| miR-495 promotes intestinal epithelial cell apoptosis through downregulation of Sphingosine-1-phosphate. | miR-495 promotes intestinal epithelial cell apoptosis through downregulation of Sphingosine-1-phosphate.
Li R, Cairns C, Yu TX, Jaladanki R, Dodson CM, Chung HK, Xiao L, Wang JY, Turner DJ., Free PMC Article | 09/12/2024 |
| MicroRNA-495 downregulates AQP1 and facilitates proliferation and differentiation of osteoblasts in mice with tibial fracture through activation of p38 MAPK signaling pathway. | MicroRNA-495 downregulates AQP1 and facilitates proliferation and differentiation of osteoblasts in mice with tibial fracture through activation of p38 MAPK signaling pathway.
Zhu L, Lin ZW, Wang G, Zhang H, Liu B, Xu QJ., Free PMC Article | 10/31/2020 |
| FTO was proved to be a direct target gene of miR-495. | MiR-495 regulates macrophage M1/M2 polarization and insulin resistance in high-fat diet-fed mice via targeting FTO.
Hu F, Tong J, Deng B, Zheng J, Lu C. | 05/16/2020 |
| overexpressed miR-495 directly promotes proliferation while simultaneously inhibiting apoptosis of femoral vein (FV) tissues endothelial cells, alleviating FV thrombosis by inhibiting IL1R1 via suppression of TLR4 signaling pathway. | Effect of miR-495 on lower extremity deep vein thrombosis through the TLR4 signaling pathway by regulation of IL1R1.
Tang KC, Yang ZP, Zeng Q, Wang J, Guo F, Zhao Y., Free PMC Article | 07/27/2019 |
| a circuitry in which the upregulation of miR-409-3p and miR-495-3p, belonging to a brain-specific miRNA subcluster implicated in several neurodevelopmental disorders, produced the downregulation of Gria2, is reported. | A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.
Capauto D, Colantoni A, Lu L, Santini T, Peruzzi G, Biscarini S, Morlando M, Shneider NA, Caffarelli E, Laneve P, Bozzoni I., Free PMC Article | 12/22/2018 |
| The miR-495 reduced the mRNA and protein levels of NLRP3, TNF-alpha, IL-1beta, IL-18 and caspase-1, inhibited cell apoptosis and decreased cells at the G0/G1 phase while improving cell proliferation and increasing cells at the S phase. | MicroRNA-495 Ameliorates Cardiac Microvascular Endothelial Cell Injury and Inflammatory Reaction by Suppressing the NLRP3 Inflammasome Signaling Pathway.
Zhou T, Xiang DK, Li SN, Yang LH, Gao LF, Feng C. | 09/22/2018 |
| that miR-495 improves the intestinal mucosal barrier function by targeting STAT3 through inhibiting the JAK/STAT3 signaling pathway in ulcerative colitis mice | Overexpression of microRNA-495 improves the intestinal mucosal barrier function by targeting STAT3 via inhibition of the JAK/STAT3 signaling pathway in a mouse model of ulcerative colitis.
Chu XQ, Wang J, Chen GX, Zhang GQ, Zhang DY, Cai YY. | 09/1/2018 |
| MiR-495 inhibits new bone regeneration via targeting high mobility group AT-Hook 2 (HMGA2). | MicroRNA-495 Inhibits New Bone Regeneration via Targeting High Mobility Group AT-Hook 2 (HMGA2).
Tian Z, Zhou H, Xu Y, Bai J., Free PMC Article | 06/2/2018 |
| Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis. | Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis.
Welten SMJ, de Jong RCM, Wezel A, de Vries MR, Boonstra MC, Parma L, Jukema JW, van der Sluis TC, Arens R, Bot I, Agrawal S, Quax PHA, Nossent AY. | 03/17/2018 |
| TSPAN12 promotes chemoresistance and proliferation of small cell lung carcinoma under the regulation of miR-495. | TSPAN12 promotes chemoresistance and proliferation of SCLC under the regulation of miR-495.
Ye M, Wei T, Wang Q, Sun Y, Tang R, Guo L, Zhu W. | 06/10/2017 |
| miR-495 targets ATG3 and regulates its protein levels under starvation conditions. miR-495 also inhibits starvation-induced autophagy by decreasing the number of autophagosomes. | MicroRNA-495 regulates starvation-induced autophagy by targeting ATG3.
Li W, Yang Y, Hou X, Zhuang H, Wu Z, Li Z, Guo R, Chen H, Lin C, Zhong W, Chen Y, Wu K, Zhang L, Feng D. | 08/13/2016 |
| expression of miR-410 and miR-495 processed from the Gtl2-Dio3 locus in various cardiomyopathies, was examined. | miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy.
Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ., Free PMC Article | 08/13/2016 |
| miR-410 and miR-495 are among a growing number of miRNAs that have the ability to potently stimulate neonatal cardiomyocyte proliferation. | MicroRNAs in the Myocyte Enhancer Factor 2 (MEF2)-regulated Gtl2-Dio3 Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2.
Clark AL, Naya FJ., Free PMC Article | 12/19/2015 |
| Authors identified Dnmt3a as a functional target of miR-495 and showed that endogenous miR-495 repressed the expression of Dnmt3a in mESCs. | MiR-495 suppresses mesendoderm differentiation of mouse embryonic stem cells via the direct targeting of Dnmt3a.
Yang D, Wang G, Zhu S, Liu Q, Wei T, Leng Y, Duan T, Kang J. | 01/10/2015 |
| Let-7b, miR-495, and their targets constitute a gene network that is required to establish and maintain pancreatic acinar cell differentiation. Let-7b and miR-495 repress HNF6 and are expressed in developing acini. | Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.
Prévot PP, Augereau C, Simion A, Van den Steen G, Dauguet N, Lemaigre FP, Jacquemin P. | 11/16/2013 |
| These results indicate that the expression of HNF-6 and OC-2 regulators of liver and pancreas development is modulated by miR-495 and miR-218. | MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2.
Simion A, Laudadio I, Prévot PP, Raynaud P, Lemaigre FP, Jacquemin P. | 03/22/2010 |