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    Mtpn myotrophin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 79215, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    after internalization into myocytes, myotrophin cotranslocates into the nucleus with p65 to stimulate myocyte growth.

    Nuclear co-translocation of myotrophin and p65 stimulates myocyte growth. Regulation by myotrophin hairpin loops.
    Das B, Gupta S, Vasanji A, Xu Z, Misra S, Sen S., Free PMC Article

    01/21/2010
    characterisation of the small ankyrin repeat protein myotrophin

    Biophysical characterisation of the small ankyrin repeat protein myotrophin.
    Lowe AR, Itzhaki LS.

    01/21/2010
    Data strongly suggest that myotrophin appears to be a candidate gene for cardiac hypertrophy and heart failure.

    Characterization and functional significance of myotrophin: a gene with multiple transcripts.
    Adhikary G, Gupta S, Sil P, Saad Y, Sen S.

    01/21/2010
    role in controlling catecholamine secretion in PC12D cells

    V-1, a catecholamine biosynthesis regulatory protein, positively controls catecholamine secretion in PC12D cells.
    Yamakuni T, Yamamoto T, Ishida Y, Yamamoto H, Song SY, Adachi E, Hiwatashi Y, Ohizumi Y.

    01/21/2010
    regulates catecholamine biosynthesis in a catecholaminergic phenotype-dependent manner

    Glucocorticoid inhibits expression of V-1, a catecholamine biosynthesis regulatory protein, in cultured adrenal medullary cells.
    Hiwatashi Y, Kurahashi Y, Hatada R, Ueno S, Honma T, Yanagihara N, Yanase H, Iwanaga T, Ohizumi Y, Yamakuni T.

    01/21/2010
    V-1 expression is increased by hypertension in DS rat atrium.

    Expression of V-1, a novel catecholamine biosynthesis regulatory protein, is enhanced by hypertension in atrial myocytes of Dahl salt-sensitive rats.
    Yamakuni T, Hashimoto M, Sakagami H, Yamamoto T, Kobayashi M, Fujii Y, Yamamoto H, Rohra DK, Hiwatashi Y, Honma T, Kondo H, Shido O, Ohizumi Y.

    01/21/2010
    V-1 plays a role in prenatal muscle differentiation and postnatal muscle regeneration.

    Down-regulation of an ankyrin repeat-containing protein, V-1, during skeletal muscle differentiation and its re-expression in the regenerative process of muscular dystrophy.
    Furukawa Y, Hashimoto N, Yamakuni T, Ishida Y, Kato C, Ogashiwa M, Kobayashi M, Kobayashi T, Nonaka I, Mizusawa H, Song SY.

    01/21/2010
    stretching of cardiac myocytes by pressure or volume caused significant increase in the transcript levels of myotrophin , which in turn is responsible for the initiation process of myocardial hypertrophy

    Regulation of myotrophin gene by pressure overload and stretch.
    Sil P, Gupta S, Young D, Sen S.

    01/21/2010
    expressed transiently during murine cerebellar development, regulates actin polymerization via interaction with capping protein

    V-1, a protein expressed transiently during murine cerebellar development, regulates actin polymerization via interaction with capping protein.
    Taoka M, Ichimura T, Wakamiya-Tsuruta A, Kubota Y, Araki T, Obinata T, Isobe T.

    01/21/2010
    Results suggest that myotrophin V1 is a predominantly cytosolic protein that could regulate the NFkappa-beta mediated transcription process.

    Myotrophin/V-1 does not act as an extracellular signal to induce myocyte hypertrophy.
    Knuefermann P, Shi SP, Chen P, Sakata Y, Baumgarten G, Sivasubramanian N., Free PMC Article

    01/21/2010
    Equilibrium folding and stability of myotrophin: a model ankyrin repeat protein.

    Equilibrium folding and stability of myotrophin: a model ankyrin repeat protein.
    Mosavi LK, Williams S, Peng Zy ZY.

    01/21/2010
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