| TGFbeta2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle. | TGFβ2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle.
Geng J, Zhang X, Zhang Y, Meng X, Sun J, Zhou B, Ma J., Free PMC Article | 09/11/2024 |
| Maternal Perinatal Exposure to Dibutyl Phthalate Promotes Ovarian Dysfunction in Adult Female Offspring via Downregulation of TGF-beta2 and TGF-beta3. | Maternal Perinatal Exposure to Dibutyl Phthalate Promotes Ovarian Dysfunction in Adult Female Offspring via Downregulation of TGF-β2 and TGF-β3.
Zhang J, Zhou K, Cheng R, Yang M, Shen X, Luo X, Xu L. | 08/13/2022 |
| beta-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs. | β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs.
Ibrahim S, Johnson M, Stephens CH, Xu J, Moore R, Mariani A, Contreras C, Syed F, Mirmira RG, Anderson RM, Sims EK., Free PMC Article | 03/26/2022 |
| Betaglycan shedding serves a major role in TGF-beta2 signaling in Sertoli cells. | Betaglycan (TβRIII) is a Key Factor in TGF-β2 Signaling in Prepubertal Rat Sertoli Cells.
Kudipudi PK, Galuska SP, Dietze R, Scheiner-Bobis G, Loveland KL, Konrad L., Free PMC Article | 04/25/2020 |
| Results show that TGF-beta2 enhanced gene expression and protein synthesis of FGF23 in osteoblast-like cells. The effect was paralleled by enhanced SOCE which was required for the full effect on Fgf23 gene expression. TGF-beta2-induced FGF23 formation presumably contributes to high plasma FGF23 levels in acute and chronic diseases. | The production of fibroblast growth factor 23 is controlled by TGF-β2.
Feger M, Hase P, Zhang B, Hirche F, Glosse P, Lang F, Föller M., Free PMC Article | 02/2/2019 |
| VEGF and TGFB2 are upregulated in femoral bone during fracture healing following implantation with coated titanium screws. | Role of Vascular Endothelial Growth Factor and Transforming Growth Factor-β2 in Rat Bone Tissue after Bone Fracture and Placement of Titanium Implants with Bioactive Bioresorbable Coatings.
Kalinichenko SG, Matveeva NY, Kostiv RE, Puz' AV. | 07/22/2017 |
| structural changes in site-specific airways, along with the temporal and spatial expression of transforming growth factor (TGF)-beta in the lungs of male spontaneously hypertensive rats exposed to tobacco smoke, were characterized. | Temporal and Spatial Expression of Transforming Growth Factor-β after Airway Remodeling to Tobacco Smoke in Rats.
Hoang LL, Nguyen YP, Aspeé R, Bolton SJ, Shen YH, Wang L, Kenyon NJ, Smiley-Jewell S, Pinkerton KE., Free PMC Article | 07/1/2017 |
| Diminished collagen synthesis in folliculostellate cell-deficient cell aggregates was partially recovered by TGFbeta2. TGFbeta2-mediated folliculostellate cell-pericyte interaction appears to be essential for collagen synthesis in anterior pituitary. | Folliculostellate cell interacts with pericyte via TGFβ2 in rat anterior pituitary.
Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kouki T, Kikuchi M, Yashiro T. | 06/10/2017 |
| miR-378a expression is associated with its methylation status in TGF-beta1-treated cells, and epigenetically-regulated miR-378a inhibits TGF-beta1-induced hepatic stellate cells activation, at least in part, via TGF-beta2. | The Epigenetically-Regulated microRNA-378a Targets TGF-β2 in TGF-β1-Treated Hepatic Stellate Cells.
Yu F, Yang J, Huang K, Pan X, Chen B, Dong P, Zheng J. | 02/18/2017 |
| Hepatic TGFB2 gene expression was up-regulated in liver of bile duct ligation model of liver fibrosis. | Liver fibrosis in bile duct-ligated rats correlates with increased hepatic IL-17 and TGF-β2 expression.
Zepeda-Morales AS, Del Toro-Arreola S, García-Benavides L, Bastidas-Ramírez BE, Fafutis-Morris M, Pereira-Suárez AL, Bueno-Topete MR. | 01/28/2017 |
| TGFbeta2 regulates hypothalamic TRH expression through TIEG1 during fetal development. | TGFβ2 regulates hypothalamic Trh expression through the TGFβ inducible early gene-1 (TIEG1) during fetal development.
Martínez-Armenta M, Díaz de León-Guerrero S, Catalán A, Alvarez-Arellano L, Uribe RM, Subramaniam M, Charli JL, Pérez-Martínez L., Free PMC Article | 08/15/2015 |
| These study results suggest that HR controls Tgf-b2 expression via regulation of miR-31, thus causing abnormal hair cycle in Hr(Hp)/Hr(Hp) mice. | Hairless Up-Regulates Tgf-β2 Expression via Down-Regulation of miR-31 in the Skin of "Hairpoor" (HrHp) Mice.
Kim BK, Yoon SK. | 08/8/2015 |
| Data suggest that Muller cells release TGF-beta2, inhibiting the proliferation of retinal endothelial cells via activation of Smad2/Smad3 and attenuation of ERK signaling | Müller glial cells inhibit proliferation of retinal endothelial cells via TGF-β2 and Smad signaling.
Yafai Y, Iandiev I, Lange J, Unterlauft JD, Wiedemann P, Bringmann A, Reichenbach A, Eichler W. | 03/21/2015 |
| Transforming growth factor-beta2 and -beta3 potently decreased basal Sema3A expression; the maximum effect was at very low levels and completely cancelled the activities of Fibroblast Growth Factor 2 and Hepatocyte Growth Factor to upregulate Sema3A. | Growth factor regulation of neural chemorepellent Sema3A expression in satellite cell cultures.
Do MK, Sato Y, Shimizu N, Suzuki T, Shono J, Mizunoya W, Nakamura M, Ikeuchi Y, Anderson JE, Tatsumi R. | 12/31/2011 |
| The expression of TGF-betas 1, 2, and 3 in different brain regions suggests that they are involved in the regulation of different neurons, and might have subtype-specific functions following ischemic attack. | Distribution of mRNAs encoding transforming growth factors-beta1, -2, and -3 in the intact rat brain and after experimentally induced focal ischemia.
Vincze C, Pál G, Wappler EA, Szabó ER, Nagy ZG, Lovas G, Dobolyi A. | 10/30/2010 |
| Hyperstimulation with exogenous hormones affects the expression of both TGF-beta(1) and TGF-beta(2), which may contribute to the disruption of the endometrial environment required for successful embryo implantation. | The effect of hyperstimulation on transforming growth factor beta(1) and beta(2) in the rat uterus: possible consequences for embryo implantation.
Jovanović A, Kramer B. | 04/12/2010 |
| Data show that with the help of negative regulators TGF-beta and FasL, the high levels of IL-1alpha and IL-6 expressions were observed in the early stages of the infection, and decreased gradually in the later weeks both in vitro and in vivo. | Expression of IL-1alpha, IL-6, TGF-beta, FasL and ZNF265 during sertoli cell infection by ureaplasma urealyticum.
Li R, Xi Y, Liu X, Chen G, Wang B, Jiang L, Li W., Free PMC Article | 01/21/2010 |
| TGF-beta2 and TGF-beta3 induced a dose-dependant increase of apoptosis in cultured stromal cells. | Transforming growth factor beta isoforms regulation of Akt activity and XIAP levels in rat endometrium during estrous cycle, in a model of pseudopregnancy and in cultured decidual cells.
Caron PL, Fréchette-Frigon G, Shooner C, Leblanc V, Asselin E., Free PMC Article | 01/21/2010 |
| These results show that elevated expression of TSP-1 and TGF-beta can be detected in the injured segment of the spinal cord 12 and 24 h after injury. Thus, TSP-1 and TGF-beta may have a role in SCI. | The role of thrombospondin-1 and transforming growth factor-beta after spinal cord injury in the rat.
Wang X, Chen W, Liu W, Wu J, Shao Y, Zhang X. | 01/21/2010 |
| TGF-beta2 is an essential neuroprotective factor released by microglia in its culture medium that, to be fully effective, requires the concomitant presence of other factor(s) of low molecular weight. | Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2.
Polazzi E, Altamira LE, Eleuteri S, Barbaro R, Casadio C, Contestabile A, Monti B. | 01/21/2010 |
| The renoprotective effect of AM might be related to inhibition of myofibroblast activation, inducing of HGF and reducing of TGF-beta1 expression. | Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction.
Zuo C, Xie XS, Qiu HY, Deng Y, Zhu D, Fan JM., Free PMC Article | 01/21/2010 |
| immunolocalization of transforming growth factor beta (TGF-beta2) in rat thymic stromal cells and thymocytes: TGF-beta2 may play an important role in the organization or development of thymocytes in the late stages of thymopoiesis | Immunolocalization of TGF-beta2 in the rat thymus during late stages of prenatal development.
Sonmez MF, Colakoglu N, Kukner A, Ozan E, Dabak DO. | 01/21/2010 |
| Ischemia-reperfusion injury of peripheral nerves caused by various reasons affects the levels of TGF beta1 and activin A but not TGF beta2 | Effects of peripheral nerve ischemia-reperfusion model on serum cytokine levels.
Bağdatoğlu OT, Polat G, Bağdatoğlu C, Atik U. | 01/21/2010 |
| The role transforming growth factor beta (TGFb) isoforms TGFb1, TGFb2 and TGFb3 have in the regulation of embryonic gonadal development was investigated. | Transforming growth factor beta (TGFbeta1, TGFbeta2 and TGFbeta3) null-mutant phenotypes in embryonic gonadal development.
Memon MA, Anway MD, Covert TR, Uzumcu M, Skinner MK., Free PMC Article | 01/21/2010 |
| TGF-beta1 and TGF-beta 2 mRNA, but not TGF-beta3, is increased at 4 and 12 weeks in experimental diabetic peripheral neuropathy. | Transforming growth factor-beta induces cellular injury in experimental diabetic neuropathy.
Anjaneyulu M, Berent-Spillson A, Inoue T, Choi J, Cherian K, Russell JW., Free PMC Article | 01/21/2010 |