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    MAP9 microtubule associated protein 9 [ Homo sapiens (human) ]

    Gene ID: 79884, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement.

    MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement.
    Tran MV, Khuntsariya D, Fetter RD, Ferguson JW, Wang JT, Long AF, Cote LE, Wellard SR, Vázquez-Martínez N, Sallee MD, Genova M, Magiera MM, Eskinazi S, Lee JD, Peel N, Janke C, Stearns T, Shen K, Lansky Z, Magescas J, Feldman JL.,

    02/5/2024
    Expression of MAP9 in Epstein-Barr virus-associated gastric carcinoma.

    Expression of MAP9 in Epstein-Barr virus-associated gastric carcinoma.
    Xiao H, Sun J, Huang W, Liu W, Zhang Y, Wang H, Luo B.

    03/12/2022
    MAP9/ERCC3 signaling cascade: A new insight on understanding the chromosomal instability in hepatocellular carcinoma.

    MAP9/ERCC3 signaling cascade: A new insight on understanding the chromosomal instability in hepatocellular carcinoma.
    Mok EHK, Leung CON, Lee TKW., Free PMC Article

    03/13/2021
    MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.

    MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
    Wang S, Huang J, Li C, Zhao L, Wong CC, Zhai J, Zhou Y, Deng W, Zeng Y, Gao S, Zhang Y, Wang G, Guan XY, Wei H, Wong SH, He HH, Shay JW, Yu J.

    12/19/2020
    Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3.

    Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3.
    Zhang J, Huang JZ, Zhang YQ, Zhang X, Zhao LY, Li CG, Zhou YF, Wei H, Yu J., Free PMC Article

    12/19/2020
    Data suggest miR-320a/microtubule-associated protein 9 (MAP9) as promising targets for the treatment and prevention of postmenopausal osteoporosis (PMO).

    MiR-320a was highly expressed in postmenopausal osteoporosis and acts as a negative regulator in MC3T3E1 cells by reducing MAP9 and inhibiting PI3K/AKT signaling pathway.
    Kong Y, Nie ZK, Li F, Guo HM, Yang XL, Ding SF.

    02/29/2020
    MAP9 rs1058992 polymorphism is associated with risk of EBV-associated gastric carcinoma

    MAP9 single nucleotide polymorphism rs1058992 is a risk of EBV-associated gastric carcinoma in Chinese population.
    Liu W, Xiao H, Wu S, Liu H, Luo B.

    05/25/2019
    MAP9 downregulation is associated with colorectal malignancy.

    Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers.
    Rouquier S, Pillaire MJ, Cazaux C, Giorgi D., Free PMC Article

    01/24/2015
    ASAP stabilizes p53 both by alleviating MDM2-mediated p53 ubiquitination and by enhancing its p300-dependent acetylation.

    Induction of ASAP (MAP9) contributes to p53 stabilization in response to DNA damage.
    Basbous J, Knani D, Bonneaud N, Giorgi D, Brondello JM, Rouquier S.

    10/20/2012
    Results highlight dual ASAP regulation by Plk1 and further confirm the importance of ASAP for spindle pole organization, bipolar spindle assembly, and mitosis.

    Plk1 regulates both ASAP localization and its role in spindle pole integrity.
    Eot-Houllier G, Venoux M, Vidal-Eychenié S, Hoang MT, Giorgi D, Rouquier S., Free PMC Article

    10/4/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Study demonstrates that AurA-mediated phosphorylation of ASAP is essential to spindle formation and mitosis.

    ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.
    Venoux M, Basbous J, Berthenet C, Prigent C, Fernandez A, Lamb NJ, Rouquier S.

    01/21/2010
    ASAP is a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis.

    ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis.
    Saffin JM, Venoux M, Prigent C, Espeut J, Poulat F, Giorgi D, Abrieu A, Rouquier S., Free PMC Article

    01/21/2010
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