| TSGA10 as a Potential Key Factor in the Process of Spermatid Differentiation/Maturation: Deciphering Its Association with Autophagy Pathway. | TSGA10 as a Potential Key Factor in the Process of Spermatid Differentiation/Maturation: Deciphering Its Association with Autophagy Pathway.
Asgari R, Bakhtiari M, Rezazadeh D, Yarani R, Esmaeili F, Mansouri K. | 03/5/2022 |
| Pathogenesis of acephalic spermatozoa syndrome caused by splicing mutation and de novo deletion in TSGA10. | Pathogenesis of acephalic spermatozoa syndrome caused by splicing mutation and de novo deletion in TSGA10.
Xiang M, Wang Y, Xu W, Zheng N, Zhang J, Duan Z, Zha X, Shi X, Wang F, Cao Y, Zhu F., Free PMC Article | 02/26/2022 |
| Novel mutations in PMFBP1, TSGA10 and SUN5: Expanding the spectrum of mutations that may cause acephalic spermatozoa. | Novel mutations in PMFBP1, TSGA10 and SUN5: Expanding the spectrum of mutations that may cause acephalic spermatozoa.
Liu G, Wang N, Zhang H, Yin S, Dai H, Lin G, Li W. | 06/5/2021 |
| Hypoxia-induced microRNA-10b-3p promotes esophageal squamous cell carcinoma growth and metastasis by targeting TSGA10. | Hypoxia-induced microRNA-10b-3p promotes esophageal squamous cell carcinoma growth and metastasis by targeting TSGA10.
Zhang Q, Zhang J, Fu Z, Dong L, Tang Y, Xu C, Wang H, Zhang T, Wu Y, Dong C, Shao S, Wang G., Free PMC Article | 10/3/2020 |
| Overexpression of TSGA10, as a tumor suppressor gene, in endothelial cells resulted in decreased proliferation, migration and therefore, angiogenic activity of HUVECs and may involved HIF2a binding. | TSGA10 overexpression inhibits angiogenesis of HUVECs: A HIF-2α biased perspective.
Amoorahim M, Valipour E, Hoseinkhani Z, Mahnam A, Rezazadeh D, Ansari M, Shahlaei M, Gamizgy YH, Moradi S, Mansouri K. | 08/1/2020 |
| TSGA10 overexpression could decrease the metastatic and metabolic activity of cancer cells through its inhibitory effect on HIF-1 activity. Therefore, TSGA10 could be considered in the research for therapeutic candidates in cancer. | TSGA10 Over Expression Decreases Metastasic and Metabolic Activity by Inhibiting HIF-1 in Breast Cancer Cells.
Jahani M, Shahlaei M, Norooznezhad F, Miraghaee SS, Hosseinzadeh L, Moasefi N, Khodarahmi R, Farokhi A, Mahnam A, Mansouri K. | 08/1/2020 |
| we speculate that the presence of rare sequence variants within TSGA10 may be associated with acephalic spermatozoa in humans | TSGA10 is a novel candidate gene associated with acephalic spermatozoa.
Sha YW, Sha YK, Ji ZY, Mei LB, Ding L, Zhang Q, Qiu PP, Lin SB, Wang X, Li P, Xu X, Li L. | 10/5/2019 |
| This study showed the role of Lactobacilli in down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes. Such expression change might be involved in the anticancer effects of these Lactobacilli. The underlying mechanisms of these observations are not clear but epigenetic modulatory mechanisms may participate in this process. | Down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes by Lactobacillus rhamnosus GG and Lactobacillus crispatus SJ-3C-US supernatants in HeLa cell line.
Nouri Z, Neyazi N, Modarressi, Karami F, Abedin-Do A, Taherian-Esfahani Z, Ghafouri-Fard S, Motevaseli E. | 09/7/2019 |
| the current study showed that TSGA10 could be considered as a tumor suppressor in acute myeloid leukemia | Contribution and prognostic value of TSGA10 gene expression in patients with acute myeloid leukemia (AML).
Hoseinkhani Z, Rastegari-Pouyani M, Oubari F, Mozafari H, Rahimzadeh AB, Maleki A, Amini S, Mansouri K. | 04/13/2019 |
| Results show that TSGA10 is directly regulated by mir-23a which targeted the 3'UTR of mir-23a to regulate angiogenesis. | Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10.
Bao L, You B, Shi S, Shan Y, Zhang Q, Yue H, Zhang J, Zhang W, Shi Y, Liu Y, Wang X, Liu D, You Y., Free PMC Article | 03/2/2019 |
| TSGA10 tends to express variants with shorter 5'UTR. | Identification of new TSGA10 transcript variants in human testis with conserved regulatory RNA elements in 5'untranslated region and distinct expression in breast cancer.
Salehipour P, Nematzadeh M, Mobasheri MB, Afsharpad M, Mansouri K, Modarressi MH. | 11/4/2017 |
| Overexpression of TSGA10 would induce disruption of HIF-1alpha axis and exert potent inhibitory effects on tumor angiogenesis and metastasis. | New function of TSGA10 gene in angiogenesis and tumor metastasis: a response to a challengeable paradox.
Mansouri K, Mostafie A, Rezazadeh D, Shahlaei M, Modarressi MH. | 10/22/2016 |
| Report role for mir-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression. | Effects and interactions of MiR-577 and TSGA10 in regulating esophageal squamous cell carcinoma.
Yuan X, He J, Sun F, Gu J., Free PMC Article | 08/9/2014 |
| TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients | TSGA10 - A target for autoantibodies in autoimmune polyendocrine syndrome type 1 and systemic lupus erythematosus.
Smith CJ, Oscarson M, Rönnblom L, Alimohammadi M, Perheentupa J, Husebye ES, Gustafsson J, Nordmark G, Meloni A, Crock PA, Kämpe O, Bensing S. | 02/5/2011 |
| TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin | Filament-associated TSGA10 protein is expressed in professional antigen presenting cells and interacts with vimentin.
Roghanian A, Jones DC, Pattisapu JV, Wolfe J, Young NT, Behnam B. | 11/27/2010 |
| TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1). | Testis-expressed protein TSGA10 an auto-antigen in autoimmune polyendocrine syndrome type I.
Reimand K, Perheentupa J, Link M, Krohn K, Peterson P, Uibo R. | 01/21/2010 |
| The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia. | Expression of the testis-specific gene, TSGA10, in Iranian patients with acute lymphoblastic leukemia (ALL).
Mobasheri MB, Modarressi MH, Shabani M, Asgarian H, Sharifian RA, Vossough P, Shokri F. | 01/21/2010 |
| over-expressed in 4 of 20 hepatocellular carcinomas (HCC), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers | Over-expression of the testis-specific gene TSGA10 in cancers and its immunogenicity.
Tanaka R, Ono T, Sato S, Nakada T, Koizumi F, Hasegawa K, Nakagawa K, Okumura H, Yamashita T, Ohtsuka M, Asagoe K, Yamasaki O, Noguchi Y, Iwatsuki K, Nakayama E. | 01/21/2010 |