| Increased miR-200c levels disrupt palatal fusion by affecting apoptosis, cell proliferation, and cell migration. | Increased miR-200c levels disrupt palatal fusion by affecting apoptosis, cell proliferation, and cell migration.
Won HJ, Won HS, Shin JO. | 06/12/2023 |
| MicroRNA-200c-5p Regulates Migration and Differentiation of Myoblasts via Targeting Adamts5 in Skeletal Muscle Regeneration and Myogenesis. | MicroRNA-200c-5p Regulates Migration and Differentiation of Myoblasts via Targeting Adamts5 in Skeletal Muscle Regeneration and Myogenesis.
Liu Y, Yao Y, Zhang Y, Yan C, Yang M, Wang Z, Li W, Li F, Wang W, Yang Y, Li X, Tang Z., Free PMC Article | 03/15/2023 |
| Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4. | Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4.
Kim SM, Song GY, Shim A, Lee JH, Eom CB, Liu C, Yang YM, Seki E., Free PMC Article | 07/16/2022 |
| MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease. | MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease.
Mostofa MG, Tran M, Gilling S, Lee G, Fraher O, Jin L, Kang H, Park YK, Lee JY, Wang L, Shin DJ., Free PMC Article | 07/2/2022 |
| Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells. | Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells.
Ottaviani L, Juni RP, de Abreu RC, Sansonetti M, Sampaio-Pinto V, Halkein J, Hegenbarth JC, Ring N, Knoops K, Kocken JMM, Jesus C, Ernault AC, El Azzouzi H, Rühle F, Olieslagers S, Fernandes H, Ferreira L, Braga L, Stoll M, Nascimento DS, de Windt LJ, da Costa Martins PA., Free PMC Article | 06/11/2022 |
| MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice. | MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice.
Wu G, Zhang D, Yang L, Wu Q, Yuan L. | 05/21/2022 |
| MiR-200c-3p targets SESN1 and represses the IL-6/AKT loop to prevent cholangiocyte activation and cholestatic liver fibrosis. | MiR-200c-3p targets SESN1 and represses the IL-6/AKT loop to prevent cholangiocyte activation and cholestatic liver fibrosis.
Song Y, Tran M, Wang L, Shin DJ, Wu J., Free PMC Article | 05/14/2022 |
| Necdin, one of the important pathway proteins in the regulation of osteosarcoma progression by microRNA-200c. | Necdin, one of the important pathway proteins in the regulation of osteosarcoma progression by microRNA-200c.
Li J, Wu Z, Wang J, Wu T, Shen Z, Zhang L, Lv J, Bai J, Feng Y., Free PMC Article | 05/7/2022 |
| miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3gamma in early stage of 5xFAD mouse model of Alzheimer's disease. | miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease.
Park H, Lee YB, Chang KA., Free PMC Article | 04/30/2022 |
| MiR-200c-3p Regulates DUSP1/MAPK Pathway in the Nonalcoholic Fatty Liver After Laparoscopic Sleeve Gastrectomy. | MiR-200c-3p Regulates DUSP1/MAPK Pathway in the Nonalcoholic Fatty Liver After Laparoscopic Sleeve Gastrectomy.
Zhang TT, Wang Y, Zhang XW, Yang KY, Miao XQ, Zhao GH., Free PMC Article | 04/30/2022 |
| miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts. | miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts.
Xue B, Chuang CH, Prosser HM, Fuziwara CS, Chan C, Sahasrabudhe N, Kühn M, Wu Y, Chen J, Biton A, Chen C, Wilkinson JE, McManus MT, Bradley A, Winslow MM, Su B, He L., Free PMC Article | 04/9/2022 |
| MicroRNA-200c/429 mediated regulation of Zeb1 augments N-Cadherin in mouse cardiac mesenchymal cells. | MicroRNA-200c/429 mediated regulation of Zeb1 augments N-Cadherin in mouse cardiac mesenchymal cells.
Nath AV, Ajit S, Sekar AJ, P R AK, Muthusamy S. | 04/9/2022 |
| The miR-200-Zeb1 axis regulates key aspects of beta-cell function and survival in vivo. | The miR-200-Zeb1 axis regulates key aspects of β-cell function and survival in vivo.
Title AC, Silva PN, Godbersen S, Hasenöhrl L, Stoffel M., Free PMC Article | 03/26/2022 |
| Expression of miR-200c corresponds with increased reactive oxygen species and hypoxia markers after transient focal ischemia in mice. | Expression of miR-200c corresponds with increased reactive oxygen species and hypoxia markers after transient focal ischemia in mice.
Arvola O, Griffiths B, Rao A, Xu L, Pastroudis IA, Stary CM., Free PMC Article | 02/5/2022 |
| Ectopic activation of the miR-200c-EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy. | Ectopic activation of the miR-200c-EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy.
Zhang M, Zhao Z, Pritykin Y, Hannum M, Scott AC, Kuo F, Sanghvi V, Chan TA, Seshan V, Wendel HG, Schietinger A, Sadelain M, Huse M., Free PMC Article | 11/6/2021 |
| miR-200c-3p Regulates Epitelial-to-Mesenchymal Transition in Epicardial Mesothelial Cells by Targeting Epicardial Follistatin-Related Protein 1. | miR-200c-3p Regulates Epitelial-to-Mesenchymal Transition in Epicardial Mesothelial Cells by Targeting Epicardial Follistatin-Related Protein 1.
Pontemezzo E, Foglio E, Vernucci E, Magenta A, D'Agostino M, Sileno S, Astanina E, Bussolino F, Pellegrini L, Germani A, Russo MA, Limana F., Free PMC Article | 06/19/2021 |
| MicroRNA-200b/c-3p regulate epithelial plasticity and inhibit cutaneous wound healing by modulating TGF-beta-mediated RAC1 signaling. | MicroRNA-200b/c-3p regulate epithelial plasticity and inhibit cutaneous wound healing by modulating TGF-β-mediated RAC1 signaling.
Tang H, Wang X, Zhang M, Yan Y, Huang S, Ji J, Xu J, Zhang Y, Cai Y, Yang B, Lan W, Huang M, Zhang L., Free PMC Article | 05/22/2021 |
| Our study is the first to show that fascin-1 plays a critical role in renal fibrosis; MiR-200b/c family could inhibit renal fibrosis through modulating EMT process by directly targeting fascin-1/CD44 axis | MiR-200b/c family inhibits renal fibrosis through modulating epithelial-to-mesenchymal transition via targeting fascin-1/CD44 axis.
Fu H, Gu YH, Yang YN, Liao S, Wang GH. | 06/6/2020 |
| miR-200c inhibition repressed the production of proinflammatory cytokines (TGF-beta, TNF-alpha, and IL-1alpha) via inhibiting NF-kappaB and Smad2 activation in NHKs exposed to IR. | miR-200c Modulates the Pathogenesis of Radiation-Induced Oral Mucositis.
Tao J, Fan M, Zhou D, Hong Y, Zhang J, Liu H, Sharma S, Wang G, Dong Q., Free PMC Article | 02/22/2020 |
| The miR-200c/141 cluster regulated breast cancer stem cells heterogeneity and promoted the epithelial-mesenchymal transformation-like breast cancer stem cells generation, which resulted in increased tumor metastasis and inhibited tumor growth by directly upregulating the target gene homeodomain-interacting protein kinase 1 (HIPK1) and sequential beta-catenin activation. | miR-200c/141 Regulates Breast Cancer Stem Cell Heterogeneity via Targeting HIPK1/β-Catenin Axis.
Liu B, Du R, Zhou L, Xu J, Chen S, Chen J, Yang X, Liu DX, Shao ZM, Zhang L, Yu Z, Xie N, Guan JL, Liu S., Free PMC Article | 09/7/2019 |
| We identified miR-200 family members, in particular miR- 200c, as CD-enriched miRNAs and show that downregulation of these miRNAs is associated with partial EMT in the CDs. | Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.
Hajarnis S, Yheskel M, Williams D, Brefort T, Glaudemans B, Debaix H, Baum M, Devuyst O, Patel V., Free PMC Article | 07/13/2019 |
| disrupting the in vivo regulation of Zeb1 by miR-200c is sufficient to drive epithelial-to-mesenchymal transition, thus highlighting the importance of this axis in tumor progression and invasion. | Genetic dissection of the miR-200-Zeb1 axis reveals its importance in tumor differentiation and invasion.
Title AC, Hong SJ, Pires ND, Hasenöhrl L, Godbersen S, Stokar-Regenscheit N, Bartel DP, Stoffel M., Free PMC Article | 04/27/2019 |
| In the development of LPS-induced early pulmonary fibrosis, miR-200b/c was downregulated, whereas ZEB1/2 was upregulated; miR-200b/c exerts a protective effect by targeting ZEB1/2. | miR-200b/c attenuates lipopolysaccharide-induced early pulmonary fibrosis by targeting ZEB1/2 via p38 MAPK and TGF-β/smad3 signaling pathways.
Cao Y, Liu Y, Ping F, Yi L, Zeng Z, Li Y. | 02/9/2019 |
| these results indicate that miR-21a negatively modulates two tumor suppressor genes, miR-200c and PTEN, thereby promoting M2 macrophage transformation | miR-21a negatively modulates tumor suppressor genes PTEN and miR-200c and further promotes the transformation of M2 macrophages.
Li N, Qin JF, Han X, Jin FJ, Zhang JH, Lan L, Wang Y. | 12/22/2018 |
| miR-200c might be responsible for muscle wasting and myotube loss, most probably via a p66Shc-dependent mechanism in a pathological disease such as Duchenne muscular dystrophy. | Role of miR-200c in Myogenic Differentiation Impairment via p66Shc: Implication in Skeletal Muscle Regeneration of Dystrophic mdx Mice.
D'Agostino M, Torcinaro A, Madaro L, Marchetti L, Sileno S, Beji S, Salis C, Proietti D, Imeneo G, C Capogrossi M, De Santa F, Magenta A., Free PMC Article | 09/22/2018 |