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    MIR411 microRNA 411 [ Homo sapiens (human) ]

    Gene ID: 693121, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A-to-I edited miR-411-5p targets MET and promotes TKI response in NSCLC-resistant cells.

    A-to-I edited miR-411-5p targets MET and promotes TKI response in NSCLC-resistant cells.
    Romano G, Le P, Nigita G, Saviana M, Micalo L, Lovat F, Del Valle Morales D, Li H, Nana-Sinkam P, Acunzo M., Free PMC Article

    05/12/2023
    Circulatory miR-411-5p as a Novel Prognostic Biomarker for Major Adverse Cardiovascular Events in Patients with Atrial Fibrillation.

    Circulatory miR-411-5p as a Novel Prognostic Biomarker for Major Adverse Cardiovascular Events in Patients with Atrial Fibrillation.
    Nopp S, van der Bent ML, Kraemmer D, Königsbrügge O, Wojta J, Pabinger I, Ay C, Nossent AY., Free PMC Article

    03/6/2023
    Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis.

    Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis.
    Zou M, Shen J, Wu Y, Zhong C, Fang L, Zhu F, Duan S.

    05/7/2022
    The alerting expression of microRNA-411 predicts clinical prognosis and regulates tumor progression of glioblastoma.

    The alerting expression of microRNA-411 predicts clinical prognosis and regulates tumor progression of glioblastoma.
    Fan W, Yu X, Li K, Zhu M., Free PMC Article

    02/19/2022
    Interference with lncRNA NEAT1 promotes the proliferation, migration, and invasion of trophoblasts by upregulating miR-411-5p and inhibiting PTEN expression.

    Interference with lncRNA NEAT1 promotes the proliferation, migration, and invasion of trophoblasts by upregulating miR-411-5p and inhibiting PTEN expression.
    Fan X, Lou J, Zheng X, Wang Y, Wang J, Luo M, Hu M.

    12/11/2021
    Long noncoding RNA PCED1BAS1 promotes pancreatic ductal adenocarcinoma progression by regulating the miR4113p/HIF1alpha axis.

    Long non‑coding RNA PCED1B‑AS1 promotes pancreatic ductal adenocarcinoma progression by regulating the miR‑411‑3p/HIF‑1α axis.
    Zhang Y, Ma H, Chen C., Free PMC Article

    12/4/2021
    Long non-coding RNA PSMA3-AS1 promotes glioma progression through modulating the miR-411-3p/HOXA10 pathway.

    Long non-coding RNA PSMA3-AS1 promotes glioma progression through modulating the miR-411-3p/HOXA10 pathway.
    Huang T, Chen Y, Zeng Y, Xu C, Huang J, Hu W, Chen X, Fu H., Free PMC Article

    10/23/2021
    Circ_0082182 promotes oncogenesis and metastasis of colorectal cancer in vitro and in vivo by sponging miR-411 and miR-1205 to activate the Wnt/beta-catenin pathway.

    Circ_0082182 promotes oncogenesis and metastasis of colorectal cancer in vitro and in vivo by sponging miR-411 and miR-1205 to activate the Wnt/β-catenin pathway.
    Liu R, Deng P, Zhang Y, Wang Y, Peng C., Free PMC Article

    07/10/2021
    Up-regulation of circ_0000353 impedes the proliferation and metastasis of non-small cell lung cancer cells via adsorbing miR-411-5p and increasing forkhead box O1.

    Up-regulation of circ_0000353 impedes the proliferation and metastasis of non-small cell lung cancer cells via adsorbing miR-411-5p and increasing forkhead box O1.
    Zhao WX, Tang YL, Wang WH, Bao MW.

    06/12/2021
    Up-regulation of SNHG15 facilitates cell proliferation, migration, invasion and suppresses cell apoptosis in breast cancer by regulating miR-411-5p/VASP axis.

    Up-regulation of SNHG15 facilitates cell proliferation, migration, invasion and suppresses cell apoptosis in breast cancer by regulating miR-411-5p/VASP axis.
    Liu LB, Jiang ZJ, Jiang XL, Wang S.

    03/20/2021
    Dysregulation of LncRNA ANRIL mediated by miR-411-3p inhibits the malignant proliferation and tumor stem cell like property of multiple myeloma via hypoxia-inducible factor 1alpha.

    Dysregulation of LncRNA ANRIL mediated by miR-411-3p inhibits the malignant proliferation and tumor stem cell like property of multiple myeloma via hypoxia-inducible factor 1α.
    Wang M, Zhao HY, Zhang JL, Wan DM, Li YM, Jiang ZX.

    03/13/2021
    Upregulated miR4115p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.

    Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.
    Zhang C, Wang H, Deng M, He L, Ping F, He Y, Fan Z, Cheng B, Xia J., Free PMC Article

    02/20/2021
    MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia.

    MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia.
    van der Kwast RVCT, Woudenberg T, Quax PHA, Nossent AY., Free PMC Article

    12/26/2020
    miRNA-411 Regulates Chondrocyte Autophagy in Osteoarthritis by Targeting Hypoxia-Inducible Factor 1 alpha (HIF-1alpha).

    miRNA-411 Regulates Chondrocyte Autophagy in Osteoarthritis by Targeting Hypoxia-Inducible Factor 1 alpha (HIF-1α).
    Yang F, Huang R, Ma H, Zhao X, Wang G., Free PMC Article

    12/12/2020
    MicroRNA-411 plays a protective role in diabetic retinopathy through targeted regulating Robo4.

    MicroRNA-411 plays a protective role in diabetic retinopathy through targeted regulating Robo4.
    Hu K, Li JL, Yuan XW.

    12/12/2020
    Prognostic and predictive roles of microRNA411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer.

    Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer.
    Wei W, Liu C., Free PMC Article

    10/31/2020
    MiR-411 inhibits gastric cancer proliferation and migration through targeting SETD6.

    MiR-411 inhibits gastric cancer proliferation and migration through targeting SETD6.
    Bai TL, Liu YB, Li BH.

    09/12/2020
    RT-PCR showed that the mRNA level of CDKN2B-AS1 was significantly upregulated while the miR-411-3p was downregulated in ovarian cancer cell lines.

    Long noncoding RNA CDKN2B-AS1 interacts with miR-411-3p to regulate ovarian cancer in vitro and in vivo through HIF-1a/VEGF/P38 pathway.
    Wang Y, Huang Y, Liu H, Su D, Luo F, Zhou F.

    06/27/2020
    Low miR411 Expression Promotes Renal Cell Carcinoma Progression.

    Down-Regulation of Circular RNA_000926 Attenuates Renal Cell Carcinoma Progression through miRNA-411-Dependent CDH2 Inhibition.
    Zhang D, Yang XJ, Luo QD, Fu DL, Li ZL, Zhang P, Chong T.

    04/4/2020
    Overexpression of MiR-411 results in the decrease of the proliferation of non-small cell lung cancer cells.

    MiR-411-5p acts as a tumor suppressor in non-small cell lung cancer through targeting PUM1.
    Xia LH, Yan QH, Sun QD, Gao YP.

    11/16/2019
    Study shows that miR-411-5p edited in position 5 was significantly dysregulated in tissues as well as in exosomes of Non-Small Cell Lung Cancer (NSCLC) patients, suggesting a potential targetome shift relevant to lung cancer biology.

    Tissue and exosomal miRNA editing in Non-Small Cell Lung Cancer.
    Nigita G, Distefano R, Veneziano D, Romano G, Rahman M, Wang K, Pass H, Croce CM, Acunzo M, Nana-Sinkam P., Free PMC Article

    10/19/2019
    SLC27A2 is required for the transcriptional induction of miR-411 in ovarian cancer. Reduced miR-411 expression contributes to ovarian cancer chemo-resistance.

    SLC27A2 regulates miR-411 to affect chemo-resistance in ovarian cancer.
    Chen FD, Chen HH, Ke SC, Zheng LR, Zheng XY.

    07/6/2019
    miR-411-5p/3p are required for Non small cell lung carcinoma development by suppressing SPRY4 and TXNIP; thus, the miR-411-SPRY4-AKT axis might act as a promising target for lung cancer therapy clinically.

    Oncogenic microRNA-411 promotes lung carcinogenesis by directly targeting suppressor genes SPRY4 and TXNIP.
    Zhang C, Wang H, Liu X, Hu Y, Ding L, Zhang X, Sun Q, Li Y., Free PMC Article

    05/11/2019
    Overexpression of circular RNA circ_001569 indicates poor prognosis in hepatocellular carcinoma and promotes cell growth and metastasis by sponging miR-411-5p and miR-432-5p.

    Overexpression of circular RNA circ_001569 indicates poor prognosis in hepatocellular carcinoma and promotes cell growth and metastasis by sponging miR-411-5p and miR-432-5p.
    Liu H, Xue L, Song C, Liu F, Jiang T, Yang X.

    01/5/2019
    To sum up, miR-411 is significantly down-regulated and plays a role as a tumor suppressor in renal cell carcinoma (RCC). Further studies are warranted to determine the mechanisms of miR-411 in RCC pathogenesis and define the target genes of miR-411 in RCC.

    MiR-411 functions as a tumor suppressor in renal cell cancer.
    Zhang X, Zhang M, Cheng J, Lv Z, Wang F, Cai Z.

    06/16/2018
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