| CAPG interference induces apoptosis and ferroptosis in colorectal cancer cells through the P53 pathway. | CAPG interference induces apoptosis and ferroptosis in colorectal cancer cells through the P53 pathway.
Zhao Y, Ma R, Wang C, Hu R, Wu W, Sun X, Chen B, Zhang W, Chen Y, Zhou J, Yuan P. | 09/20/2023 |
| CAPG facilitates diffuse large B-cell lymphoma cell progression through PI3K/AKT signaling pathway. | CAPG facilitates diffuse large B-cell lymphoma cell progression through PI3K/AKT signaling pathway.
Wang G, Liu H, An L, Hou S, Zhang Q. | 11/19/2022 |
| The Association Between Gelsolin-like Actin-capping Protein (CapG) Overexpression and Bladder Cancer Prognosis. | The Association Between Gelsolin-like Actin-capping Protein (CapG) Overexpression and Bladder Cancer Prognosis.
Bahrami S, Gheysarzadeh A, Sotoudeh M, Bandehpour M, Khabazian R, Zali H, Hedayati M, Basiri A, Kazemi B. | 10/2/2021 |
| The migration behavior of human glioblastoma cells is influenced by the redox-sensitive human macrophage capping protein CAPG. | The migration behavior of human glioblastoma cells is influenced by the redox-sensitive human macrophage capping protein CAPG.
Prescher N, Hänsch S, Knobbe-Thomsen CB, Stühler K, Poschmann G. | 07/3/2021 |
| Oncogenic potential of macrophagecapping protein in clear cell renal cell carcinoma. | Oncogenic potential of macrophage‑capping protein in clear cell renal cell carcinoma.
Chen ZF, Huang ZH, Chen SJ, Jiang YD, Qin ZK, Zheng SB, Chen T., Free PMC Article | 05/8/2021 |
| The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies? | The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?
Tinning H, Taylor A, Wang D, Constantinides B, Sutton R, Oikonomou G, Velazquez MA, Thompson P, Treumann A, O'Connell MJ, Forde N. | 02/27/2021 |
| CapG promotes resistance to paclitaxel in breast cancer through transactivation of PIK3R1/P50. | CapG promotes resistance to paclitaxel in breast cancer through transactivation of PIK3R1/P50.
Chi Y, Xue J, Huang S, Xiu B, Su Y, Wang W, Guo R, Wang L, Li L, Shao Z, Jin W, Wu Z, Wu J., Free PMC Article | 10/24/2020 |
| CAPG competes with the transcriptional repressor arginine methyltransferase 5 (PRMT5) for binding to the STC-1 promoter. | CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.
Huang S, Chi Y, Qin Y, Wang Z, Xiu B, Su Y, Guo R, Guo L, Sun H, Zeng C, Zhou S, Hu X, Liu S, Shao Z, Wu Z, Jin W, Wu J., Free PMC Article | 04/13/2019 |
| Study suggested that CapG could be used as a biomarker for metastatic CRC in the clinical specimens. Moreover, our in vitro study demonstrated that CapG might contribute on tumor metastasis in human CRCs. | Capping Actin Protein Overexpression in Human Colorectal Carcinoma and Its Contributed Tumor Migration.
Tsai TJ, Lim YP, Chao WY, Chen CC, Chen YJ, Lin CY, Lee YR., Free PMC Article | 12/22/2018 |
| Results revealed that CapG is a novel independent prognostic predictor for glioma patients and highlight a key role of CapG in proliferation and metastasis of glioma. | Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Yun DP, Wang YQ, Meng DL, Ji YY, Chen JX, Chen HY, Lu DR., Free PMC Article | 08/11/2018 |
| it is demonstrated that CapG is expressed in the cytoplasm and could be used as a prognostic or diagnostic biomarker for mHCC in clinical specimens | Gelsolin-like Actin-capping Protein (CapG) Overexpression in the Cytoplasm of Human Hepatocellular Carcinoma, Associated with Cellular Invasion, Migration and Tumor Prognosis.
Tsai TJ, Chao WY, Chen CC, Chen YJ, Lin CY, Lee YR. | 08/4/2018 |
| The combination of CTNB1, XPO2, and CAPG achieved 95% sensitivity and 96% specificity for the discrimination of these subtypes. We developed two uterine aspirate-based signatures to diagnose Endometrial cancer and classify tumors in the most prevalent histologic subtypes. This will improve diagnosis and assist in the prediction of the optimal surgical treatment | Targeted Proteomics Identifies Proteomic Signatures in Liquid Biopsies of the Endometrium to Diagnose Endometrial Cancer and Assist in the Prediction of the Optimal Surgical Treatment.
Martinez-Garcia E, Lesur A, Devis L, Cabrera S, Matias-Guiu X, Hirschfeld M, Asberger J, van Oostrum J, Casares de Cal MLÁ, Gómez-Tato A, Reventos J, Domon B, Colas E, Gil-Moreno A. | 07/28/2018 |
| Overexpression of CAPG is associated with glioma. | An integrated transcriptomic and computational analysis for biomarker identification in human glioma.
Xing W, Zeng C. | 02/18/2017 |
| On the basis of these results, we propose a model in which dynamic vimentin filaments target CARMIL2 to critical membrane-associated locations, where CARMIL2 regulates CP, and thus actin assembly, to create cell protrusions | CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation.
Lanier MH, Kim T, Cooper JA., Free PMC Article | 10/1/2016 |
| The composite biomarker, CAPG and GIPC1 in primary breast tumors, predicted disease outcomes and benefit from zoledronate and may facilitate patient selection for adjuvant bisphosphonate treatment. | CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment.
Westbrook JA, Cairns DA, Peng J, Speirs V, Hanby AM, Holen I, Wood SL, Ottewell PD, Marshall H, Banks RE, Selby PJ, Coleman RE, Brown JE., Free PMC Article | 05/14/2016 |
| A single nucleotide polymorphism rs6886 inside the CapG gene was identified, affecting a CapG phosphorylation site and thus potentially modifying CapG function. | Macrophage capping protein CapG is a putative oncogene involved in migration and invasiveness in ovarian carcinoma.
Glaser J, Neumann MH, Mei Q, Betz B, Seier N, Beyer I, Fehm T, Neubauer H, Niederacher D, Fleisch MC., Free PMC Article | 02/14/2015 |
| CapG was up-regulated in the tumor tissues of patients with lymph node metastasis (LNM), whereas it showed an equivalent expression level between non-tumor and tumor tissues of patients without LNM. | Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer.
Ichikawa H, Kanda T, Kosugi S, Kawachi Y, Sasaki H, Wakai T, Kondo T. | 02/22/2014 |
| CapG is involved in the process of metastasis by promoting the invasiveness of tumor cells. | Proteomic identification of the macrophage-capping protein as a protein contributing to the malignant features of hepatocellular carcinoma.
Kimura K, Ojima H, Kubota D, Sakumoto M, Nakamura Y, Tomonaga T, Kosuge T, Kondo T. | 07/6/2013 |
| CapG was identified as a novel candidate biomarker to predict response to gemcitabine treatment and survival in cholangiocarcinoma. | Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma.
Morofuji N, Ojima H, Onaya H, Okusaka T, Shimada K, Sakamoto Y, Esaki M, Nara S, Kosuge T, Asahina D, Ushigome M, Hiraoka N, Nagino M, Kondo T. | 05/26/2012 |
| Expression of CapG, gelsolin, and P-gp was found to be associated with an increased risk of death from non-small cell lung cancer. | Prognostic evaluation of CapG, gelsolin, P-gp, GSTP1, and Topo-II proteins in non-small cell lung cancer.
Zhu WY, Hunag YY, Liu XG, He JY, Chen DD, Zeng F, Zhou JH, Zhang YK. | 05/5/2012 |
| These results suggest that overexpression of CapG may be associated with progression of lung adenocarcinoma. | Overexpression of gelsolin-like actin-capping protein is associated with progression of lung adenocarcinoma.
Shao F, Zhang R, Don L, Ying K. | 04/14/2012 |
| strong down-regulation of MCK activity contributes to F-actin instability and induces post-translational modification of alphaB-crystallin and desmin | Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy.
Diguet N, Mallat Y, Ladouce R, Clodic G, Prola A, Tritsch E, Blanc J, Larcher JC, Delcayre C, Samuel JL, Friguet B, Bolbach G, Li Z, Mericskay M., Free PMC Article | 12/10/2011 |
| CapG was upregulated in the stroma cells of nasopharyngeal carcinoma (NPC) compared with normal nasopharyngeal epithelial tissues. CapG possibly plays a role in the complex interaction between NPC cells and the surrounding host tissue. | Proteomic analysis of the stroma-related proteins in nasopharyngeal carcinoma and normal nasopharyngeal epithelial tissues.
Li MX, Xiao ZQ, Chen YH, Peng F, Li C, Zhang PF, Li MY, Li F, Duan CJ, Li DJ, Yao HX, Chen ZC. | 06/14/2010 |
| Proteomic study of macrophages exposed to oxLDL identifies a CAPG polymorphism associated with carotid atherosclerosis. | Proteomic study of macrophages exposed to oxLDL identifies a CAPG polymorphism associated with carotid atherosclerosis.
Burillo E, Recalde D, Jarauta E, Fiddyment S, Garcia-Otin AL, Mateo-Gallego R, Cenarro A, Civeira F. | 01/25/2010 |
| Hypoxia-inducible factor 1alpha up-regulated CapG protein expression under normoxia. Knockdown of HIF-1alpha expression in hPASMCs also inhibited hypoxia-induced CapG up-regulation. | Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
Zhang R, Zhou L, Li Q, Liu J, Yao W, Wan H. | 01/21/2010 |