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    AXIN2 axin 2 [ Homo sapiens (human) ]

    Gene ID: 8313, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    What could be the role of genetic tests and machine learning of AXIN2 variant dominance in non-syndromic hypodontia? A case-control study in orthodontically treated patients.

    What could be the role of genetic tests and machine learning of AXIN2 variant dominance in non-syndromic hypodontia? A case-control study in orthodontically treated patients.
    Alhazmi N, Alaqla A, Almuzzaini B, Aldrees M, Alnaqa G, Almasoud F, Aldibasi O, Alshamlan H., Free PMC Article

    08/30/2024
    Axin2 depletion in macrophages alleviated senescence and increased immune response after myocardial infarction.

    Axin2 depletion in macrophages alleviated senescence and increased immune response after myocardial infarction.
    Zheng Y, Wang Y, Qi B, Gao W, Liu Y, Li T.

    02/26/2024
    JNK2 Promotes Progression of Esophageal Squamous Cell Carcinoma via Inhibiting Axin2.

    JNK2 Promotes Progression of Esophageal Squamous Cell Carcinoma via Inhibiting Axin2.
    Wang L, Guo M, Gao L, Liu K, Bai J, Liu Z.

    01/7/2024
    Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.

    Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
    Cao W, Dai S, Ruan W, Long T, Zeng Z, Lei S., Free PMC Article

    09/1/2023
    ALKBH5 Drives Immune Suppression Via Targeting AXIN2 to Promote Colorectal Cancer and Is a Target for Boosting Immunotherapy.

    ALKBH5 Drives Immune Suppression Via Targeting AXIN2 to Promote Colorectal Cancer and Is a Target for Boosting Immunotherapy.
    Zhai J, Chen H, Wong CC, Peng Y, Gou H, Zhang J, Pan Y, Chen D, Lin Y, Wang S, Kang W, To KF, Chen Z, Nie Y, He HH, Sung JJ, Yu J.

    07/25/2023
    AXIN2-related oligodontia-colorectal cancer syndrome with cleft palate as a possible new feature.

    AXIN2-related oligodontia-colorectal cancer syndrome with cleft palate as a possible new feature.
    Roht L, Hyldebrandt HK, Stormorken AT, Nordgarden H, Sijmons RH, Bos DK, Riegert-Johnson D, Mantia-Macklin S, Ilves P, Muru K, Wojcik MH, Kahre T, Õunap K., Free PMC Article

    06/19/2023
    Axin2 coupled excessive Wnt-glycolysis signaling mediates social defect in autism spectrum disorders.

    Axin2 coupled excessive Wnt-glycolysis signaling mediates social defect in autism spectrum disorders.
    Wang M, Xian P, Zheng W, Li Z, Chen A, Xiao H, Xu C, Wang F, Mao H, Meng H, Zhao Y, Luo C, Wang Y, Wu S., Free PMC Article

    06/13/2023
    Implications of Axis Inhibition Protein 2 in Breast Cancer Progression.

    Implications of Axis Inhibition Protein 2 in Breast Cancer Progression.
    Ahn SY, Jo CH., Free PMC Article

    03/14/2023
    AXIN2 germline testing in a French cohort validates pathogenic variants as a rare cause of predisposition to colorectal polyposis and cancer.

    AXIN2 germline testing in a French cohort validates pathogenic variants as a rare cause of predisposition to colorectal polyposis and cancer.
    Leclerc J, Beaumont M, Vibert R, Pinson S, Vermaut C, Flament C, Lovecchio T, Delattre L, Demay C, Coulet F, Guillerm E, Hamzaoui N, Benusiglio PR, Brahimi A, Cornelis F, Delhomelle H, Fert-Ferrer S, Fournier BPJ, Hovnanian A, Legrand C, Lortholary A, Malka D, Petit F, Saurin JC, Lejeune S, Colas C, Buisine MP., Free PMC Article

    02/15/2023
    Immunohistochemical expression of Axin-2, as an implication of the role of stem cell in scar pathogenesis and prognosis.

    Immunohistochemical expression of Axin-2, as an implication of the role of stem cell in scar pathogenesis and prognosis.
    Bazid HAS, Samaka RM, Mousa MEA, Seleit I.

    01/11/2023
    Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer.

    Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer.
    Chan JM, Clendenning M, Joseland S, Georgeson P, Mahmood K, Walker R, Como J, Joo JE, Preston S, Hutchinson RA, Pope BJ, Metz A, Beard C, Purvis R, Arnold J, Vijay V, Konycheva G, Atkinson N, Parry S, Jenkins MA, Macrae FA, Rosty C, Winship IM, Buchanan DD.

    11/12/2022
    Genotypes and Haplotypes in the AXIN2 and TCF7L2 Genes are Associated With Susceptibility and With Clinicopathological Characteristics in Breast Cancer Patients.

    Genotypes and Haplotypes in the AXIN2 and TCF7L2 Genes are Associated With Susceptibility and With Clinicopathological Characteristics in Breast Cancer Patients.
    Rosales-Reynoso MA, Rosas-Enríquez V, Saucedo-Sariñana AM, Pérez-Coria M, Gallegos-Arreola MP, Salas-González E, Barros-Núñez P, Juárez-Vázquez CI, Flores-Martínez SE, Sánchez-Corona J., Free PMC Article

    08/27/2022
    miRNA-222-3p enhances the proliferation and suppresses the apoptosis of acute myeloid leukemia cells by targeting Axin2 and modulating the Wnt/beta-catenin pathway.

    miRNA-222-3p enhances the proliferation and suppresses the apoptosis of acute myeloid leukemia cells by targeting Axin2 and modulating the Wnt/β-catenin pathway.
    Liu Z, Zhong L, Dan W, Chu X, Liu C, Luo X, Zhang Z, Lu Y, Wan P, Wang X, Liu B.

    07/30/2022
    miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR.

    miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR.
    Lukosevicius R, Juzenas S, Salteniene V, Kulokiene U, Arstikyte J, Hemmrich-Stanisak G, Franke A, Link A, Ruzgys P, Satkauskas S, Pauzas H, Latkauskas T, Kiudelis G, Balaguer F, Kupcinskas J, Skieceviciene J., Free PMC Article

    03/19/2022
    The nonredundant nature of the Axin2 regulatory network in the canonical Wnt signaling pathway.

    The nonredundant nature of the Axin2 regulatory network in the canonical Wnt signaling pathway.
    Moshkovsky AR, Kirschner MW., Free PMC Article

    03/19/2022
    Galphai2-induced conductin/axin2 condensates inhibit Wnt/beta-catenin signaling and suppress cancer growth.

    Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth.
    Miete C, Solis GP, Koval A, Brückner M, Katanaev VL, Behrens J, Bernkopf DB., Free PMC Article

    02/26/2022
    Association of AXIN2 s2240308 C>T, rs1133683 C>T, rs7224837 A>G Polymorphisms with Susceptibility to Breast Cancer.

    Association of AXIN2 s2240308 C>T, rs1133683 C>T, rs7224837 A>G Polymorphisms with Susceptibility to Breast Cancer.
    Sayad S, Abdi-Gamsae M, Jafari-Nedooshan J, Farbod M, Dastgheib SA, Karimi-Zarchi M, Asadian F, Neamatzadeh H., Free PMC Article

    01/22/2022
    ETS like-1 protein ELK1-induced lncRNA LINC01638 accelerates the progression of papillary thyroid cancer by regulating Axin2 through Wnt/beta-catenin signaling pathway.

    ETS like-1 protein ELK1-induced lncRNA LINC01638 accelerates the progression of papillary thyroid cancer by regulating Axin2 through Wnt/β-catenin signaling pathway.
    Lv P, Xue Y., Free PMC Article

    12/18/2021
    Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.

    Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.
    Wang W, Liu P, Lavrijsen M, Li S, Zhang R, Li S, van de Geer WS, van de Werken HJG, Peppelenbosch MP, Smits R., Free PMC Article

    10/30/2021
    HNRNPU-AS1 Regulates Cell Proliferation and Apoptosis via the MicroRNA 205-5p/AXIN2 Axis and Wnt/beta-Catenin Signaling Pathway in Cervical Cancer.

    HNRNPU-AS1 Regulates Cell Proliferation and Apoptosis via the MicroRNA 205-5p/AXIN2 Axis and Wnt/β-Catenin Signaling Pathway in Cervical Cancer.
    Niu Z, Wang F, Lv S, Lv Y, Liu M, Fu L, Yao Y, Wang L, Lin W, Yuan F., Free PMC Article

    10/16/2021
    The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions.

    The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions.
    Gavagan M, Fagnan E, Speltz EB, Zalatan JG., Free PMC Article

    07/31/2021
    Human fibroblast-derived extracellular vesicles promote hair growth in cultured human hair follicles.

    Human fibroblast-derived extracellular vesicles promote hair growth in cultured human hair follicles.
    Rajendran RL, Gangadaran P, Kwack MH, Oh JM, Hong CM, Sung YK, Lee J, Ahn BC.

    07/24/2021
    New insights of the correlation between AXIN2 polymorphism and cancer risk and susceptibility: evidence from 72 studies.

    New insights of the correlation between AXIN2 polymorphism and cancer risk and susceptibility: evidence from 72 studies.
    Li X, Li Y, Liu G, Wu W., Free PMC Article

    05/15/2021
    GLI1 and AXIN2 Are Distinctive Markers of Human Calvarial Mesenchymal Stromal Cells in Nonsyndromic Craniosynostosis.

    GLI1 and AXIN2 Are Distinctive Markers of Human Calvarial Mesenchymal Stromal Cells in Nonsyndromic Craniosynostosis.
    Di Pietro L, Barba M, Prampolini C, Ceccariglia S, Frassanito P, Vita A, Guadagni E, Bonvissuto D, Massimi L, Tamburrini G, Parolini O, Lattanzi W., Free PMC Article

    02/13/2021
    Significant Associations between AXIN1 rs1805105, rs12921862, rs370681 Haplotypes and Variant Genotypes of AXIN2 rs2240308 with Risk of Congenital Heart Defects.

    Significant Associations between AXIN1 rs1805105, rs12921862, rs370681 Haplotypes and Variant Genotypes of AXIN2 rs2240308 with Risk of Congenital Heart Defects.
    Crauciuc GA, Iancu M, Olah P, Tripon F, Anciuc M, Gozar L, Togănel R, Bănescu C., Free PMC Article

    01/16/2021
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