| Kruppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4alpha-mediated metabolic pathways. | Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.
Pan X, Hu S, Xu Y, Gopoju R, Zhu Y, Cassim Bawa FN, Wang H, Wang J, Batayneh Z, Clark A, Zeng Y, Lin L, Wang X, Yin L, Zhang Y., Free PMC Article | 05/30/2024 |
| CircITGA7 regulates malignant phenotypes in bladder cancer cells via targeting miR-330-3p/KLF10 axis. | CircITGA7 regulates malignant phenotypes in bladder cancer cells via targeting miR-330-3p/KLF10 axis.
Yang XX, Wang C. | 04/22/2024 |
| New Insights into the Role of KLF10 in Tissue Fibrosis. | New Insights into the Role of KLF10 in Tissue Fibrosis.
Yaseen U, Hwang S, Park S, Kim SB, Lee HJ, Cha JY., Free PMC Article | 02/2/2024 |
| A TGF-beta/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer. | A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer.
Dasgupta A, Gibbard DF, Schmitt RE, Arneson-Wissink PC, Ducharme AM, Bruinsma ES, Hawse JR, Jatoi A, Doles JD., Free PMC Article | 08/19/2023 |
| KLF10 knockdown negatively regulates CTRP3 to improve OGD/R-induced brain microvascular endothelial cell injury and barrier dysfunction through Nrf2/HO-1 signaling pathway. | KLF10 knockdown negatively regulates CTRP3 to improve OGD/R-induced brain microvascular endothelial cell injury and barrier dysfunction through Nrf2/HO-1 signaling pathway.
Zeng Y, Xu Y, Pan Y, Guo H. | 06/25/2023 |
| Kruppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors. | Krüppel-like factor 10 modulates stem cell phenotypes of pancreatic adenocarcinoma by transcriptionally regulating notch receptors.
Tsai YC, Cheng KH, Jiang SS, Hawse JR, Chuang SE, Chen SL, Huang TS, Ch'ang HJ., Free PMC Article | 06/15/2023 |
| Transcription factor AP-2 gamma/Kruppel-like factor 10 axis is involved in miR-3656-related dysfunction of endothelial cells in hypertension. | Transcription factor AP-2 gamma/Krüppel-like factor 10 axis is involved in miR-3656-related dysfunction of endothelial cells in hypertension.
Ren Y, Shi J, Liu S, Zhu W, Shao A, Qiao Y, Li Y, Liu Y, Cheng Y, Liu Y. | 03/13/2023 |
| KLF10 Functions as an Independent Prognosis Factor for Gastric Cancer. | KLF10 Functions as an Independent Prognosis Factor for Gastric Cancer.
Lin YM, Yeh KT, Yeh CM, Soon MS, Hsu LS., Free PMC Article | 07/2/2022 |
| KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7. | KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7.
Yang S, Jia L, Xiang J, Yang G, Qiu S, Kang L, Zheng P, Liang Z, Lu Y., Free PMC Article | 06/11/2022 |
| Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis. | Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis.
Wang S, Zha X, Ruan S, Yao S, Zhang X., Free PMC Article | 02/26/2022 |
| Positive feedback between lncRNA FLVCR1-AS1 and KLF10 may inhibit pancreatic cancer progression via the PTEN/AKT pathway. | Positive feedback between lncRNA FLVCR1-AS1 and KLF10 may inhibit pancreatic cancer progression via the PTEN/AKT pathway.
Lin J, Zhai S, Zou S, Xu Z, Zhang J, Jiang L, Deng X, Chen H, Peng C, Zhang J, Shen B., Free PMC Article | 02/19/2022 |
| KLF10 inhibits cell growth by regulating PTTG1 in multiple myeloma under the regulation of microRNA-106b-5p. | KLF10 inhibits cell growth by regulating PTTG1 in multiple myeloma under the regulation of microRNA-106b-5p.
Zhou M, Chen J, Zhang H, Liu H, Yao H, Wang X, Zhang W, Zhao Y, Yang N., Free PMC Article | 11/13/2021 |
| Hypoxic tumour cell-derived exosomal miR-340-5p promotes radioresistance of oesophageal squamous cell carcinoma via KLF10. | Hypoxic tumour cell-derived exosomal miR-340-5p promotes radioresistance of oesophageal squamous cell carcinoma via KLF10.
Chen F, Xu B, Li J, Yang X, Gu J, Yao X, Sun X., Free PMC Article | 09/4/2021 |
| High Expression of KLF10 Is Associated with Favorable Survival in Patients with Oral Squamous Cell Carcinoma. | High Expression of KLF10 Is Associated with Favorable Survival in Patients with Oral Squamous Cell Carcinoma.
Yeh CM, Lee YJ, Ko PY, Lin YM, Sung WW., Free PMC Article | 08/28/2021 |
| Our findings show that a KLF4 genomic variant (rs2236599) is associated with hydroxyurea treatment efficacy in sickle cell disease/beta-thalassemia compound heterozygous patients and two KLF10 genomic variants (rs980112, rs3191333) are associated with persistent HbF levels in nontransfusion dependent beta-thalassemia (NTDT) patients | Genomic variants in members of the Krüppel-like factor gene family are associated with disease severity and hydroxyurea treatment efficacy in β-hemoglobinopathies patients.
Stratopoulos A, Kolliopoulou A, Karamperis K, John A, Kydonopoulou K, Esftathiou G, Sgourou A, Kourakli A, Vlachaki E, Chalkia P, Theodoridou S, Papadakis MN, Gerou S, Symeonidis A, Katsila T, Ali BR, Papachatzopoulou A, Patrinos GP. | 05/9/2020 |
| targeting the KDM6A-KLF10 feedback loop may be beneficial to attenuate diabetes-induced kidney injury. | A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction.
Lin CL, Hsu YC, Huang YT, Shih YH, Wang CJ, Chiang WC, Chang PJ., Free PMC Article | 05/2/2020 |
| study illustrated a novel signaling cascade of LINC00641/miR-197-3p/KLF10/PTEN/PI3K/AKT pathway regulating bladder cancer development | LncRNA LINC00641 predicts prognosis and inhibits bladder cancer progression through miR-197-3p/KLF10/PTEN/PI3K/AKT cascade.
Li Z, Hong S, Liu Z. | 03/16/2019 |
| Klf10 silencing could inhibit bone differentiation of human periodontal ligament cells under mechanical force, which may be through regulation of hedgehog signaling pathway. | [Klf10 silencing inhibited mechanical force induced osteogenic differentiation of human periodontal ligament cells].
Yu XQ, Li YL, Gao JY, Liu H. | 02/23/2019 |
| Results from a study on gene expression variability markers in early-stage human embryos shows that KLF10 is a putative marker for the 3-day, 8-cell embryo stage. | Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.
Hasegawa Y, Taylor D, Ovchinnikov DA, Wolvetang EJ, de Torrenté L, Mar JC., Free PMC Article | 07/23/2018 |
| Zinc is capable of ameliorating the allogeneic immune reaction by enhancement of antigen-specific iTreg cells due to modulation of essential molecular targets by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1. | Zinc supplementation induces CD4(+)CD25(+)Foxp3(+) antigen-specific regulatory T cells and suppresses IFN-γ production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1.
Maywald M, Rink L. | 05/5/2018 |
| Thus, our study uncovers a novel regulatory mechanism underlying which KLF10 stability and its biological function are mediated by FBW7. | FBW7 targets KLF10 for ubiquitin-dependent degradation.
Yu S, Wang F, Tan X, Gao GL, Pan WJ, Luan Y, Ge X. | 02/17/2018 |
| In clinical specimens of lung adenocarcinoma, low KLF10 expression associated with decreased patient survival, consistent with a pivotal role for KLF10 in distinguishing the antiproliferative versus prometastatic functions of TGFbeta. Our results establish that KLF10 functions to suppress TGFb-induced EMT, establishing a molecular basis for the dichotomy of TGFb function during tumor progression. | Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism.
Mishra VK, Subramaniam M, Kari V, Pitel KS, Baumgart SJ, Naylor RM, Nagarajan S, Wegwitz F, Ellenrieder V, Hawse JR, Johnsen SA., Free PMC Article | 09/16/2017 |
| the findings show that TIEG1 is highly expressed in human keloids and that it directly binds and represses Smad7 promoter-mediated activation of TGF-beta/Smad2 signaling | TIEG1 Represses Smad7-Mediated Activation of TGF-β1/Smad Signaling in Keloid Pathogenesis.
Hu ZC, Shi F, Liu P, Zhang J, Guo D, Cao XL, Chen CF, Qu SQ, Zhu JY, Tang B. | 04/29/2017 |
| photoexposure decreases expression in fibroblasts and keratinocytes | Impact of exogenous stress on TGF-β inducible early gene 1 in human skin cells.
Sobilo L, Kurfürst R, Loubens V, Martin M, Mondon P, Jeanneton O, Heusèle C, Ossant F, Lespessailles E, Toumi H, Crabbe L, Schnebert S. | 10/29/2016 |
| TIEG-1 overexpression in normal human skin fibroblasts results in improved resistance to oxidative stress | TGF-beta-induced early gene-1 overexpression promotes oxidative stress protection and actin cytoskeleton rearrangement in human skin fibroblasts.
Leduc C, Sobilo L, Toumi H, Mondon P, Lespessailles E, Ossant F, Kurfurst R, Pichon C. | 08/6/2016 |