| Associations of cold-inducible RNA-binding protein with bacterial load, proinflammatory cytokines and mortality from pneumonia. | Associations of cold-inducible RNA-binding protein with bacterial load, proinflammatory cytokines and mortality from pneumonia.
Guo Q, Li HY, Zeng C, Lü ZD, Jiang M., Free PMC Article | 09/17/2024 |
| Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats. | Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats.
Zhang J, Liu T, Wei Y, Peng J, Zeng G, Zhong P., Free PMC Article | 04/1/2024 |
| Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1. | Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1.
Liu J, Ke X, Wang L, Zhang Y, Yang J., Free PMC Article | 10/9/2021 |
| Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels. | Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels.
Xie D, Geng L, Wang S, Xiong K, Zhao T, Wang G, Feng Z, Lv F, Wang C, Liang D, Shi D, Ma X, Liu Y, Yang J, Zhang C, Chen YH. | 06/19/2021 |
| Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase. | Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase.
Xie D, Geng L, Xiong K, Zhao T, Wang S, Xue J, Wang C, Wang G, Feng Z, Zhou H, Li Y, Li L, Liu Y, Xue Z, Yang J, Ma H, Liang D, Chen YH. | 05/22/2021 |
| CIRBP Ameliorates Neuronal Amyloid Toxicity via Antioxidative and Antiapoptotic Pathways in Primary Cortical Neurons. | CIRBP Ameliorates Neuronal Amyloid Toxicity via Antioxidative and Antiapoptotic Pathways in Primary Cortical Neurons.
Su F, Yang S, Wang H, Qiao Z, Zhao H, Qu Z., Free PMC Article | 11/21/2020 |
| Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration. | Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration.
Li Z, Zhang S, Li J, Zeng H, Wang Y, Huang Y. | 09/26/2020 |
| Enhanced cold-inducible RNA-binding protein in microglia aggravates neuronal injury by promoting the release of proinflammatory cytokines, which might be mediated through Brd2-NF-kappaB signals during deep hypothermic circulatory arrest. | A novel target to reduce microglial inflammation and neuronal damage after deep hypothermic circulatory arrest.
Liu M, Li Y, Gao S, Yan S, Zhang Q, Liu G, Ji B. | 06/27/2020 |
| cold temperature can induce an airway inflammatory response and excess mucus production via a CIRP-mediated increase in mRNA stability and protein translation | Cold-inducible RNA-binding protein mediates airway inflammation and mucus hypersecretion through a post-transcriptional regulatory mechanism under cold stress.
Juan Y, Haiqiao W, Xie W, Huaping H, Zhong H, Xiangdong Z, Kolosov VP, Perelman JM. | 11/26/2017 |
| therapeutic hypothermia exerts an important neuroprotective effects by up-regulating CIRP expression. | Therapeutic Hypothermia Enhances Cold-Inducible RNA-Binding Protein Expression and Inhibits Mitochondrial Apoptosis in a Rat Model of Cardiac Arrest.
Wu L, Sun HL, Gao Y, Hui KL, Xu MM, Zhong H, Duan ML. | 07/15/2017 |
| In human abdominal aortic aneurysm (AAA) tissue, Cold-inducible RNA-binding protein (CIRP) exhibited a 5.6-fold and 93% increase in mRNA and protein expression, respectively. In a rat AAA model, CIRP was upregulated significantly in a time-dependent manner in the serum and AAA tissue. | Cold-inducible RNA-binding protein plays a central role in the pathogenesis of abdominal aortic aneurysm in a murine experimental model.
Li G, Yang L, Yuan H, Liu Y, He Y, Wu X, Jin X. | 06/24/2017 |
| role in establishment of cold adaptation | Effects of Mild Chronic Intermittent Cold Exposure on Rat Organs.
Wang X, Che H, Zhang W, Wang J, Ke T, Cao R, Meng S, Li D, Weiming O, Chen J, Luo W., Free PMC Article | 07/2/2016 |
| CIRP modulates cardiac repolarization by negatively adjusting the expression and function of transient outward potassium channels. | Cold-Inducible RNA-Binding Protein Regulates Cardiac Repolarization by Targeting Transient Outward Potassium Channels.
Li J, Xie D, Huang J, Lv F, Shi D, Liu Y, Lin L, Geng L, Wu Y, Liang D, Chen YH. | 07/25/2015 |
| In animal models of hemorrhage and sepsis, CIRP is upregulated in the heart and liver and released into the circulation. In macrophages under hypoxic stress, CIRP translocates from the nucleus to the cytosol and is released. | Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis.
Qiang X, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, Fujita J, Nicastro J, Coppa GF, Tracey KJ, Wang P., Free PMC Article | 01/25/2014 |
| The induction of Cirbp protein in cortical neurons under hypothermia inhibited H2O2-induced neuronal apoptosis. | Cold-inducible RNA binding protein inhibits H₂O₂-induced apoptosis in rat cortical neurons.
Li S, Zhang Z, Xue J, Liu A, Zhang H. | 05/11/2013 |
| The analysis did not reveal any correlation between the three metabolic parameters and CIRP mRNA expression induced by hypothermia. | Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain.
Liu A, Zhang Z, Li A, Xue J. | 11/6/2010 |