| Analysis of the Expression of LSF Transcription Factor in the Regulation of Transcription and TSG101 during the Neoplastic Transformation of Endometrial Cells. | Analysis of the Expression of LSF Transcription Factor in the Regulation of Transcription and TSG101 during the Neoplastic Transformation of Endometrial Cells.
Ziemiński R, Stupak A, Kwiatek M, Gęca T, Warowicka A, Hejne K, Kwaśniewska A, Goździcka-Józefiak A, Kwaśniewski W., Free PMC Article | 04/23/2024 |
| Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions. | Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, Diwan GD, Carrero ZI, Ball CR, Hohl T, Kindler T, Rudolph-Hähnel P, Helm D, Schneider M, Nilsson A, Øra I, Imle R, Banito A, Russell RB, Jones BC, Lipka DB, Glimm H, Hübschmann D, Hartmann W, Fröhling S, Scholl C., Free PMC Article | 01/9/2024 |
| Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/beta-catenin signaling to alleviate preeclampsia. | Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/β-catenin signaling to alleviate preeclampsia.
Yang Z, Jia X, Deng Q, Luo M, Hou Y, Yue J, Mei J, Shan N, Wu Z. | 09/22/2023 |
| TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth. | TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth.
Basu A, Champagne RN, Patel NG, Nicholson ED, Weiss RJ., Free PMC Article | 06/28/2023 |
| Transcription factor cellular promoter 2 is required for upstream binding protein 1 -mediated angiogenesis. | Transcription factor cellular promoter 2 is required for upstream binding protein 1 -mediated angiogenesis.
Ren Y, YaneYang, Lu Q, Wang Q, Lu G, Wei Y, Zhou J. | 06/16/2023 |
| circITCH suppresses cell proliferation and metastasis through miR-660/TFCP2 pathway in melanoma. | circITCH suppresses cell proliferation and metastasis through miR-660/TFCP2 pathway in melanoma.
Zhang J, Cai Y, Sheng S, Zhao C, Jiang B., Free PMC Article | 06/18/2022 |
| DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter. | DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.
Shao K, Pu W, Zhang J, Guo S, Qian F, Glurich I, Jin Q, Ma Y, Ju S, Zhang Z, Ding W., Free PMC Article | 01/22/2022 |
| Transcription factors CP2 and YY1 as prognostic markers in head and neck squamous cell carcinoma: analysis of The Cancer Genome Atlas and a second independent cohort. | Transcription factors CP2 and YY1 as prognostic markers in head and neck squamous cell carcinoma: analysis of The Cancer Genome Atlas and a second independent cohort.
Schnoell J, Jank BJ, Kadletz-Wanke L, Stoiber S, Spielvogel CP, Gurnhofer E, Kenner L, Heiduschka G., Free PMC Article | 02/27/2021 |
| A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation. | A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation.
Le Loarer F, Cleven AHG, Bouvier C, Castex MP, Romagosa C, Moreau A, Salas S, Bonhomme B, Gomez-Brouchet A, Laurent C, Le Guellec S, Audard V, Giraud A, Ramos-Oliver I, Cleton-Jansen AM, Savci-Heijink DC, Kroon HM, Baud J, Pissaloux D, Pierron G, Sherwood A, Coindre JM, Bovée JVMG, Larousserie F, Tirode F. | 02/2/2021 |
| The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates alpha-tubulin. | The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin.
Chin HG, Esteve PO, Ruse C, Lee J, Schaus SE, Pradhan S, Hansen U., Free PMC Article | 01/2/2021 |
| A Feedback Loop Comprising EGF/TGFalpha Sustains TFCP2-Mediated Breast Cancer Progression. | A Feedback Loop Comprising EGF/TGFα Sustains TFCP2-Mediated Breast Cancer Progression.
Zhao Y, Kaushik N, Kang JH, Kaushik NK, Son SH, Uddin N, Kim MJ, Kim CG, Lee SJ. | 11/21/2020 |
| CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer. | CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.
Liu Y, Zhang X, Lin J, Chen Y, Qiao Y, Guo S, Yang Y, Zhu G, Pan Q, Wang J, Sun F., Free PMC Article | 09/12/2020 |
| MAGE-A11 and transcription factors SP1,TFCP2 and ZEB1 expression were associated with some clinical features in patients, such as pathological differentiation, tumor size, clinical stage, lymph node metastasis and distant metastasis. Patients with ESCC having high MAGE-A11 and transcription factors (SP1,TFCP2 and ZEB1) expression had a worse prognosis compared to the patients with low expression. | Expression and prognostic significance of MAGE-A11 and transcription factors (SP1,TFCP2 and ZEB1) in ESCC tissues.
Gu L, Sang M, Li J, Liu F, Wu Y, Liu S, Wang P, Shan B. | 01/18/2020 |
| Studies reveal that TFCP2, TFCP2L1, UBP1 belong to a transcription factors subfamily and involved in various aspects of cancer types and development as either proto-oncogenes or tumor suppressors. They can directly interact with each other; TFCP2, TFCP2L1 and UBP1 can form heteromeric DNA-binding complexes. In addition, TFCP2L1 can modulate the activity of TFCP2 and UBP1. [review] | TFCP2/TFCP2L1/UBP1 transcription factors in cancer.
Kotarba G, Krzywinska E, Grabowska AI, Taracha A, Wilanowski T. | 03/23/2019 |
| TFCP2 signaling is regulated by circular RNA hsa_circ_0023404 in the cervical cancer. | Circular RNA hsa_circ_0023404 exerts an oncogenic role in cervical cancer through regulating miR-136/TFCP2/YAP pathway.
Zhang J, Zhao X, Zhang J, Zheng X, Li F. | 11/10/2018 |
| Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A. Findings showed that a novel Late SV40 Factor and Aurora-A-signaling inhibition supports the rationale of using metformin as potential oral squamous cell carcinoma therapeutics. | Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A.
Chen CH, Tsai HT, Chuang HC, Shiu LY, Su LJ, Chiu TJ, Luo SD, Fang FM, Huang CC, Chien CY., Free PMC Article | 09/15/2018 |
| TFCP2 acts as a transcription co-factor that stimulates YAP transcription by facilitating YAP binding with YAP binding motif (YBF)-containing transcription factors. | TFCP2 Is Required for YAP-Dependent Transcription to Stimulate Liver Malignancy.
Zhang X, Sun F, Qiao Y, Zheng W, Liu Y, Chen Y, Wu Q, Liu X, Zhu G, Chen Y, Yu Y, Pan Q, Wang J. | 06/16/2018 |
| High expression of CP2c was significantly correlated with patient age, and higher histological grade, stage, and small and large vessel invasion in HCC tissues. | Diagnostic and prognostic relevance of CP2c and YY1 expression in hepatocellular carcinoma.
Kim JS, Son SH, Kim MY, Choi D, Jang IS, Paik SS, Chae JH, Uversky VN, Kim CG., Free PMC Article | 03/24/2018 |
| FQI1 mediates alteration of the tumor epigenome by DNMT1-LSF complex disruption, leading to aberrant DNA methylation and gene expression. | Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.
Chin HG, Ponnaluri VK, Zhang G, Estève PO, Schaus SE, Hansen U, Pradhan S., Free PMC Article | 02/10/2018 |
| The results suggest potential roles of LSF (TFCP2 ) as a growth regulator through control of the transcription of p21CIP1 in melanocytes and melanoma cells as well as a biomarker for nevus. | Transcription factor LSF (TFCP2) inhibits melanoma growth.
Goto Y, Yajima I, Kumasaka M, Ohgami N, Tanaka A, Tsuzuki T, Inoue Y, Fukushima S, Ihn H, Kyoya M, Ohashi H, Kawakami T, Bennett DC, Kato M., Free PMC Article | 12/17/2016 |
| Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1 pathway. | Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1.
Seol HS, Lee SE, Song JS, Rhee JK, Singh SR, Chang S, Jang SJ., Free PMC Article | 07/16/2016 |
| LSF is an important mediator in colorectal carcinoma tumorigenesis and progression, and LSF expression is an important index for and prognostic prediction. | LSF expression and its prognostic implication in colorectal cancer.
Jiang H, Du J, Jin J, Qi X, Pu Y, Fei B., Free PMC Article | 07/4/2015 |
| Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma | Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.
Grant TJ, Bishop JA, Christadore LM, Barot G, Chin HG, Woodson S, Kavouris J, Siddiq A, Gredler R, Shen XN, Sherman J, Meehan T, Fitzgerald K, Pradhan S, Briggs LA, Andrews WH, Sarkar D, Schaus SE, Hansen U., Free PMC Article | 05/12/2012 |
| Secreted OPN, induced by LSF, activates c-Met via a potential interaction between OPN and its cell surface receptor CD44. A significant correlation was observed among LSF, OPN, and activated c-Met levels in HCC. | c-Met activation through a novel pathway involving osteopontin mediates oncogenesis by the transcription factor LSF.
Yoo BK, Gredler R, Chen D, Santhekadur PK, Fisher PB, Sarkar D., Free PMC Article | 04/7/2012 |
| Inhibition of MMP-9 significantly abrogated LSF-induced angiogenesis as well as in vivo tumorigenesis, thus reinforcing the role of MMP-9 in facilitating LSF function. | Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9).
Santhekadur PK, Gredler R, Chen D, Siddiq A, Shen XN, Das SK, Emdad L, Fisher PB, Sarkar D., Free PMC Article | 03/24/2012 |