[Progress on the involvement of HDAC11 in the regulation of mammalian oocyte maturation and early embryonic development]. | [Progress on the involvement of HDAC11 in the regulation of mammalian oocyte maturation and early embryonic development]. Shi JQ, Liu XF, Wang C. | 07/10/2024 |
HDAC11 Regulates Palmitate-induced NLRP3 Inflammasome Activation by Inducing YAP Expression in THP-1 Cells and PBMCs. | HDAC11 Regulates Palmitate-induced NLRP3 Inflammasome Activation by Inducing YAP Expression in THP-1 Cells and PBMCs. Byeon HE, Choi SE, Kim Y, Choi S, Lee SJ, Kim DH, Mo JS, Jeon JY. | 03/1/2024 |
HDAC11: A novel target for improved cancer therapy. | HDAC11: A novel target for improved cancer therapy. Liu Y, Tong X, Hu W, Chen D. | 09/22/2023 |
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma. | HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma. Sriramareddy SN, Faião-Flores F, Emmons MF, Saha B, Chellappan S, Wyatt C, Smalley I, Licht JD, Durante MA, Harbour JW, Smalley KSM., Free PMC Article | 12/24/2022 |
HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3. | HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT3. Wu H, Yin X, Zhao X, Wu Z, Xiao Y, Di Q, Sun P, Tang H, Quan J, Chen W., Free PMC Article | 10/8/2022 |
A pan-cancer analysis identifies HDAC11 as an immunological and prognostic biomarker. | A pan-cancer analysis identifies HDAC11 as an immunological and prognostic biomarker. Li R, Wu X, Zhao P, Xue K, Li J. | 06/11/2022 |
HDAC11: a multifaceted histone deacetylase with proficient fatty deacylase activity and its roles in physiological processes. | HDAC11: a multifaceted histone deacetylase with proficient fatty deacylase activity and its roles in physiological processes. Núñez-Álvarez Y, Suelves M. | 05/28/2022 |
HDAC11 Regulates Glycolysis through the LKB1/AMPK Signaling Pathway to Maintain Hepatocellular Carcinoma Stemness. | HDAC11 Regulates Glycolysis through the LKB1/AMPK Signaling Pathway to Maintain Hepatocellular Carcinoma Stemness. Bi L, Ren Y, Feng M, Meng P, Wang Q, Chen W, Jiao Q, Wang Y, Du L, Zhou F, Jiang Y, Chen F, Wang C, Tang B, Wang Y. | 09/18/2021 |
Long noncoding RNA BCYRN1 promotes prostate cancer progression via elevation of HDAC11. | Long non‑coding RNA BCYRN1 promotes prostate cancer progression via elevation of HDAC11. Huo W, Qi F, Wang K. | 05/22/2021 |
Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2. | Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2. Bora-Singhal N, Mohankumar D, Saha B, Colin CM, Lee JY, Martin MW, Zheng X, Coppola D, Chellappan S., Free PMC Article | 12/5/2020 |
HDAC11 is a regulatory molecule in Th2 response and plays a critical role in the restriction of the biased IL-13 expression in CD4(+) T cells of the heart. | HDAC11 regulates interleukin-13 expression in CD4+ T cells in the heart. Yuan L, Chen X, Cheng L, Rao M, Chen K, Zhang N, Meng J, Li M, Yang LT, Yang PC, Wang X, Song J. | 12/14/2019 |
IL-10 expression was compromised in the peripheral B cells of allergic rhinitis (AR) patients. Inhibition of HDAC11 restored the IL-10 expression ability in the AR-B cells. We also found a negative correlation between HDAC11 and the expression of IL-10 in B cells; this fact indicates that HDAC11 interferes with the expression of IL-10 in B cells. | Histone deacetylase 11 inhibits interleukin 10 in B cells of subjects with allergic rhinitis. Shao JB, Luo XQ, Wu YJ, Li MG, Hong JY, Mo LH, Liu ZG, Li HB, Liu DB, Yang PC. | 08/10/2019 |
regulates type I interferon signaling through defatty-acylation of SHMT2 | HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2. Cao J, Sun L, Aramsangtienchai P, Spiegelman NA, Zhang X, Huang W, Seto E, Lin H., Free PMC Article | 06/1/2019 |
report in vitro profiling of HDAC11 deacylase activities | Histone Deacetylase 11 Is a Fatty-Acid Deacylase. Kutil Z, Novakova Z, Meleshin M, Mikesova J, Schutkowski M, Barinka C. | 04/6/2019 |
The results indicated that HDAC11 was significantly expressed in human and mouse diabetic heart failure (DHF) hearts. | HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury. Fan XD, Wan LL, Duan M, Lu S. | 12/22/2018 |
Mycobacterium tuberculosis infection disturbs the HDAC6/HDAC11 levels to induce IL-10 expression in macrophages. | Mycobacterium tuberculosis infection induces IL-10 gene expression by disturbing histone deacetylase 6 and histonedeacetylase 11 equilibrium in macrophages. Wang X, Wu Y, Jiao J, Huang Q. | 11/24/2018 |
HDAC11 was initially identified as a negative regulator of the well-known anti-inflammatory cytokine IL-10. Hence, antagonizing HDAC11 activity may have anti-tumor potential, whereas activating HDAC11 may be useful to treat chronic inflammation or autoimmunity. | HDAC11 is a regulator of diverse immune functions. Yanginlar C, Logie C. | 04/14/2018 |
Results showed that the high levels of HDAC11 and lower levels of p53 were detected in pituitary tumor cells. A negative correlation was detected between the data of HDAC11 and p53. | Histone deacetylase 11 suppresses p53 expression in pituitary tumor cells. Wang W, Fu L, Li S, Xu Z, Li X. | 04/14/2018 |
Our study identified a group of cell cycle-promoting genes regulated by HDAC11. | Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. Thole TM, Lodrini M, Fabian J, Wuenschel J, Pfeil S, Hielscher T, Kopp-Schneider A, Heinicke U, Fulda S, Witt O, Eggert A, Fischer M, Deubzer HE., Free PMC Article | 11/18/2017 |
High HDAC11 expression is associated with neoplasms. | HDAC11 is a novel drug target in carcinomas. Deubzer HE, Schier MC, Oehme I, Lodrini M, Haendler B, Sommer A, Witt O. | 05/11/2013 |
Data indicate a pronounced deregulation of HDAC genes HDAC9 and HDAC11 in patients with Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF). | Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms. Skov V, Larsen TS, Thomassen M, Riley CH, Jensen MK, Bjerrum OW, Kruse TA, Hasselbalch HC. | 06/23/2012 |
These results demonstrate for the first time that HDAC11 plays an essential role in regulating OX40L expression. | HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma. Buglio D, Khaskhely NM, Voo KS, Martinez-Valdez H, Liu YJ, Younes A., Free PMC Article | 05/21/2011 |
HDAC11 associates with replication origins inhibits Cdt1-induced re-replication and suppresses MCM loading. | Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin. Wong PG, Glozak MA, Cao TV, Vaziri C, Seto E, Alexandrow M., Free PMC Article | 02/26/2011 |
We found a reduction of HDAC 11 mRNA and increased HDAC 2 levels in amyotrophic lateral sclerosis brain and spinal cord compared with controls. | Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis. Janssen C, Schmalbach S, Boeselt S, Sarlette A, Dengler R, Petri S. | 06/28/2010 |
Cdt1 undergoes acetylation and is reversibly deacetylated by HDAC11 | Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1. Glozak MA, Seto E., Free PMC Article | 01/21/2010 |