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    Mir98 microRNA 98 [ Mus musculus (house mouse) ]

    Gene ID: 723947, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MicroRNA 98-5p Overexpression Contributes to Delayed Fracture Healing via Targeting BMP-2.

    MicroRNA 98-5p Overexpression Contributes to Delayed Fracture Healing via Targeting BMP-2.
    Zhang YB, Guo XQ, Wang GG, Pu HB.

    06/5/2024
    Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis.

    Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis.
    Deng B, Zhao Y, Liu J., Free PMC Article

    03/26/2024
    KNOCKDOWN OF CIRC_0001379 ATTENUATES HYPOXIA/REOXYGENATION-INDUCED CARDIOMYOCYTE APOPTOSIS AND INFLAMMATORY RESPONSE BY MIR-98-5P/SOX6 AXIS.

    KNOCKDOWN OF CIRC_0001379 ATTENUATES HYPOXIA/REOXYGENATION-INDUCED CARDIOMYOCYTE APOPTOSIS AND INFLAMMATORY RESPONSE BY MIR-98-5P/SOX6 AXIS.
    Wang K, Wang H, Zhang Q, Liu F.

    09/18/2023
    MicroRNA-98 inhibition accelerates the development of atherosclerosis via regulation of dysfunction of endothelial cell.

    MicroRNA-98 inhibition accelerates the development of atherosclerosis via regulation of dysfunction of endothelial cell.
    Yu H, Cao H, Yu H.

    08/25/2023
    MiR-98-3p regulates ovarian granulosa cell proliferation and apoptosis in polycystic ovary syndrome by targeting YY1.

    MiR-98-3p regulates ovarian granulosa cell proliferation and apoptosis in polycystic ovary syndrome by targeting YY1.
    Hu M, Gao T, Du Y.

    03/12/2022
    M1 macrophage-derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA-98/DUSP1/JNK axis.

    M1 macrophage-derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA-98/DUSP1/JNK axis.
    Yu L, Hu M, Cui X, Bao D, Luo Z, Li D, Li L, Liu N, Wu Y, Luo X, Ma Y.

    03/5/2022
    miR-98-5p plays a critical role in depression and antidepressant effect of ketamine.

    miR-98-5p plays a critical role in depression and antidepressant effect of ketamine.
    Huang C, Wang Y, Wu Z, Xu J, Zhou L, Wang D, Yang L, Zhu B, Chen G, Liu C, Yang C., Free PMC Article

    10/16/2021
    Long Noncoding RNA X-Inactive Specific Transcript Regulates Neuronal Cell Apoptosis in Ischemic Stroke Through miR-98/BACH1 Axis.

    Long Noncoding RNA X-Inactive Specific Transcript Regulates Neuronal Cell Apoptosis in Ischemic Stroke Through miR-98/BACH1 Axis.
    Weng S, Wang S, Jiang J.

    07/31/2021
    Post-transcriptional regulation of alpha7 nAChR expression by miR-98-5p modulates cognition and neuroinflammation in an animal model of Alzheimer's disease.

    Post-transcriptional regulation of α7 nAChR expression by miR-98-5p modulates cognition and neuroinflammation in an animal model of Alzheimer's disease.
    Song C, Shi J, Xu J, Zhao L, Zhang Y, Huang W, Qiu Y, Zhang R, Chen H, Wang H.

    07/24/2021
    LncRNA TTTY15 knockdown alleviates H2O2-stimulated myocardial cell injury by regulating the miR-98-5p/CRP pathway.

    LncRNA TTTY15 knockdown alleviates H(2)O(2)-stimulated myocardial cell injury by regulating the miR-98-5p/CRP pathway.
    Ma R, Gao L, Liu Y, Du P, Chen X, Li G.

    07/17/2021
    miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.

    miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
    Yu S, Zhai J, Yu J, Yang Q, Yang J.

    07/10/2021
    miR-98 reduces endothelial dysfunction by protecting blood-brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model.

    miR-98 reduces endothelial dysfunction by protecting blood-brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model.
    Bernstein DL, Zuluaga-Ramirez V, Gajghate S, Reichenbach NL, Polyak B, Persidsky Y, Rom S., Free PMC Article

    03/20/2021
    MiR-98-5p expression inhibits polarization of macrophages to an M2 phenotype by targeting Trib1 in inflammatory bowel disease.

    MiR-98-5p expression inhibits polarization of macrophages to an M2 phenotype by targeting Trib1 in inflammatory bowel disease.
    Peng Y, Wang Q, Yang W, Yang Q, Pei Y, Zhang W.

    02/20/2021
    overexpression of miR-98-5p inhibited Bach1 expression while suppression of miR-98-5p promoted Bach1 expression in neurons.

    MicroRNA-98-5p ameliorates oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by inhibiting Bach1 and promoting Nrf2/ARE signaling.
    Sun X, Li X, Ma S, Guo Y, Li Y.

    05/18/2019
    MicroRNA-98 regulates hepatic cholesterol metabolism by targeting SREBP2

    MicroRNA-98 regulates hepatic cholesterol metabolism via targeting sterol regulatory element-binding protein 2.
    Geng C, Dong T, Jin W, Yu B, Yin F, Peng F, Chen G, Ji C, Ding F.

    03/30/2019
    miR98 reduced the production of Abeta and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in Alzheimer's disease mice.

    MicroRNA-98 reduces amyloid β-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer's disease mice.
    Chen FZ, Zhao Y, Chen HZ., Free PMC Article

    03/2/2019
    Reduced expression of miR-98 may relate to LOX-1 expression and foam cell formation and lipid accumulation in aortas of ApoE(-/-) mice.

    MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1.
    Dai Y, Wu X, Dai D, Li J, Mehta JL., Free PMC Article

    10/13/2018
    The miR985p overexpression decreased the protein levels of CKIP1 and inhibition of miR985p increased the protein levels of CKIP1.

    miR‑98‑5p promotes osteoblast differentiation in MC3T3‑E1 cells by targeting CKIP‑1.
    Liu Q, Guo Y, Wang Y, Zou X, Yan Z.

    08/18/2018
    the present study confirmed that miR98 targeted the 3'untranslated region of Bcl2. In conclusion, miRNAcoordinated regulation of apoptosisassociated protein expression has been identified in Osteoarthritis chondrocytes following IL1beta induction.

    Altered expression of microRNA-98 in IL-1β-induced cartilage degradation and its role in chondrocyte apoptosis.
    Wang J, Chen L, Jin S, Lin J, Zheng H, Zhang H, Fan H, He F, Ma S, Li Q., Free PMC Article

    04/28/2018
    expression level of miR-98, which can regulate Caspase-3, was significantly decreased. Huwe1, the host gene of miR-98, was positively associated with miR-98 expression after Silica NP exposure

    miR-98 and its host gene Huwe1 target Caspase-3 in Silica nanoparticles-treated male germ cells.
    Xu B, Mao Z, Ji X, Yao M, Chen M, Zhang X, Hang B, Liu Y, Tang W, Tang Q, Xia Y., Free PMC Article

    08/27/2016
    PPARgamma regulates miR-98 to modulate ET-1 expression and pulmonary endothelial cell proliferation in pulmonary hypertension.

    Peroxisome Proliferator-Activated Receptor γ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling.
    Kang BY, Park KK, Kleinhenz JM, Murphy TC, Green DE, Bijli KM, Yeligar SM, Carthan KA, Searles CD, Sutliff RL, Hart CM., Free PMC Article

    05/7/2016
    miR-98 reduces melanoma metastasis and increases survival in part by reducing IL-6 levels.

    miR-98 suppresses melanoma metastasis through a negative feedback loop with its target gene IL-6.
    Li F, Li XJ, Qiao L, Shi F, Liu W, Li Y, Dang YP, Gu WJ, Wang XG, Liu W., Free PMC Article

    02/21/2015
    microRNA-98 is a therapeutic target inhibiting prostate cancer growth and a biomarker induced by vitamin D

    Identification of microRNA-98 as a therapeutic target inhibiting prostate cancer growth and a biomarker induced by vitamin D.
    Ting HJ, Messing J, Yasmin-Karim S, Lee YF., Free PMC Article

    03/2/2013
    miR-98-mediated posttranscriptional control could potentially be involved in fine tuning the critical level of IL-10 production in endotoxin tolerance.

    MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation.
    Liu Y, Chen Q, Song Y, Lai L, Wang J, Yu H, Cao X, Wang Q.

    09/10/2011
    Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7.

    Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7.
    Yang Y, Ago T, Zhai P, Abdellatif M, Sadoshima J., Free PMC Article

    04/16/2011
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