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    MIR556 microRNA 556 [ Homo sapiens (human) ]

    Gene ID: 693141, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circular RNA circ_0096041 promotes osteosarcoma cell proliferation and migration via sponging miR-556-5p and regulating LIN28A expression.

    Circular RNA circ_0096041 promotes osteosarcoma cell proliferation and migration via sponging miR-556-5p and regulating LIN28A expression.
    Zhou F, Wu H, Yin Z, Zhou W, Chen W.

    03/14/2024
    circSLCO1B7 suppresses the malignant progression of hepatocellular carcinoma via the miR-556-3p/DAB2IP axis.

    circSLCO1B7 suppresses the malignant progression of hepatocellular carcinoma via the miR-556-3p/DAB2IP axis.
    Ju L, Zhou Q, Qi Q, She Y, Cai W, Cao Y, Lu R, Shao J, Chen L., Free PMC Article

    12/15/2023
    Down-regulation of long noncoding RNA HULC inhibits the inflammatory response in ankylosing spondylitis by reducing miR-556-5p-mediated YAP1 expression.

    Down-regulation of long noncoding RNA HULC inhibits the inflammatory response in ankylosing spondylitis by reducing miR-556-5p-mediated YAP1 expression.
    Yi L, Song C, Liu Y, Li D, Xiao T, Guo X, Wu Y., Free PMC Article

    08/3/2023
    Hsa_circ_0070661 inhibits cancer progression through miR-556-5p/TEK axis in lung adenocarcinoma.

    Hsa_circ_0070661 inhibits cancer progression through miR-556-5p/TEK axis in lung adenocarcinoma.
    Chen Y, Wu Y.

    05/17/2023
    N6-methyladenine- induced LINC00667 promoted breast cancer progression through m6A/KIAA1429 positive feedback loop.

    N6-methyladenine- induced LINC00667 promoted breast cancer progression through m6A/KIAA1429 positive feedback loop.
    Ren S, Zhang Y, Yang X, Li X, Zheng Y, Liu Y, Zhang X., Free PMC Article

    02/4/2023
    CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells.

    CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells.
    Hu F, Chen X, Gao J, Shen Y, Yang J.

    04/2/2022
    Circular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer.

    Circular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer.
    He J, Chu Z, Lai W, Lan Q, Zeng Y, Lu D, Jin S, Xu H, Su P, Yin D, Chu Z, Liu L., Free PMC Article

    02/12/2022
    Knock-down of microRNA miR-556-5p increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via activating NLR family pyrin domain containing 3 (NLRP3)-mediated pyroptotic cell death.

    Knock-down of microRNA miR-556-5p increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via activating NLR family pyrin domain containing 3 (NLRP3)-mediated pyroptotic cell death.
    Shi F, Zhang L, Liu X, Wang Y., Free PMC Article

    01/15/2022
    Targeting a novel hsa_circ_0000520/miR-556-5p/NLRP3 pathway-mediated cell pyroptosis and inflammation attenuates ovalbumin (OVA)-induced allergic rhinitis (AR) in mice models.

    Targeting a novel hsa_circ_0000520/miR-556-5p/NLRP3 pathway-mediated cell pyroptosis and inflammation attenuates ovalbumin (OVA)-induced allergic rhinitis (AR) in mice models.
    Yu X, Wang M, Zhao H, Cao Z.

    12/4/2021
    Down-regulation of miR-556-3p inhibits hemangioma cell proliferation and promotes apoptosis by targeting VEGFC.

    Down-regulation of miR-556-3p inhibits hemangioma cell proliferation and promotes apoptosis by targeting VEGFC.
    Jin W, Chen L, Gao F, Yang M, Liu Y, Wang B.

    06/5/2021
    SNHG1/miR-556-5p/TCF12 feedback loop enhances the tumorigenesis of meningioma through Wnt signaling pathway.

    SNHG1/miR-556-5p/TCF12 feedback loop enhances the tumorigenesis of meningioma through Wnt signaling pathway.
    Zhang Y, Yu R, Li Q, Li Y, Xuan T, Cao S, Zheng J.

    05/15/2021
    Knockdown of circ-ABCB10 promotes sensitivity of lung cancer cells to cisplatin via miR-556-3p/AK4 axis.

    Knockdown of circ-ABCB10 promotes sensitivity of lung cancer cells to cisplatin via miR-556-3p/AK4 axis.
    Wu Z, Gong Q, Yu Y, Zhu J, Li W., Free PMC Article

    11/21/2020
    MicroRNA-556-3p blocked the translation of DAB2IP at mRNA level by directly binding to 3'UTR of DAB2IP, enhancing the proliferation of esophageal tumor cells.

    MicroRNA-556-3p promotes the progression of esophageal cancer via targeting DAB2IP.
    Lu HB.

    12/21/2019
    this study indicated that a functional polymorphism of GSTM3 -rs1055259 reduced susceptibility of clear cell renal cell carcinoma in the Chinese population. It influenced GSTM3 protein synthesis by interfering miR-556 binding, subsequently suppressed ROS activity and clear cell renal cell carcinoma progression.

    A novel functional polymorphism of GSTM3 reduces clear cell renal cell carcinoma risk through enhancing its expression by interfering miR-556 binding.
    Wang Y, Yang ZY, Chen YH, Li F, Shen H, Yu Y, Huang HY, Shen ZY., Free PMC Article

    11/30/2019
    These findings suggest that DAB2IP is a direct target of miRNA-556-3p, and endogenous miRNA-556-3p expression shows inverse correlation with simultaneous DAB2IP expression in bladder cancer (BC)tissues and cells. miRNA-556-3p functions as a tumor promoter in tumorigenesis and metastasis of BC by targeting DAB2IP

    miRNA-556-3p promotes human bladder cancer proliferation, migration and invasion by negatively regulating DAB2IP expression.
    Feng C, Sun P, Hu J, Feng H, Li M, Liu G, Pan Y, Feng Y, Xu Y, Feng K, Feng Y.

    03/3/2018
    Results suggest that microRNAs miR-221-5p, miR-380-3p, miR-556-5p, miR-758-3p and miR-3074-3p are potential diagnostic biomarkers of lupus nephritis in patients with systemic lupus erythematosus (SLE).

    High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus.
    Navarro-Quiroz E, Pacheco-Lugo L, Lorenzi H, Díaz-Olmos Y, Almendrales L, Rico E, Navarro R, España-Puccini P, Iglesias A, Egea E, Aroca G., Free PMC Article

    07/15/2017
    miR-556-5p functions as an onco-miRNA and participates in prostate cancer carcinogenesis by suppressing PPP2R2A expression.

    Upregulation of miR-556-5p promoted prostate cancer cell proliferation by suppressing PPP2R2A expression.
    Zhao W, Cao L, Zeng S, Qin H, Men T.

    11/12/2016
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