that a mechanism by which Hippo pathway and F-actin synergize to modulate YAP activation and localization in the context of intervertebral disc degeneration and help to control nucleus pulposus cells proliferation | AMOT130 linking F-actin to YAP is involved in intervertebral disc degeneration. Zhang C, Wang F, Xie Z, Chen L, Sinkemani A, Yu H, Wu X., Free PMC Article | 12/22/2018 |
After 6 hours of antiorthostatic suspension alpha-actinin 1 and alpha-actinin 4 levels decreased in the membranous fraction of proteins of cardiomyocytes and soleus muscle fibers. | Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity. Ogneva IV, Biryukov NS, Leinsoo TA, Larina IM., Free PMC Article | 11/22/2014 |
Desmin and alpha-actinin-2 content in rat soleus muscle in the dynamics of gravitational unloading and subsequent reloading. | Desmin and α-actinin-2 content in rat soleus muscle in the dynamics of gravitational unloading and subsequent reloading. Mirzoev TM, Shenkman BS, Ushakov IB, Ogneva IV. | 11/17/2012 |
The alpha-actinin-1 form a complex with CLP36 and RIL. | CLP36 and RIL recruit α-actinin-1 to stress fibers and differentially regulate stress fiber dynamics in F2408 fibroblasts. Miyazaki K, Ohno K, Tamura N, Sasaki T, Sato K. | 09/15/2012 |
Data describe alterations of myocardial intercellular and cell-matrix contacts in hypertrophic tissue, and show intracellular translocation of beta-catenin, alpha-actinin and chondroitin sulfate proteoglycan 6 in both an animal model and in LVH patients. | Expression and tissue localization of beta-catenin, alpha-actinin and chondroitin sulfate proteoglycan 6 is modulated during rat and human left ventricular hypertrophy. Ridinger H, Rutenberg C, Lutz D, Buness A, Petersen I, Amann K, Maercker C. | 01/21/2010 |
Alpha-Actinin mediates the formation of the template and organization of adhesions associated with actin filaments, suggesting that actin crosslinking has a major role in this process. | Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Choi CK, Vicente-Manzanares M, Zareno J, Whitmore LA, Mogilner A, Horwitz AR., Free PMC Article | 01/21/2010 |
two sm-titin Zq domains interact with each other and with the two R2-R3 sites in the alpha-actinin central rod | Smooth muscle titin Zq domain interaction with the smooth muscle alpha-actinin central rod. Chi RJ, Simon AR, Bienkiewicz EA, Felix A, Keller TC 3rd., Free PMC Article | 01/21/2010 |
Cardiac dysfunction induced by peroxynitrite involves degradation of alpha-actinin that may be mediated by the proteolytic action of MMP-2. | Matrix metalloproteinase-2 degrades the cytoskeletal protein alpha-actinin in peroxynitrite mediated myocardial injury. Sung MM, Schulz CG, Wang W, Sawicki G, Bautista-López NL, Schulz R. | 01/21/2010 |
PINCH1, Ilk and actinin from a complex to costameres in neonatal rat ventricular myocytes. This complex is stimulated by fibronectins and phenylephrine, and by both by drug synergism, to regulate cardiac myocyte hypertrophy. | Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy. Chen H, Huang XN, Yan W, Chen K, Guo L, Tummalapali L, Dedhar S, St-Arnaud R, Wu C, Sepulveda JL. | 01/21/2010 |
an alpha-actinin-dependent association between the actin cytoskeleton and A2AR trafficking | The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. Burgueño J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F Jr, Lluis C, Franco R, Ciruela F. | 01/21/2010 |
Brain-specific splicing of alpha-actinin 1 (ACTN1) mRNA. | Brain-specific splicing of alpha-actinin 1 (ACTN1) mRNA. Kremerskothen J, Teber I, Wendholt D, Liedtke T, Böckers TM, Barnekow A. | 01/21/2010 |
the focal adhesion component alpha-actinin interacts with syndecan-4 in a beta-integrin-independent manner | Syndecan-4 associates with alpha-actinin. Greene DK, Tumova S, Couchman JR, Woods A. | 01/21/2010 |