-mediated endocytosis. | Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, Wichmann C, Moser T., Free PMC Article | 03/15/2014 |
| Data indicate that dynamin, clathrin, adaptor protein complex-2 (AP2), and amphiphysin contribute to the depolarization-evoked entry in endocytosis. | Molecular components required for resting and stimulated endocytosis of botulinum neurotoxins by glutamatergic and peptidergic neurons.
Meng J, Wang J, Lawrence GW, Dolly JO. | 12/21/2013 |
| This study reveals a novel functional role of clathrin-coated structure in GMR signaling and the oncogenesis of JAK2V617F. | Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2.
Chen PH, Chien FC, Lee SP, Chan WE, Lin IH, Liu CS, Lee FJ, Lai JS, Chen P, Yang-Yen HF, Yen JJ., Free PMC Article | 03/2/2013 |
| The authors report that Dab2, previously described as an inhibitor of Wnt/beta-catenin signalling, selectively recruits LRP6 to the clathrin-dependent endocytic route, thereby sequestering it from caveolin-mediated endocytosis. | Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin.
Jiang Y, He X, Howe PH., Free PMC Article | 07/21/2012 |
| Microtubule associated protein 1B, a microtubule stabilizing protein, and clathrin heavy chain, the major component of the clathrin triskelion, were identified as interaction partners for dystonin-a | MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin.
Bhanot K, Young KG, Kothary R. | 03/10/2012 |
| A1AT associated with clathrin heavy chains, but not with caveolin-1 in the plasma membrane fraction of endothelial cells. | Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.
Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I., Free PMC Article | 01/21/2010 |
| neither clathrin nor AP-2 is essential for the internalization of epidermal growth factor | Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells.
Hinrichsen L, Harborth J, Andrees L, Weber K, Ungewickell EJ. | 01/21/2010 |