| Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice. | Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Sandovici I, Fernandez-Twinn DS, Campbell N, Cooper WN, Sekita Y, Zvetkova I, Ferland-McCollough D, Prosser HM, Oyama LM, Pantaleão LC, Cimadomo D, Barbosa de Queiroz K, Cheuk CSK, Smith NM, Kay RG, Antrobus R, Hoelle K, Ma MKL, Smith NH, Geyer SH, Reissig LF, Weninger WJ, Siddle K, Willis AE, Lam BYH, Bushell M, Ozanne SE, Constância M. | 10/2/2024 |
| Obesity-induced upregulation of miR-483-5p impairs the function and identity of pancreatic beta-cells. | Obesity-induced upregulation of miR-483-5p impairs the function and identity of pancreatic β-cells.
Yuan H, He M, Yang Q, Niu F, Zou Y, Liu C, Yang Yang, Liu A, Chang X, Chen F, Wu T, Han X, Zhang Y. | 09/25/2024 |
| miR-483-5p offsets functional and behavioural effects of stress in male mice through synapse-targeted repression of Pgap2 in the basolateral amygdala. | miR-483-5p offsets functional and behavioural effects of stress in male mice through synapse-targeted repression of Pgap2 in the basolateral amygdala.
Mucha M, Skrzypiec AE, Kolenchery JB, Brambilla V, Patel S, Labrador-Ramos A, Kudla L, Murrall K, Skene N, Dymicka-Piekarska V, Klejman A, Przewlocki R, Mosienko V, Pawlak R., Free PMC Article | 05/24/2023 |
| microRNA-483 Protects Pancreatic beta-Cells by Targeting ALDH1A3. | microRNA-483 Protects Pancreatic β-Cells by Targeting ALDH1A3.
Wang Z, Mohan R, Chen X, Matson K, Waugh J, Mao Y, Zhang S, Li W, Tang X, Satin LS, Tang X., Free PMC Article | 10/23/2021 |
| HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis. | HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis.
Liu D, Liu F, Li Z, Pan S, Xie J, Zhao Z, Liu Z, Zhang J, Liu Z., Free PMC Article | 09/18/2021 |
| the present study suggested that miR4833p promoted osteogenic differentiation of BMSCs by targeting STAT1, and miR4833 prepresent a potential therapeutic target for agerelated bone loss. | miR‑483‑3p regulates osteogenic differentiation of bone marrow mesenchymal stem cells by targeting STAT1.
Xiao Y, Guo Q, Jiang TJ, Yuan Y, Yang L, Wang GW, Xiao WF., Free PMC Article | 04/4/2020 |
| mTORC1 controls the histone deacetylase 4-dependent expression of miR-483-5p to stimulate chondrocyte hypertrophy | Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression.
Wang H, Zhang H, Sun Q, Yang J, Zeng C, Ding C, Cai D, Liu A, Bai X. | 01/11/2020 |
| The overexpression of miR4833p promoted apoptosis, increased caspase3 and 9 activity levels, and induced the protein expression of Bax/Bcl2 in the acute myocardial infarction model. | miR-483-3p regulates acute myocardial infarction by transcriptionally repressing insulin growth factor 1 expression.
Sun H, Cai J, Xu L, Liu J, Chen M, Zheng M, Wang L, Yang X. | 08/18/2018 |
| Transfection of hADSCs with inhibitors of miR-483-5p led to a significant increase of ERK1/2 phosphorylation in the nucleus. | miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
Chen K, He H, Xie Y, Zhao L, Zhao S, Wan X, Yang W, Mo Z., Free PMC Article | 07/30/2016 |
| miR-483 has opposite effects in alpha- and beta-pancreatic cells by targeting SOCS3. | Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells.
Mohan R, Mao Y, Zhang S, Zhang YW, Xu CR, Gradwohl G, Tang X., Free PMC Article | 11/7/2015 |
| the AT1R-regulated miR-483-3p as a potential negative regulator of steady-state levels of renin-angiotensin system components. | Angiotensin II-regulated microRNA 483-3p directly targets multiple components of the renin-angiotensin system.
Kemp JR, Unal H, Desnoyer R, Yue H, Bhatnagar A, Karnik SS., Free PMC Article | 05/23/2015 |
| Loss of miR-483 expression is associated with liver fibrosis. | Overexpression of miR-483-5p/3p cooperate to inhibit mouse liver fibrosis by suppressing the TGF-β stimulated HSCs in transgenic mice.
Li F, Ma N, Zhao R, Wu G, Zhang Y, Qiao Y, Han D, Xu Y, Xiang Y, Yan B, Jin J, Lv G, Wang L, Xu C, Gao X, Luo S., Free PMC Article | 04/18/2015 |
| miR-483 and miR-483* may play critical roles in early and later pathogenesis of OA, respectively, without the involvement of their host gene Igf2. | The expression of intronic miRNAs, miR-483 and miR-483*, and their host gene, Igf2, in murine osteoarthritis cartilage.
Qi Y, Ma N, Yan F, Yu Z, Wu G, Qiao Y, Han D, Xiang Y, Li F, Wang W, Gao X. | 05/10/2014 |
| miR-483-3p suppresses growth of squamous cell carcinomas due to its pro-apoptotic properties. | Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties.
Bertero T, Bourget-Ponzio I, Puissant A, Loubat A, Mari B, Meneguzzi G, Auberger P, Barbry P, Ponzio G, Rezzonico R., Free PMC Article | 03/8/2014 |
| Igf2-derived intronic miR-483, through downregulation of its target Socs3, regulates hepatoma cell proliferation | Igf2-derived intronic miR-483 promotes mouse hepatocellular carcinoma cell proliferation.
Ma N, Li F, Li D, Hui Y, Wang X, Qiao Y, Zhang Y, Xiang Y, Zhou J, Zhou L, Zheng X, Gao X. | 04/28/2012 |
| This study showed the up-regulation of miR-483-3p in 2 distinct models of wound healing: scratch-injured cultures of human keratinocytes and wounded skin in mice. | miR-483-3p controls proliferation in wounded epithelial cells.
Bertero T, Gastaldi C, Bourget-Ponzio I, Imbert V, Loubat A, Selva E, Busca R, Mari B, Hofman P, Barbry P, Meneguzzi G, Ponzio G, Rezzonico R. | 11/12/2011 |
| data suggest that miR-483-5p can be coexpressed together with its host gene, Igf2, and revealed the link between this miRNA and the IGF2 growth factor | Coexpression of an intronic microRNA and its host gene reveals a potential role for miR-483-5p as an IGF2 partner.
Ma N, Wang X, Qiao Y, Li F, Hui Y, Zou C, Jin J, Lv G, Peng Y, Wang L, Huang H, Zhou L, Zheng X, Gao X. | 08/20/2011 |
| miR-483-3p has a role in cancer at the IGF2/483 locus | Oncogenic role of miR-483-3p at the IGF2/483 locus.
Veronese A, Lupini L, Consiglio J, Visone R, Ferracin M, Fornari F, Zanesi N, Alder H, D'Elia G, Gramantieri L, Bolondi L, Lanza G, Querzoli P, Angioni A, Croce CM, Negrini M., Free PMC Article | 05/3/2010 |