| SNHG14 Elevates NFAT5 Expression Through Sequestering miR-375-3p to Promote MPP + -Induced Neuronal Apoptosis, Inflammation, and Oxidative Stress in Parkinson's Disease. | SNHG14 Elevates NFAT5 Expression Through Sequestering miR-375-3p to Promote MPP + -Induced Neuronal Apoptosis, Inflammation, and Oxidative Stress in Parkinson's Disease.
Xu F, Bian N, Li X. | 04/16/2024 |
| Circular RNA hsa_circ_0051246 acts as a microRNA-375 sponge to promote the progression of gastric cancer stem cells via YAP1. | Circular RNA hsa_circ_0051246 acts as a microRNA-375 sponge to promote the progression of gastric cancer stem cells via YAP1.
Deng M, Xu Y, Yao Y, Wang Y, Yan Q, Cheng M, Liu Y., Free PMC Article | 03/22/2024 |
| Ang II Controls the Expression of Mapkap1 by miR-375 and Affects the Function of Islet beta Cells. | Ang II Controls the Expression of Mapkap1 by miR-375 and Affects the Function of Islet β Cells.
Lin X, Cheng L, Wan Y, Yan Y, Zhang Z, Li X, Wu J, Wang X, Xu M., Free PMC Article | 07/31/2023 |
| Silencing METTL3 Stabilizes Atherosclerotic Plaques by Regulating the Phenotypic Transformation of Vascular Smooth Muscle Cells via the miR-375-3p/PDK1 Axis. | Silencing METTL3 Stabilizes Atherosclerotic Plaques by Regulating the Phenotypic Transformation of Vascular Smooth Muscle Cells via the miR-375-3p/PDK1 Axis.
Chen J, Lai K, Yong X, Yin H, Chen Z, Wang H, Chen K, Zheng J. | 05/10/2023 |
| MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia. | MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia.
McCoy MG, Jamaiyar A, Sausen G, Cheng HS, Pérez-Cremades D, Zhuang R, Chen J, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW. | 02/14/2023 |
| MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathway. | MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathway.
Gong R, Han R, Zhuang X, Tang W, Xu G, Zhang L, Wu J, Ma J., Free PMC Article | 09/24/2022 |
| MiR-375 potentially enhances GnRH expression by targeting Sp1 in GT1-7 cells. | MiR-375 potentially enhances GnRH expression by targeting Sp1 in GT1-7 cells.
Li H, Li X, Zhang D, Li J, Cui S. | 12/4/2021 |
| Long non-coding RNA SNHG5 regulates ulcerative colitis via microRNA-375 / Janus kinase-2 axis. | Long non-coding RNA SNHG5 regulates ulcerative colitis via microRNA-375 / Janus kinase-2 axis.
Li H, Xuan J, Zhang W, An Z, Fan X, Lu M, Tian Y., Free PMC Article | 11/13/2021 |
| MiR-375 silencing attenuates pro-inflammatory macrophage response and foam cell formation by targeting KLF4. | MiR-375 silencing attenuates pro-inflammatory macrophage response and foam cell formation by targeting KLF4.
Qiu Y, Xu J, Yang L, Zhao G, Ding J, Chen Q, Zhang N, Yang R, Wang J, Li S, Zhang L. | 09/4/2021 |
| miR-375 acts as a novel factor modulating pituitary prolactin synthesis through Rasd1 and Esr1. | miR-375 acts as a novel factor modulating pituitary prolactin synthesis through Rasd1 and Esr1.
Zhang J, Gao J, Zhang D, Liu H, Gou K, Cui S. | 08/7/2021 |
| miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene. | miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene.
Kumar A, Ren Y, Sundaram K, Mu J, Sriwastva MK, Dryden GW, Lei C, Zhang L, Yan J, Zhang X, Park JW, Merchant ML, Teng Y, Zhang HG., Free PMC Article | 07/31/2021 |
| Long Noncoding RNA LNC_000898 Alleviates Cardiomyocyte Apoptosis and Promotes Cardiac Repair After Myocardial Infarction Through Modulating the miR-375/PDK1 Axis. | Long Noncoding RNA LNC_000898 Alleviates Cardiomyocyte Apoptosis and Promotes Cardiac Repair After Myocardial Infarction Through Modulating the miR-375/PDK1 Axis.
Yan M, Liu Q, Jiang Y, Wang B, Ji Y, Liu H, Xie Y. | 01/16/2021 |
| Mimic expression of miR-375 significantly prevented H/R-induced cardiomyocyte injury by decreasing caspase-3 activity through upregulation of the NLK gene | Overexpression of miR-375 Protects Cardiomyocyte Injury following Hypoxic-Reoxygenation Injury.
Ali Sheikh MS., Free PMC Article | 06/6/2020 |
| This study provides evidence that miR-375 could regulate Kupffer cells to improve immune function in mice with liver failure. | Silencing of microRNA-375 affects immune function in mice with liver failure by upregulating astrocyte elevated gene-1 through reducing apoptosis of Kupffer cells.
Ke QH, Chen HY, He ZL, Lv Z, Xu XF, Qian YG, Zheng SS. | 01/4/2020 |
| MiR-7, miR-9 and miR-375 contribute to effect of Exendin-4 on pancreatic beta-cells in high-fat-diet-fed mice. | MiR-7, miR-9 and miR-375 contribute to effect of Exendin-4 on pancreatic β-cells in high-fat-diet-fed mice.
Guo C, Sun YQ, Li Q, Zhang JC. | 04/6/2019 |
| Overexpression of miR-375 prevents nasal mucosa cells from apoptosis and ameliorates allergic rhinitis via inhibition of the JAK2/STAT3 pathway. | miR-375 prevents nasal mucosa cells from apoptosis and ameliorates allergic rhinitis via inhibiting JAK2/STAT3 pathway.
Wang T, Chen D, Wang P, Xu Z, Li Y. | 10/13/2018 |
| Repression of miR-375 led to the activation of 3-phosphoinositide-dependent protein kinase 1 (PDK-1) and increased AKT phosphorylation on Thr-308 in experimental hearts | Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis.
Garikipati VNS, Verma SK, Jolardarashi D, Cheng Z, Ibetti J, Cimini M, Tang Y, Khan M, Yue Y, Benedict C, Nickoloff E, Truongcao MM, Gao E, Krishnamurthy P, Goukassian DA, Koch WJ, Kishore R., Free PMC Article | 06/9/2018 |
| miR-375 has multiple functions with importance in the formation of pancreatic beta-cell identity, control of beta cell mass and regulation of insulin secretion. (Review) | The small RNA miR-375 - a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function.
Eliasson L. | 05/19/2018 |
| Circulating microRNA-375 is biomarker of pancreatic beta cell death in experimental diabetes mellitus. | Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds.
Song I, Roels S, Martens GA, Bouwens L., Free PMC Article | 11/4/2017 |
| we revealed miR-375-3p negatively regulated osteogenesis by targeting LRP5 and beta-catenin | miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin.
Sun T, Li CT, Xiong L, Ning Z, Leung F, Peng S, Lu WW., Free PMC Article | 08/26/2017 |
| studies suggest that miR-375 is negatively associated with BMPAC function and survival and IL-10-mediated repression of miR-375 enhances BMPAC survival and function. | Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction.
Garikipati VN, Krishnamurthy P, Verma SK, Khan M, Abramova T, Mackie AR, Qin G, Benedict C, Nickoloff E, Johnson J, Gao E, Losordo DW, Houser SR, Koch WJ, Kishore R., Free PMC Article | 10/29/2016 |
| miR375 overexpression inhibited proliferation but promoted apoptosis in P19 cells, and the associated mRNAs and proteins were decreased during differentiation. | MicroRNA-375 overexpression influences P19 cell proliferation, apoptosis and differentiation through the Notch signaling pathway.
Wang L, Song G, Liu M, Chen B, Chen Y, Shen Y, Zhu J, Zhou X., Free PMC Article | 10/22/2016 |
| miR-375 gene dosage in pancreatic beta-cells: implications for regulation of beta-cell mass and biomarker development | miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development.
Latreille M, Herrmanns K, Renwick N, Tuschl T, Malecki MT, McCarthy MI, Owen KR, Rülicke T, Stoffel M., Free PMC Article | 07/30/2016 |
| Data show that microRNA miR-375 appears to negatively regulate the development of enteroendocrine cells, and emerges as a potential target to modulate the function of the enteroendocrine system. | The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage.
Knudsen LA, Petersen N, Schwartz TW, Egerod KL. | 04/16/2016 |
| It was concluded that voltage-gated Na(+) channels are regulated by miR-375 in insulin-secreting cells, and validate that the exocytotic machinery is controlled by miR-375 also in INS-1 832/13 cells. | Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells.
Salunkhe VA, Esguerra JL, Ofori JK, Mollet IG, Braun M, Stoffel M, Wendt A, Eliasson L., Free PMC Article | 12/5/2015 |