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    Stc1 stanniocalcin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 81801, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Stanniocalcin 1 Inhibits the Inflammatory Response in Microglia and Protects Against Sepsis-Associated Encephalopathy.

    Stanniocalcin 1 Inhibits the Inflammatory Response in Microglia and Protects Against Sepsis-Associated Encephalopathy.
    Bonfante S, Joaquim L, Fileti ME, Giustina AD, de Souza Goldim MP, Danielski LG, Cittadin E, De Carli RJ, de Farias BX, Engel NA, da Rosa N, Fortunato JJ, Giridharan V, Scaini G, Rezin GT, Generoso J, de Bitencourt RM, Terra S, Barichello T, Petronilho F.

    12/11/2021
    Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity.

    Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity.
    Dalvin LA, Hartnett ME, Bretz CA, Hann CR, Cui RZ, Marmorstein AD, Sheikh-Hamad D, Fautsch MP, Roddy GW., Free PMC Article

    05/8/2021
    Results show that STC1 have an important role in the carbohydrate metabolism regulation, in particular gluconeogenesis from glutamine in the kidney, across the vertebrates.

    Stanniocalcin 1 effects on the renal gluconeogenesis pathway in rat and fish.
    Schein V, Kucharski LC, Guerreiro PM, Martins TL, Morgado I, Power DM, Canario AV, da Silva RS.

    06/4/2016
    In this study, we have found that several HIF target genes including STC1 are upregulated in AECs by a submerged condition, that STC1 is regulated by hypoxia and HIF.

    Stanniocalcin-1 is induced by hypoxia inducible factor in rat alveolar epithelial cells.
    Ito Y, Zemans R, Correll K, Yang IV, Ahmad A, Gao B, Mason RJ., Free PMC Article

    12/6/2014
    AVP-mediated elevations in STC-1 gene expression are wholly dependent on functional COX-2 activity.

    Cyclooxygenase-2 mediates induction of the renal stanniocalcin-1 gene by arginine vasopressin.
    Law AY, Hébert RL, Nasrallah R, Langenbach R, Wong CK, Wagner GF.

    05/3/2014
    Stanniocalcin-1 (STC-1) within the subfornical organ may act in a paracrine/autocrine manner to modulate the neuronal responses to blood-borne angiotensin II.

    Stanniocalcin-1 in the subfornical organ inhibits the dipsogenic response to angiotensin II.
    Moreau JM, Iqbal W, Turner JK, Wagner GF, Ciriello J.

    03/30/2013
    STC1 gene induction proceeds through cyclic AMP and ERK1/2, independently of protein kinase A, the canonical cAMP effector.

    STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons.
    Holighaus Y, Weihe E, Eiden LE., Free PMC Article

    01/26/2013
    Endogenous STC-1 signaling in nucleus solitarius is involved in regulating the excitability of neurons functioning as components of the baroreceptor reflex controlling arterial pressure.

    Effects of the calcium-regulating glycoprotein hormone stanniocalcin-1 within the nucleus of the solitary tract on arterial pressure and the baroreceptor reflex.
    Ciriello J, Oiamo TH, Moreau JM, Turner JK, Wagner GF.

    12/8/2012
    the inner medullary STC-1 gene is differentially regulated in rat and mouse by arginine vasopressin and angiotensin II

    Vasopressin controls stanniocalcin-1 gene expression in rat and mouse kidney.
    Law AY, Wong CK, Turner J, Gonzalez AA, Prieto MC, Wagner GF.

    03/10/2012
    The findings are therefore indicative of cortical and medullary STC-1 having separate roles in the renal control of extracellular fluid balance.

    The renal stanniocalcin-1 gene is differentially regulated by hypertonicity and hypovolemia in the rat.
    Turner J, Xiang FL, Feng Q, Wagner GF.

    03/5/2011
    The endogenous STC-1, similar to milk-derived STC-1, may be involved in digestion and/or absorption in gastrointestinal organs.

    Expression of stanniocalcin-1 in gastrointestinal tracts of neonatal and mature rats.
    Kobayashi R, Nakagomi Y, Shimura Y, Mochizuki M, Kobayashi K, Sugita K, Ohyama K.

    01/21/2010
    This study provides the first evidence of the regulation of STC1 expression in the male reproductive system.

    Effects of dexamethasone and dibutyryl cAMP on stanniocalcin-1 mRNA expression in rat primary Sertoli and Leydig cells.
    Li L, Wong CK.

    01/21/2010
    Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis

    Stanniocalcin 1 acts as a paracrine regulator of growth plate chondrogenesis.
    Wu S, Yoshiko Y, De Luca F.

    01/21/2010
    STC1 accelerates osteoblast development in an autocrine/paracrine manner in the rat calvaria cell culture model.

    Stanniocalcin 1 stimulates osteoblast differentiation in rat calvaria cell cultures.
    Yoshiko Y, Maeda N, Aubin JE.

    01/21/2010
    role for mammalian STC1 in modulating the immune/inflammatory response in ureteric obstruction

    Stanniocalcin-1, an inhibitor of macrophage chemotaxis and chemokinesis.
    Kanellis J, Bick R, Garcia G, Truong L, Tsao CC, Etemadmoghadam D, Poindexter B, Feng L, Johnson RJ, Sheikh-Hamad D.

    01/21/2010
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