| Activation loop phosphorylaton of a non-RD receptor kinase initiates plant innate immune signaling. | Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling.
Bender KW, Couto D, Kadota Y, Macho AP, Sklenar J, Derbyshire P, Bjornson M, DeFalco TA, Petriello A, Font Farre M, Schwessinger B, Ntoukakis V, Stransfeld L, Jones AME, Menke FLH, Zipfel C., Free PMC Article | 01/15/2022 |
| expression in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen-fixing rhizobial symbiosis | Expression of the Arabidopsis thaliana immune receptor EFR in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen-fixing rhizobial symbiosis.
Pfeilmeier S, George J, Morel A, Roy S, Smoker M, Stransfeld L, Downie JA, Peeters N, Malone JG, Zipfel C., Free PMC Article | 05/25/2019 |
| These findings demonstrate the mechanistic basis of signal transduction from EFR to phytohormones, mediated through a EFR-BIK1-WRKY axis. | The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity.
Lal NK, Nagalakshmi U, Hurlburt NK, Flores R, Bak A, Sone P, Ma X, Song G, Walley J, Shan L, He P, Casteel C, Fisher AJ, Dinesh-Kumar SP., Free PMC Article | 09/22/2018 |
| transgenic rice plants (Oryza sativa L. ssp. japonica cv. Zhonghua 17) and cell cultures with constitutive expression of AtEFR were developed to investigate whether AtEFR senses EF-Tu and thus enhances bacterial resistance in the monocot plants. | Enhancement of innate immune system in monocot rice by transferring the dicotyledonous elongation factor Tu receptor EFR.
Lu F, Wang H, Wang S, Jiang W, Shan C, Li B, Yang J, Zhang S, Sun W. | 04/2/2016 |
| When challenged with the cereal bacterial pathogen Pseudomonas syringae pv. oryzae, transgenic EFR wheat lines had reduced lesion size and bacterial multiplication. | Arabidopsis EF-Tu receptor enhances bacterial disease resistance in transgenic wheat.
Schoonbeek HJ, Wang HH, Stefanato FL, Craze M, Bowden S, Wallington E, Zipfel C, Ridout CJ. | 01/16/2016 |
| study first mapped the phosphorylation patterns of BAK1 associated with four RLK partners (BRI1, FLS2, EFR and BIK1 | Assessment of BAK1 activity in different plant receptor-like kinase complexes by quantitative profiling of phosphorylation patterns.
Wang Y, Li Z, Liu D, Xu J, Wei X, Yan L, Yang C, Lou Z, Shui W. | 04/4/2015 |
| OST3/6 deficiency affects the biogenesis of EFR, resulting in the impairment of innate immunity. OST3/6 plays an important role for abiotic stress tolerance and for the functionality of the endoglucanase KOR1 essential for cellulose biosynthesis. | Specialized roles of the conserved subunit OST3/6 of the oligosaccharyltransferase complex in innate immunity and tolerance to abiotic stresses.
Farid A, Malinovsky FG, Veit C, Schoberer J, Zipfel C, Strasser R., Free PMC Article | 12/28/2013 |
| A knockout mutant showed reduced downy mildew infection, but susceptibility was fully restored through complementation of the mutation, suggesting that the (malectin like)LRR-RLK contributes to disease. | An Arabidopsis (malectin-like) leucine-rich repeat receptor-like kinase contributes to downy mildew disease.
Hok S, Danchin EG, Allasia V, Panabières F, Attard A, Keller H. | 02/4/2012 |
| The effects of protein domain mutations on the binding properties of EFR and FLS2 are reported. | Chimeric receptors of the Arabidopsis thaliana pattern recognition receptors EFR and FLS2.
Albert M, Felix G., Free PMC Article | 09/3/2011 |
| The ligand-induced heteromerization of EFR and FLS2 with BAK1 is independent of kinase activity in planta. | Phosphorylation-dependent differential regulation of plant growth, cell death, and innate immunity by the regulatory receptor-like kinase BAK1.
Schwessinger B, Roux M, Kadota Y, Ntoukakis V, Sklenar J, Jones A, Zipfel C., Free PMC Article | 08/27/2011 |
| Activation of FLS2 and EFR by bacterial peptide elicitors led to calcium-associated plasma membrane anion channel opening. | Early signaling through the Arabidopsis pattern recognition receptors FLS2 and EFR involves Ca-associated opening of plasma membrane anion channels.
Jeworutzki E, Roelfsema MR, Anschütz U, Krol E, Elzenga JT, Felix G, Boller T, Hedrich R, Becker D. | 09/20/2010 |
| EFR(N143Q) lacking a single conserved N-glycosylation site from the EFR ectodomain accumulated to reduced levels and lost the ability to bind its ligand and to mediate elf18-elicited oxidative burst. | Pattern recognition receptors require N-glycosylation to mediate plant immunity.
Häweker H, Rips S, Koiwa H, Salomon S, Saijo Y, Chinchilla D, Robatzek S, von Schaewen A., Free PMC Article | 05/31/2010 |
| These results show that the plasma membrane pattern-recognition receptor EFR requires the endoplasmic reticulum complex SDF2-ERdj3B-BiP for its proper accumulation. | Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity.
Nekrasov V, Li J, Batoux M, Roux M, Chu ZH, Lacombe S, Rougon A, Bittel P, Kiss-Papp M, Chinchilla D, van Esse HP, Jorda L, Schwessinger B, Nicaise V, Thomma BP, Molina A, Jones JD, Zipfel C., Free PMC Article | 01/21/2010 |