| CSPalpha may modulate fusion pore dynamics in a phosphorylation-dependent manner. | Phosphomimetic mutation of cysteine string protein-α increases the rate of regulated exocytosis by modulating fusion pore dynamics in PC12 cells.
Chiang N, Hsiao YT, Yang HJ, Lin YC, Lu JC, Wang CT., Free PMC Article | 10/17/2015 |
| both the J-domain and the linker domain of CSP1 are necessary to function in an important role in acinar cell exocytosis | Characterization of cysteine string protein in rat parotid acinar cells.
Shimomura H, Imai A, Nashida T. | 11/16/2013 |
| a biochemical link between Hsp40 expression and Abeta(42) proteostasis that is cell specific | Cell line specific modulation of extracellular aβ42 by Hsp40.
Carnini A, Scott LO, Ahrendt E, Proft J, Winkfein RJ, Kim SW, Colicos MA, Braun JE., Free PMC Article | 11/3/2012 |
| Establish a role for CSP-alpha in regulating digestive enzyme secretion and suggest that CSP-alpha and Hsc70 modulate specific soluble N-ethylmaleimide-sensitive attachment receptor interactions necessary for exocytosis. | Functional role of J domain of cysteine string protein in Ca2+-dependent secretion from acinar cells.
Weng N, Baumler MD, Thomas DD, Falkowski MA, Swayne LA, Braun JE, Groblewski GE., Free PMC Article | 01/21/2010 |
| palmitoylation of CSP is enhanced specifically by co-expression of the Golgi-localized palmitoyl transferases DHHC3, DHHC7, DHHC15, or DHHC17 | Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein.
Greaves J, Salaun C, Fukata Y, Fukata M, Chamberlain LH., Free PMC Article | 01/21/2010 |
| CSPalpha activity is subject to regulation by factors that alter Hsc70 distribution and translocation within the cell | The CSPalpha/G protein complex in PC12 cells.
Bai L, Swayne LA, Braun JE. | 01/21/2010 |
| cysteine string protein binds to a brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein | A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein.
Tobaben S, Varoqueaux F, Brose N, Stahl B, Meyer G. | 01/21/2010 |
| phosphorylation-dependent interaction with synaptotagmin I | Phosphorylation-dependent interaction of the synaptic vesicle proteins cysteine string protein and synaptotagmin I.
Evans GJ, Morgan A., Free PMC Article | 01/21/2010 |
| A novel alphaGDI complex from synaptic membranes contains three chaperone components: Hsp90, Hsc70 and cysteine string protein (CSP). The complex is dissociated in response to Ca(2+)-induced neurotransmitter release. | Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex.
Sakisaka T, Meerlo T, Matteson J, Plutner H, Balch WE., Free PMC Article | 01/21/2010 |
| Proportion of the phosphorylated protein varies between distinct brain regions and also exhibits developmental regulation. | Phosphorylation of cysteine string protein in the brain: developmental, regional and synaptic specificity.
Evans GJ, Morgan A. | 01/21/2010 |
| Data suggest that cysteine string protein self-interactions may be an important consideration for current working models of CSP chaperone activity at the synapse. | Oligomerization characteristics of cysteine string protein.
Swayne LA, Blattler C, Kay JG, Braun JE. | 01/21/2010 |
| distinct binding sites of CSP can play a role in modulating G protein function and G protein inhibition of calcium channels | Molecular determinants of cysteine string protein modulation of N-type calcium channels.
Miller LC, Swayne LA, Kay JG, Feng ZP, Jarvis SE, Zamponi GW, Braun JE. | 01/21/2010 |
| Cysteine string protein inhibits N-type calcium channels, but is blocked by mutant huntingtin | Cysteine string protein (CSP) inhibition of N-type calcium channels is blocked by mutant huntingtin.
Miller LC, Swayne LA, Chen L, Feng ZP, Wacker JL, Muchowski PJ, Zamponi GW, Braun JE. | 01/21/2010 |
| The presence of cysteine-string protein in synaptic vesicles of inner hair cells and its synchronized expression with the appearance of cochlear potentials suggests that this protein mediates sound-evoked glutamate release by inner hair cells. | Cysteine-string protein in inner hair cells of the organ of Corti: synaptic expression and upregulation at the onset of hearing.
Eybalin M, Renard N, Aure F, Safieddine S. | 01/21/2010 |