| FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7. | FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7.
Li J, Tian J, Ma M, Qin Z, Cao B, Yang J, Wang X, Yang X. | 11/6/2024 |
| METTL3 regulates FAM83D m[6]A modification to accelerate tumorigenesis of triple-negative breast cancer via the Wnt/beta-catenin pathway. | METTL3 regulates FAM83D m(6)A modification to accelerate tumorigenesis of triple-negative breast cancer via the Wnt/β-catenin pathway.
Yu X, Li Y, Kong F, Xu Q. | 01/16/2024 |
| Systematic analysis of the oncogenic role of FAM83D across cancers based on data mining. | Systematic analysis of the oncogenic role of FAM83D across cancers based on data mining.
Geng Y, Liu J, Wang Z, Liu T, Peng X, Huang Y., Free PMC Article | 03/29/2023 |
| miRNA-142-3p functions as a potential tumor suppressor directly targeting FAM83D in the development of ovarian cancer. | miRNA-142-3p functions as a potential tumor suppressor directly targeting FAM83D in the development of ovarian cancer.
Gao G, Guo X, Gu W, Lu Y, Chen Z., Free PMC Article | 05/14/2022 |
| Immune implication of FAM83D gene in hepatocellular carcinoma. | Immune implication of FAM83D gene in hepatocellular carcinoma.
Meng T, Tong Z, Yang MY, Zhang Y, Liu Y, Wang ZZ, Zhu LX, Wu J., Free PMC Article | 12/18/2021 |
| Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy. | Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS. | 08/14/2021 |
| FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer. | FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer.
Yin C, Lin X, Wang Y, Liu X, Xiao Y, Liu J, Snijders AM, Wei G, Mao JH, Zhang P. | 01/2/2021 |
| circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D. | circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W., Free PMC Article | 12/12/2020 |
| FAM83D promotes ovarian cancer progression and its potential application in diagnosis of invasive ovarian cancer. | FAM83D promotes ovarian cancer progression and its potential application in diagnosis of invasive ovarian cancer.
Zhang Q, Yu S, Lok SIS, Wong AST, Jiao Y, Lee LTO., Free PMC Article | 08/13/2020 |
| Overexpressed in tumors, family with sequence similarity 83 member D protein FAM83D (FAM83D) is associated with gender, AJCC stage, tumor recurrence and survival in hepatocellular carcinoma (HCC). | FAM83D is associated with gender, AJCC stage, overall survival and disease-free survival in hepatocellular carcinoma.
Liu X, Gao H, Zhang J, Xue D., Free PMC Article | 07/11/2020 |
| FAM83D promotes HCC recurrence by promoting CD44 expression and CD44+ CSCs malignancy. | FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells.
Lin B, Chen T, Zhang Q, Lu X, Zheng Z, Ding J, Liu J, Yang Z, Geng L, Wu L, Zhou L, Zheng S., Free PMC Article | 03/3/2018 |
| FAM83D knockdown up-regulated the protein expression level of F-box and WD repeat domain-containing 7 (FBXW7), but diminished the Notch1 protein expression level. | FAM83D knockdown regulates proliferation, migration and invasion of colorectal cancer through inhibiting FBXW7/Notch-1 signalling pathway.
Mu Y, Zou H, Chen B, Fan Y, Luo S. | 02/24/2018 |
| Higher level of FAM83D expression is positively correlated with an increase in genome instability in many cancer. | Prognostic significance of FAM83D gene expression across human cancer types.
Walian PJ, Hang B, Mao JH., Free PMC Article | 12/17/2016 |
| upregulation of FAM83D, a potential oncotarget gene, may be triggered by epigenetic events and can contribute to hepatocarcinogenesis | Upregulation of FAM83D affects the proliferation and invasion of hepatocellular carcinoma.
Liao W, Liu W, Liu X, Yuan Q, Ou Y, Qi Y, Huang W, Wang Y, Huang J., Free PMC Article | 08/13/2016 |
| NMR-derived secondary chemical shifts and relaxation properties show that the Chica LC8 binding domain is essentially disordered with a dynamically restricted segment in one linker between motifs. | The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex.
Clark S, Nyarko A, Löhr F, Karplus PA, Barbar E., Free PMC Article | 05/14/2016 |
| Taken together, these results demonstrate that FAM83D is a novel oncogene in HCC development and may constitute a potential therapeutic target in HCC. | FAM83D activates the MEK/ERK signaling pathway and promotes cell proliferation in hepatocellular carcinoma.
Wang D, Han S, Peng R, Wang X, Yang XX, Yang RJ, Jiao CY, Ding D, Ji GW, Li XC. | 05/2/2015 |
| Results demonstrate that FAM83D has prognostic value for breast cancer patients and is a novel oncogene in breast cancer development that at least in part acts through mTOR hyper-activation by inhibiting FBXW7. | FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7.
Wang Z, Liu Y, Zhang P, Zhang W, Wang W, Curr K, Wei G, Mao JH., Free PMC Article | 11/22/2014 |
| interaction partner of the chromokinesin Kid that is required for the generation of polar ejection forces and chromosome congression | The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle.
Santamaria A, Nagel S, Sillje HHW, Nigg EA. | 01/21/2010 |