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    MIR605 microRNA 605 [ Homo sapiens (human) ]

    Gene ID: 693190, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1.

    MicroRNA-605-3p Inhibited the Growth and Chemoresistance of Osteosarcoma Cells via Negatively Modulating RAF1.
    Wang M, Li W, Han G, Bai X, Xie J., Free PMC Article

    10/22/2024
    Long Noncoding RNA LINC01703 Exacerbates the Malignant Properties of Non-Small Cell Lung Cancer by Upregulating MACC1 in a MicroRNA-605-3p-Mediated Manner.

    Long Noncoding RNA LINC01703 Exacerbates the Malignant Properties of Non-Small Cell Lung Cancer by Upregulating MACC1 in a MicroRNA-605-3p-Mediated Manner.
    Wang Z, Zhang X, Zhang X, Jiang X, Li W., Free PMC Article

    02/5/2022
    Hsa-miR-605 regulates the proinflammatory chemokine CXCL5 in complex regional pain syndrome.

    Hsa-miR-605 regulates the proinflammatory chemokine CXCL5 in complex regional pain syndrome.
    Pande R, Parikh A, Shenoda B, Ramanathan S, Alexander GM, Schwartzman RJ, Ajit SK., Free PMC Article

    08/14/2021
    microRNA-605 rs2043556 polymorphisms affect clopidogrel therapy through modulation of CYP2B6 and P2RY12 in acute coronary syndrome patients.

    microRNA-605 rs2043556 polymorphisms affect clopidogrel therapy through modulation of CYP2B6 and P2RY12 in acute coronary syndrome patients.
    Zhou WL, Mo ZZ, Xiao FY, Dai W, Wang G, Zhou G, Zhang W, Chen BL.

    06/26/2021
    Significant Association of miR-605 rs2043556 with Susceptibility to Breast Cancer.

    Significant Association of miR-605 rs2043556 with Susceptibility to Breast Cancer.
    Kazemi A, Vallian S.

    05/15/2021
    CircDDX17 acts as a competing endogenous RNA for miR-605 in breast cancer progression.

    CircDDX17 acts as a competing endogenous RNA for miR-605 in breast cancer progression.
    Peng HH, Wen YG.

    05/8/2021
    SNHG16/miR-605-3p/TRAF6/NF-kappaB feedback loop regulates hepatocellular carcinoma metastasis.

    SNHG16/miR-605-3p/TRAF6/NF-κB feedback loop regulates hepatocellular carcinoma metastasis.
    Hu YL, Feng Y, Chen YY, Liu JZ, Su Y, Li P, Huang H, Mao QS, Xue WJ., Free PMC Article

    05/1/2021
    miR-605-5p promotes invasion and proliferation by targeting TNFAIP3 in non-small-cell lung cancer.

    miR-605-5p promotes invasion and proliferation by targeting TNFAIP3 in non-small-cell lung cancer.
    Liao Y, Cao L, Wang F, Pang R.

    03/20/2021
    MIR605 rs2043556 is associated with the occurrence of multiple primary tumors in TP53 p.(Arg337His) mutation carriers.

    MIR605 rs2043556 is associated with the occurrence of multiple primary tumors in TP53 p.(Arg337His) mutation carriers.
    Bandeira IC, Vieira IA, Andreis TF, Brussa Reis L, Macedo GS, Vianna FSL, Santos-Silva P, Palmero EI, Galvão HCR, Ramos CRN, Santiago KM, Achatz MI, da Costa AABA, Ashton-Prolla P.

    09/26/2020
    this study highlights the important roles of BLACAT1/miR-605-3p/VASP axis in glioma progression.

    LncRNA BLACAT1 regulates VASP expression via binding to miR-605-3p and promotes giloma development.
    Liu N, Hu G, Wang H, Wang Y, Guo Z.

    06/13/2020
    Circular RNA circ-VANGL1 is a competing endogenous RNA which contributes to bladder cancer progression by regulating miR-605-3p/VANGL1 pathway.

    Circular RNA circ-VANGL1 as a competing endogenous RNA contributes to bladder cancer progression by regulating miR-605-3p/VANGL1 pathway.
    Zeng Z, Zhou W, Duan L, Zhang J, Lu X, Jin L, Yu Y.

    03/21/2020
    Current meta-analysis indicate that the miR-605 rs2043556 may decrease susceptibility in Asian populations, especially allelic-G may be a protective factor for cancer in carriers [Meta-analysis].

    Association Between the Polymorphism in miR-605 and Cancer Susceptibility: a PRISMA-Compliant Meta-Analysis.
    Hu M, Yu Z, Luo D, Zhang H, Li J, Liang F, Chen R.

    09/14/2019
    the findings of this meta-analysis did not support an association between miR-605 rs2043556 polymorphism and cancer susceptibility.

    Lack of Association between miR-605 rs2043556 Polymorphism and Overall Cancer Risk: A Meta-analysis of Case-control Studies.
    Moazeni-Roodi A, Ghavami S, Hashemi M.

    04/27/2019
    Low miR605 expression is associated with melanoma.

    MicroRNA-605 functions as a tumor suppressor by targeting INPP4B in melanoma.
    Chen L, Cao Y, Rong D, Wang Y, Cao Y.

    07/28/2018
    EN2 is negatively regulated by miR-605, and down-regulation of miR-605 promotes the proliferation and invasion of prostate cancer (PCa) cells by up-regulating EN2, which leads to PCa development and progression

    Down-regulation of miR-605 promotes the proliferation and invasion of prostate cancer cells by up-regulating EN2.
    Zhou YJ, Yang HQ, Xia W, Cui L, Xu RF, Lu H, Xue Z, Zhang B, Tian ZN, Cao YJ, Xing ZY, Yin S, He XZ.

    11/4/2017
    MIR605 polymorphisms are associated with the risk of head and neck squamous cell carcinoma.

    Association of microRNA polymorphisms with the risk of head and neck squamous cell carcinoma in a Chinese population: a case-control study.
    Miao L, Wang L, Zhu L, Du J, Zhu X, Niu Y, Wang R, Hu Z, Chen N, Shen H, Ma H., Free PMC Article

    03/18/2017
    Data indicate that the microRNA miR-605 SNP (rs2043556) modifies the age of cancer onset in Li-Fraumeni syndrome (LFS) patients.

    A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndrome.
    Id Said B, Malkin D.

    05/9/2015
    Single-nucleotide polymorphism in MIRN605 is associated with biochemical recurrence in prostate cancer.

    Genetic variants in microRNAs and microRNA target sites predict biochemical recurrence after radical prostatectomy in localized prostate cancer.
    Huang SP, Lévesque E, Guillemette C, Yu CC, Huang CY, Lin VC, Chung IC, Chen LC, Laverdière I, Lacombe L, Fradet Y, Chang TY, Lee HZ, Juang SH, Bao BY.

    11/29/2014
    MiR-605 directly targets and represses PSMD10 expression.

    MiR-605 represses PSMD10/Gankyrin and inhibits intrahepatic cholangiocarcinoma cell progression.
    Li J, Tian F, Li D, Chen J, Jiang P, Zheng S, Li X, Wang S.

    11/22/2014
    miR-605 AG/GG genotype carriers had increased susceptibilities to colorectal cancer and gastric cancer in smokers

    Associations of lifestyle-related factors, hsa-miR-149 and hsa-miR-605 gene polymorphisms with gastrointestinal cancer risk.
    Zhang MW, Jin MJ, Yu YX, Zhang SC, Liu B, Jiang X, Pan YF, Li QI, Ma SY, Chen K.

    01/26/2013
    There was no significant association of SNPs of miR-149 and miR-605 with lung cancer.

    [Association of miR-605 and miR-149 genetic polymorphisms with related risk factors of lung cancer susceptibility].
    Zhang MW, Yu YX, Jin MJ, Pan YF, Jiang X, Li QL, Ma XY, Zhang SC, Chen K.

    10/1/2011
    MicroRNA miR-605 is transcriptionally activated by p53 interaction with its promotor region, and post-transcriptionally represses Mdm2.

    miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress.
    Xiao J, Lin H, Luo X, Luo X, Wang Z., Free PMC Article

    03/19/2011
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