| The transcription regulators ZNF750 and LSD1/KDM1A dampen inflammation on the skin's surface by silencing pattern recognition receptors. | The transcription regulators ZNF750 and LSD1/KDM1A dampen inflammation on the skin's surface by silencing pattern recognition receptors.
Liu Y, Chen Y, Batzorig U, Li J, Fernández-Méndez C, Mahapatra S, Li F, Sam S, Dokoshi T, Hong SP, Nakatsuji T, Gallo RL, Sen GL., | 10/15/2024 |
| The GRHL3-regulated long non-coding RNA lnc-DC modulates keratinocytes differentiation by interacting with IGF2BP2 and up-regulating ZNF750. | The GRHL3-regulated long non-coding RNA lnc-DC modulates keratinocytes differentiation by interacting with IGF2BP2 and up-regulating ZNF750.
Hu XT, Wu XF, Sui LM, Ao LQ, Pu CX, Yuan M, Xing W, Xu X. | 04/18/2024 |
| ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer. | ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer.
Montanaro M, Agostini M, Anemona L, Bonanno E, Servadei F, Finazzi Agrò E, Asimakopoulos AD, Ganini C, Cipriani C, Signoretti M, Bove P, Rugolo F, Imperiali B, Melino G, Mauriello A, Scimeca M., Free PMC Article | 04/17/2023 |
| ZNF750 facilitates carcinogenesis via promoting the expression of long non-coding RNA CYTOR and influences pharmacotherapy response in colon adenocarcinoma. | ZNF750 facilitates carcinogenesis via promoting the expression of long non-coding RNA CYTOR and influences pharmacotherapy response in colon adenocarcinoma.
Xia L, Lin H, Zhou Y, Lian J., Free PMC Article | 07/23/2022 |
| Biased expression of mutant alleles in cancer-related genes in esophageal squamous cell carcinoma. | Biased expression of mutant alleles in cancer-related genes in esophageal squamous cell carcinoma.
Takahashi M, Hosomichi K, Nakaoka H, Sakata H, Uesato N, Murakami K, Kano M, Toyozumi T, Matsumoto Y, Isozaki T, Sekino N, Otsuka R, Inoue I, Matsubara H. | 04/2/2022 |
| PAX6 upstream antisense RNA (PAUPAR) inhibits colorectal cancer progression through modulation of the microRNA (miR)-17-5p / zinc finger protein 750 (ZNF750) axis. | PAX6 upstream antisense RNA (PAUPAR) inhibits colorectal cancer progression through modulation of the microRNA (miR)-17-5p / zinc finger protein 750 (ZNF750) axis.
Wen R, Chen C, Zhong X, Hu C., Free PMC Article | 12/18/2021 |
| Resveratrol suppresses malignant progression of oral squamous cell carcinoma cells by inducing the ZNF750/RAC1 signaling pathway. | Resveratrol suppresses malignant progression of oral squamous cell carcinoma cells by inducing the ZNF750/RAC1 signaling pathway.
Xiao Y, Duan Y, Wang Y, Yin X., Free PMC Article | 12/4/2021 |
| Identification of calmodulin-like protein 5 as tumor-suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix. | Identification of calmodulin-like protein 5 as tumor-suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix.
Kitazawa S, Takaoka Y, Ueda Y, Kitazawa R. | 09/18/2021 |
| Zinc finger protein 750(ZNF750), negatively regulated by miR-17-5p, inhibits proliferation, motility and invasion of colonic cancer cells. | Zinc finger protein 750(ZNF750), negatively regulated by miR-17-5p, inhibits proliferation, motility and invasion of colonic cancer cells.
Qu J, Zhang X, Lv X. | 08/7/2021 |
| ZNF750 inhibits the proliferation and invasion of melanoma cells through modulating the Wnt/b-catenin signaling pathway. | ZNF750 inhibits the proliferation and invasion of melanoma cells through modulating the Wnt/b-catenin signaling pathway.
Du Y, Lv G, Jing C, Liu J, Liu J. | 07/24/2021 |
| Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC. | Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.
Kong P, Xu E, Bi Y, Xu X, Liu X, Song B, Zhang L, Cheng C, Yan T, Qian Y, Yang J, Ma Y, Cui H, Zhai Y, Zou B, Liu X, Cheng Y, Guo S, Cheng X, Cui Y., Free PMC Article | 04/17/2021 |
| ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes. | ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes.
Cassandri M, Butera A, Amelio I, Lena AM, Montanaro M, Mauriello A, Anemona L, Candi E, Knight RA, Agostini M, Melino G. | 12/5/2020 |
| Study revealed that ZNF750 is both necessary and sufficient for HOPX induction and propose that HOPX functions as a positive regulator of epidermal late differentiation within a p63-ZNF750-HOPX pathway to up-regulate the key proteins required for terminal epidermal differentiation, providing clarity to previous studies showing conflicting results. | HOPX Is a ZNF750 Target that Promotes Late Epidermal Differentiation.
Chen SY, Ishii MA, Cheng B, Otten ABC, Sun BK., Free PMC Article | 06/20/2020 |
| Loss of ZNF750 expression is seen even in tumors without truncating mutations and reduced in many of the remaining ocular and cutaneous Sebaceous carcinoma. In contrast, no ZNF750 loss was detected in benign sebaceous proliferations | Loss of ZNF750 in ocular and cutaneous sebaceous carcinoma.
North JP, Solomon DA, Golovato J, Bloomer M, Benz SC, Cho RJ., Free PMC Article | 02/8/2020 |
| the cell cycle pathway was a key factor involved in the anti-tumor effect of ZNF750 in CAL-27 cells. | RNA sequencing analysis of the CAL-27 cell response to over-expressed ZNF750 gene revealed an extensive regulation on cell cycle.
Liu X, Yang Y, Xu C, Yang H, Chen S, Chen H. | 02/8/2020 |
| The findings uncovered the critical role of N(6)-methyladenosine in nasopharyngeal carcinoma (NPC), and stressed the regulatory function of the ZNF750-FGF14 signaling axis in modulating NPC progression, which provides theoretical guidance for the clinical treatment of NPC. | m(6)A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression.
Zhang P, He Q, Lei Y, Li Y, Wen X, Hong M, Zhang J, Ren X, Wang Y, Yang X, He Q, Ma J, Liu N., Free PMC Article | 11/30/2019 |
| ZNF750 acts as a potential tumor suppressor gene, and regulates tumor microenvironment. | ZNF750 inhibited the malignant progression of oral squamous cell carcinoma by regulating tumor vascular microenvironment.
Pan L, Yang H, Xu C, Chen S, Meng Z, Li K, Chen H. | 11/17/2018 |
| The low expression of ZNF750 was significantly associated with a poor prognosis. | ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma.
Otsuka R, Akutsu Y, Sakata H, Hanari N, Murakami K, Kano M, Toyozumi T, Takahashi M, Matsumoto Y, Sekino N, Yokoyama M, Okada K, Shiraishi T, Komatsu A, Iida K, Matsubara H., Free PMC Article | 03/3/2018 |
| ZNF750 expression predicts sensitivity to CRT and can be a biomarker that reliably predicts the response of ESCC to CRT. | ZNF750 Expression as a Novel Candidate Biomarker of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma.
Otsuka R, Akutsu Y, Sakata H, Hanari N, Murakami K, Kano M, Takahashi M, Matsumoto Y, Sekino N, Yokoyama M, Iida K, Matsubara H. | 12/16/2017 |
| ZNF750 Mutation is associated with esophageal squamous cell carcinoma. | Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.
Hao JJ, Lin DC, Dinh HQ, Mayakonda A, Jiang YY, Chang C, Jiang Y, Lu CC, Shi ZZ, Xu X, Zhang Y, Cai Y, Wang JW, Zhan QM, Wei WQ, Berman BP, Wang MR, Koeffler HP., Free PMC Article | 09/9/2017 |
| Suggest no connection of ZNF750 variants with psoriasis or its subphenotypes. | Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.
Dębniak T, Soczawa E, Boer M, Różewicka-Czabańska M, Wiśniewska J, Serrano-Fernandez P, Mirecka A, Paszkowska-Szczur K, Lubinski J, Krysztoforska L, Adamski Z, Maleszka R., Free PMC Article | 11/22/2014 |
| ZNF750 thus controls differentiation in concert with RCOR1 and CTBP1/2 by acting with either KDM1A to repress progenitor genes or KLF4 to induce differentiation genes. | ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.
Boxer LD, Barajas B, Tao S, Zhang J, Khavari PA., Free PMC Article | 11/8/2014 |
| ZNF750 was specifically expressed in the epidermal suprabasal layers and its expression was augmented during differentiation, both in human skin and in-vitro, peaking in the granular layer. | ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes.
Cohen I, Birnbaum RY, Leibson K, Taube R, Sivan S, Birk OS., Free PMC Article | 04/27/2013 |
| ZNF750 directly links a tissue-specifying factor, p63, to an effector of terminal differentiation, KLF4. | ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.
Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA., Free PMC Article | 05/19/2012 |
| Two haplotypes of ZNF750 and rare 5' regulatory variants of ZNF750 were found to be associated with psoriasis. | Association analysis identifies ZNF750 regulatory variants in psoriasis.
Birnbaum RY, Hayashi G, Cohen I, Poon A, Chen H, Lam ET, Kwok PY, Birk OS, Liao W., Free PMC Article | 03/24/2012 |