| Filamentous nestin and nonmuscle myosin IIB are associated with a migratory phenotype in neonatal rat cardiomyocytes. | Filamentous nestin and nonmuscle myosin IIB are associated with a migratory phenotype in neonatal rat cardiomyocytes.
Bergeron A, Brezai A, Shukr R, Villeneuve L, Allen BG, Qureshi WMS, Hentges KE, Calderone A. | 09/11/2021 |
| Study suggests that NMIIB remains constitutively active in support of methamphetamine associations, continuing to drive actin polymerization, such that memories associated with methamphetamine can be selectively targeted without the need for retrieval days to weeks after learning | Nonmuscle myosin IIB as a therapeutic target for the prevention of relapse to methamphetamine use.
Young EJ, Blouin AM, Briggs SB, Sillivan SE, Lin L, Cameron MD, Rumbaugh G, Miller CA., Free PMC Article | 01/14/2017 |
| NM II maintains proper morphology of neuronal growth cones and the distal axon by regulating actin dynamics through the guanine nucleotide exchange factor-Rho GTPase signaling pathway. | Non-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factors.
Shin EY, Lee CS, Yun CY, Won SY, Kim HK, Lee YH, Kwak SJ, Kim EG., Free PMC Article | 01/24/2015 |
| FHL1 exists as part of a complex, which binds gamma-actin and non-muscle myosin IIB | Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.
Wang L, Miao J, Li L, Wu D, Zhang Y, Peng Z, Zhang L, Yuan Z, Sun K., Free PMC Article | 09/6/2014 |
| NM II manages several major processes involved in the beta cell response to glucose, including gamma-actin protrusion and remodelling, FA assembly and turnover, and the secretory granule approach to the basal membrane | Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion.
Arous C, Rondas D, Halban PA. | 10/19/2013 |
| IIb MHC transcriptional regulation during muscle maturation to the adult state is consistent with the previously defined model of antisense-mediated coordination of genomically adjacent MHC genes, as is evident in the transcriptionally divergent euthyroid and hypothyroid states. | Regulation of an antisense RNA with the transition of neonatal to IIb myosin heavy chain during postnatal development and hypothyroidism in rat skeletal muscle.
Pandorf CE, Jiang W, Qin AX, Bodell PW, Baldwin KM, Haddad F., Free PMC Article | 11/24/2012 |
| These data support the idea that Myosin II motor-force generation is a general mechanism that supports memory consolidation in the mammalian CNS. | Myosin II motor activity in the lateral amygdala is required for fear memory consolidation.
Gavin CF, Rubio MD, Young E, Miller C, Rumbaugh G., Free PMC Article | 04/14/2012 |
| visual stimulation may play a role in the signals that regulate both nmMyH IIB and EO-MyHC developmental transitions | Postnatal changes in the developing rat extraocular muscles.
Moncman CL, Andrade ME, Andrade FH., Free PMC Article | 08/20/2011 |
| myosin IIb motor activity is downstream of LTP induction and is necessary for the emergence of actin structures that stabilize an early phase of LTP, and myosin IIb activity contributes to an actin-dependent process that underlies memory consolidation | Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation.
Rex CS, Gavin CF, Rubio MD, Kramar EA, Chen LY, Jia Y, Huganir RL, Muzyczka N, Gall CM, Miller CA, Lynch G, Rumbaugh G., Free PMC Article | 10/4/2010 |
| These results provide important insights related to how proximal IIb MHC promoter elements regulate the increased expression of the IIb MHC gene in response to inactivity of a predominantly slow postural muscle. | Transcriptional regulation of the myosin heavy chain IIb gene in inactive rat soleus.
McCall GE, Haddad F, Roy RR, Zhong H, Edgerton VR, Baldwin KM., Free PMC Article | 01/21/2010 |
| Isolated Myh10 from rat skeletal muscle and report amino sequence. | Mass spectrometry analyses of rat 2b myosin heavy chain isoform.
Zurmanová J, Maláčová D, Půta F, Novák P, Rícný J, Soukup T. | 01/21/2010 |
| non-muscle myosin II and myosin light chain kinase are downstream targets for vasopressin signaling in the renal collecting duct | Non-muscle myosin II and myosin light chain kinase are downstream targets for vasopressin signaling in the renal collecting duct.
Chou CL, Christensen BM, Frische S, Vorum H, Desai RA, Hoffert JD, de Lanerolle P, Nielsen S, Knepper MA. | 01/21/2010 |
| the SMB isoform is the predominant form expressed in rat veins, providing one possible mechanism for the faster response of veins to vasoconstrictors | Preferential myosin heavy chain isoform B Expression may contribute to the faster velocity of contraction in veins versus arteries.
Rondelli CM, Szasz IT, Kayal A, Thakali K, Watson RE, Rovner AS, Eddinger TJ, Fink GD, Watts SW. | 01/21/2010 |
| These results suggest that the mesangial expression of SMemb is related to glomerular matrix accumulation and that angiotensin II mediates both mesangial processes via AT1 receptors. | Angiotensin II enhances glomerular expression of a nonmuscle myosin heavy chain, SMemb, with extracellular matrix accumulation.
Mise N, Kimura K, Kurabayashi M, Nagai R, Okuda T, Ohba S, Suzuki N, Miyashita K, Kamijo A, Tojo A, Goto A, Omata M. | 01/21/2010 |