| Upregulation of Megalin, Cubilin, NGAL mRNA expression in kidney may represent tubular injury and apoptosis in chronic condition of rat diabetic model. | Upregulation of Megalin, Cubilin, NGAL mRNA expression in kidney may represent tubular injury and apoptosis in chronic condition of rat diabetic model.
Romi MM, Anggorowati N, Maulida DS, Suskalanggeng MWAH, Setyaningsih WAW, Sari DCR, Arfian N. | 10/23/2021 |
| The inhibition of megalin/cubilin or lysosomal cathepsin B reduced albuminuria-induced NLRP3 inflammasome activation. | Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation.
Liu D, Wen Y, Tang TT, Lv LL, Tang RN, Liu H, Ma KL, Crowley SD, Liu BC., Free PMC Article | 10/17/2015 |
| We conclude that the megalin/cubilin/amnionless/Dab2 complex/es participate in intestinal processes, mainly during the lactation period and that Dab2 may act as an adaptor in intestinal processes mediated by ApoER2 and VLDLR. | Dab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling rat.
Vázquez-Carretero MD, Palomo M, García-Miranda P, Sánchez-Aguayo I, Peral MJ, Calonge ML, Ilundain AA. | 10/25/2014 |
| used immunocytochemistry and reverse transcription-polymerase chain reaction on laser-captured glomeruli to demonstrate synthesis and expression of cubilin in glomerular podocytes | Cubilin is expressed in rat and human glomerular podocytes.
Prabakaran T, Christensen EI, Nielsen R, Verroust PJ. | 01/12/2013 |
| cubilin and megalin constitute a dual-receptor complex facilitating the function of each other in the inner ear | Cubilin and megalin co-localize in the neonatal inner ear.
Tauris J, Christensen EI, Nykjaer A, Jacobsen C, Petersen CM, Ovesen T. | 01/21/2010 |
| Three distinct regions of cubilin bind to megalin and its interactions with both megalin and amnionless are essential for its intracellular stability. | Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability.
Ahuja R, Yammani R, Bauer JA, Kalra S, Seetharam S, Seetharam B. | 01/21/2010 |
| Significant amounts of megalin and cubilin were present in the glomerular cells in addition to the proximal tubular cells. The quantity of these receptors progressively increased in the glomerulus with age. | Age-related change of endocytic receptors megalin and cubilin in the kidney in rats.
Odera K, Goto S, Takahashi R. | 01/21/2010 |
| AMN interacts with the EGF domains of cubilin for membrane attachment and export from the endoplasmic reticulum, while extracellular cubilin does apical sorting of the complex in a carbohydrate-dependent manner | Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex.
Coudroy G, Gburek J, Kozyraki R, Madsen M, Trugnan G, Moestrup SK, Verroust PJ, Maurice M. | 01/21/2010 |
| These data suggest that light chains bind the tandem megalin-cubilin complex. | Light chains are a ligand for megalin.
Klassen RB, Allen PL, Batuman V, Crenshaw K, Hammond TG. | 01/21/2010 |
| endocytic receptors megalin and cubilin are involved in renal reabsorption of myoglobin | Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin.
Gburek J, Birn H, Verroust PJ, Goj B, Jacobsen C, Moestrup SK, Willnow TE, Christensen EI. | 01/21/2010 |
| Cubilin expression at later developmental stages of the rodent embryo and its correlation to that of megalin was investigated. | Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo.
Assémat E, Châtelet F, Chandellier J, Commo F, Cases O, Verroust P, Kozyraki R. | 01/21/2010 |
| We provide the first evidence of the regulation of a Cbl-specific receptor by the vitamin itself in some rat organs. | Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs.
Kalra S, Ahuja R, Mutti E, Veber D, Seetharam S, Scalabrino G, Seetharam B. | 01/21/2010 |