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    TYRO3 TYRO3 protein tyrosine kinase [ Homo sapiens (human) ]

    Gene ID: 7301, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    TYRO3 and EPHA2 Expression Are Dysregulated in Breast Cancer.

    TYRO3 and EPHA2 Expression Are Dysregulated in Breast Cancer.
    de Aguiar ACF, Ferreira NCFL, Borba MACSM, Filho DLF, Leitão GM, Mattos LA, Filho JLL, Martins DBG.

    10/2/2024
    Tyro3 receptor tyrosine kinase contributes to pathogenic phenotypes of fibroblast-like synoviocytes in rheumatoid arthritis and disturbs immune cell balance in experimental arthritis.

    Tyro3 receptor tyrosine kinase contributes to pathogenic phenotypes of fibroblast-like synoviocytes in rheumatoid arthritis and disturbs immune cell balance in experimental arthritis.
    Wang Z, Zhao Z, Li Z, Xu L, Li H, Zhu H, Cheng G, Yao R, Pei W, Liang R, Liang R, Ye H, Jiang S, Niu H, Sun X, Su Y.

    05/3/2024
    Expression and clinical association of MFG-E8 and TAM receptors in diabetic patients with different stages of microvascular complication: An experimental study.

    Expression and clinical association of MFG-E8 and TAM receptors in diabetic patients with different stages of microvascular complication: An experimental study.
    Xiong Y, Wang B, Jiao J, Tang M, Li K, Jiang R, Huang W., Free PMC Article

    11/28/2023
    Overexpression of TYRO3 indicates poor prognosis and induces gastric cancer progression via AKT-mTOR pathway.

    Overexpression of TYRO3 indicates poor prognosis and induces gastric cancer progression via AKT-mTOR pathway.
    Wang J, Cheng Z, Dai D, Li H, Shao X, Xu M.

    08/22/2023
    TYRO3 promotes tumorigenesis and drug resistance in colorectal cancer by enhancing the epithelial-mesenchymal transition process.

    TYRO3 promotes tumorigenesis and drug resistance in colorectal cancer by enhancing the epithelial-mesenchymal transition process.
    Shao X, Sun Y, Zhong K, Gu J, Yu Y, Hu T, Kuai X, Xing Y., Free PMC Article

    05/13/2023
    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.

    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.
    Hsu PL, Chien CW, Tang YA, Lin BW, Lin SC, Lin YS, Chen SY, Sun HS, Tsai SJ., Free PMC Article

    04/14/2023
    TYRO3 agonist as therapy for glomerular disease.

    TYRO3 agonist as therapy for glomerular disease.
    Zhong F, Cai H, Fu J, Sun Z, Li Z, Bauman D, Wang L, Das B, Lee K, He JC., Free PMC Article

    01/21/2023
    MiR-140-3p directly targets Tyro3 to regulate OGD/R-induced neuronal injury through the PI3K/Akt pathway.

    MiR-140-3p directly targets Tyro3 to regulate OGD/R-induced neuronal injury through the PI3K/Akt pathway.
    Zhang Y, Su Q, Xia W, Jia K, Meng D, Wang X, Ni X, Su Z.

    12/24/2022
    Circ_0000467 Exerts an Oncogenic Role in Colorectal Cancer via miR-330-5p-Dependent Regulation of TYRO3.

    Circ_0000467 Exerts an Oncogenic Role in Colorectal Cancer via miR-330-5p-Dependent Regulation of TYRO3.
    Huang Y, Chen Z, Zhou X, Huang H.

    09/24/2022
    TYRO3 Knockdown Suppresses the Growth of Myeloid Leukaemia Cells.

    TYRO3 Knockdown Suppresses the Growth of Myeloid Leukaemia Cells.
    Saito T, Itoh M, Tohda S.

    04/9/2022
    Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target.

    Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target.
    Sainaghi PP, Bellan M, Nerviani A., Free PMC Article

    10/30/2021
    TAM and TIM receptors mRNA expression in Zika virus infected placentas.

    TAM and TIM receptors mRNA expression in Zika virus infected placentas.
    Nobrega GM, Samogim AP, Parise PL, Venceslau EM, Guida JPS, Japecanga RR, Amorim MR, Toledo-Teixeira DA, Forato J, Consonni SR, Costa ML, Proenca-Modena JL, Zika-Unicamp Network.

    10/23/2021
    TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis.

    TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis.
    Jiang Z, Lim SO, Yan M, Hsu JL, Yao J, Wei Y, Chang SS, Yamaguchi H, Lee HH, Ke B, Hsu JM, Chan LC, Hortobagyi GN, Yang L, Lin C, Yu D, Hung MC., Free PMC Article

    10/2/2021
    Immunological role of TAM receptors in the cancer microenvironment.

    Immunological role of TAM receptors in the cancer microenvironment.
    Gadiyar V, Patel G, Davra V.

    09/4/2021
    Post-translational modifications of the ligands: Requirement for TAM receptor activation.

    Post-translational modifications of the ligands: Requirement for TAM receptor activation.
    Geng K.

    09/4/2021
    TAM receptors and their ligand-mediated activation: Role in atherosclerosis.

    TAM receptors and their ligand-mediated activation: Role in atherosclerosis.
    Cai B, Kasikara C., Free PMC Article

    09/4/2021
    Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair.

    Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair.
    Ranta A, Kumar S.

    09/4/2021
    Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis.

    Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis.
    Vullings J, Vago JP, Waterborg CEJ, Thurlings RM, Koenders MI, van Lent PLEM, van der Kraan PM, Amaral FA, van de Loo FAJ., Free PMC Article

    07/10/2021
    Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells.

    Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells.
    Al Kafri N, Hafizi S., Free PMC Article

    04/17/2021
    TYRO3 facilitates cell growth and metastasis via activation of the Wnt/beta-catenin signaling pathway in human gastric cancer cells.

    TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells.
    Chen D, Liu Q, Cao G, Zhang W., Free PMC Article

    01/16/2021
    Functional Genomics Identifies Hepatitis-Induced STAT3-TYRO3-STAT3 Signaling as a Potential Therapeutic Target of Hepatoma.

    Functional Genomics Identifies Hepatitis-Induced STAT3-TYRO3-STAT3 Signaling as a Potential Therapeutic Target of Hepatoma.
    Tsai CL, Chang JS, Yu MC, Lee CH, Chen TC, Chuang WY, Kuo WL, Lin CC, Lin SM, Hsieh SY.

    01/9/2021
    Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus.

    Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus.
    Liphaus BL, Lima L, Palmeira P, Silva CA, Goldenstein-Schainberg C, Carneiro-Sampaio M.

    11/21/2020
    TYRO3 Truncation Resulting From a t(10;15)(p11;q15) Chromosomal Translocation in Pediatric Acute Myeloid Leukemia.

    TYRO3 Truncation Resulting From a t(10;15)(p11;q15) Chromosomal Translocation in Pediatric Acute Myeloid Leukemia.
    Brunetti M, Zeller B, Tierens A, Heim S, Micci F, Panagopoulos I.

    11/21/2020
    Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer.

    Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer.
    Uejima C, Morimoto M, Yamamoto M, Hara K, Miyauchi W, Sugezawa K, Tada Y, Tanio A, Kihara K, Matsunaga T, Tokuyasu N, Sakamoto T, Honjo S, Umekita Y, Fujiwara Y.

    10/10/2020
    New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis.

    New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis.
    Pagani S, Bellan M, Mauro D, Castello LM, Avanzi GC, Lewis MJ, Sainaghi PP, Pitzalis C, Nerviani A., Free PMC Article

    10/10/2020
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