| This study's results demonstrate a role for UGT85A3 and UGT73C1 as a link between CUP-SHAPED COTYLEDON 1 (CUC1) and CUC2, and cytokinin (CK) homeostasis, and highlight the importance of CUCs and CKs in the determination of seed yield. | CUP-SHAPED COTYLEDON1 (CUC1) and CUC2 regulate cytokinin homeostasis to determine ovule number in Arabidopsis.
Cucinotta M, Manrique S, Cuesta C, Benkova E, Novak O, Colombo L., Free PMC Article | 10/19/2019 |
| we show that CUC2 acts as a trigger to promote growth through the activation of three functional relays. In particular, we show that KLUH acts downstream of CUC2 to modulate auxin response and that expressing KLUH can compensate for deficient CUC2 expression during tooth growth. | Dissecting the pathways coordinating patterning and growth by plant boundary domains.
Maugarny-Calès A, Cortizo M, Adroher B, Borrega N, Gonçalves B, Brunoud G, Vernoux T, Arnaud N, Laufs P., Free PMC Article | 03/16/2019 |
| Genetic analysis established that SVR9/SVR9-LIKE1 (SVR9L1)-mediated leaf margin development is dependent on CUP-SHAPED COTYLEDON2 (CUC2) activities and is independent of their roles in chloroplast development. | Chloroplast Translation Initiation Factors Regulate Leaf Variegation and Development.
Zheng M, Liu X, Liang S, Fu S, Qi Y, Zhao J, Shao J, An L, Yu F., Free PMC Article | 10/14/2017 |
| The cuc2 cuc3 double mutant displays irregular phyllotaxis in the mature shoot but not in the shoot apex, thus showing a post-meristematic effect of the mutations on phyllotaxis. | The CUP-SHAPED COTYLEDON2 and 3 genes have a post-meristematic effect on Arabidopsis thaliana phyllotaxis.
Burian A, Raczyńska-Szajgin M, Borowska-Wykręt D, Piatek A, Aida M, Kwiatkowska D., Free PMC Article | 05/21/2016 |
| PLT3, PLT5, and PLT7 additionally regulate and require the shoot-promoting factor CUP-SHAPED COTYLEDON2 (CUC2) to complete the shoot-formation program. | PLETHORA Genes Control Regeneration by a Two-Step Mechanism.
Kareem A, Durgaprasad K, Sugimoto K, Du Y, Pulianmackal AJ, Trivedi ZB, Abhayadev PV, Pinon V, Meyerowitz EM, Scheres B, Prasad K., Free PMC Article | 02/13/2016 |
| cuc1 grf1/2/3, cuc2 grf1/2/3, and cuc3 grf1/2/3 quadruple mutants showed dramatic increases in cotyledon fusion as well as floral organ fusion. | Genetic interaction between GROWTH-REGULATING FACTOR and CUP-SHAPED COTYLEDON in organ separation.
Lee BH, Jeon JO, Lee MM, Kim JH., Free PMC Article | 01/2/2016 |
| Cup-shaped cotyledon (CUC)1, CUC2, and AINTEGUMENTA (ANT) have additive effects on ovule primordia formation. | An integrative model of the control of ovule primordia formation.
Galbiati F, Sinha Roy D, Simonini S, Cucinotta M, Ceccato L, Cuesta C, Simaskova M, Benkova E, Kamiuchi Y, Aida M, Weijers D, Simon R, Masiero S, Colombo L. | 05/31/2014 |
| CUC2 is a predictive marker for the acquisition of root explant competence for root and shoot organogenesis. | CUC2 as an early marker for regeneration competence in Arabidopsis root explants.
Motte H, Verstraeten I, Werbrouck S, Geelen D. | 11/17/2012 |
| SPT negatively regulates CUC1 and CUC2 expression in the apical part of the gynoecium. | Interactions of CUP-SHAPED COTYLEDON and SPATULA genes control carpel margin development in Arabidopsis thaliana.
Nahar MA, Ishida T, Smyth DR, Tasaka M, Aida M., Free PMC Article | 09/29/2012 |
| DPA4 expression domains overlap with those of the known leaf shape regulator CUP-SHAPED COTYLEDON 2 (CUC2) and we provide evidence that DPA4 negatively regulates CUC2 expression independently of MIR164A, an established regulator of CUC2 | Development-related PcG target in the apex 4 controls leaf margin architecture in Arabidopsis thaliana.
Engelhorn J, Reimer JJ, Leuz I, Göbel U, Huettel B, Farrona S, Turck F. | 09/8/2012 |
| CUC2 and CUC3 are expressed in leaf primordia and are required for wild-type serration. CUC1 and CUC2 resulted from duplications of a unique ancestral gene and show different patterns of evolution. | Evolution and diverse roles of the CUP-SHAPED COTYLEDON genes in Arabidopsis leaf development.
Hasson A, Plessis A, Blein T, Adroher B, Grigg S, Tsiantis M, Boudaoud A, Damerval C, Laufs P., Free PMC Article | 07/2/2011 |
| CUC2 promotes outgrowth of leaf teeth via cell division. | Mechanisms of leaf tooth formation in Arabidopsis.
Kawamura E, Horiguchi G, Tsukaya H. | 09/20/2010 |
| CUC2 and CUC3 expression mediated by AHK2 and AHK3 signaling may play roles in regulation of flower development. | Cytokinin overproduction-caused alteration of flower development is partially mediated by CUC2 and CUC3 in Arabidopsis.
Li XG, Su YH, Zhao XY, Li W, Gao XQ, Zhang XS. | 01/21/2010 |
| miRNA164 and CUC2 form a central regulatory module that acts as a governor of lateral organ patterning and expansion. | A microRNA-transcription factor module regulates lateral organ size and patterning in Arabidopsis.
Larue CT, Wen J, Walker JC. | 01/21/2010 |
| Regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. | Interplay of miR164, CUP-SHAPED COTYLEDON genes and LATERAL SUPPRESSOR controls axillary meristem formation in Arabidopsis thaliana.
Raman S, Greb T, Peaucelle A, Blein T, Laufs P, Theres K. | 01/21/2010 |
| The molecular basis for the activity of the protein. | The NAC domain mediates functional specificity of CUP-SHAPED COTYLEDON proteins.
Taoka K, Yanagimoto Y, Daimon Y, Hibara K, Aida M, Tasaka M. | 01/21/2010 |
| The balance between coexpressed CUC2 and MIR164A then determines the extent of serration. | The balance between the MIR164A and CUC2 genes controls leaf margin serration in Arabidopsis.
Nikovics K, Blein T, Peaucelle A, Ishida T, Morin H, Aida M, Laufs P., Free PMC Article | 01/21/2010 |
| We show here that plants expressing a miR164-resistant CUP-SHAPED COTYLEDON2 (CUC2) gene have an abnormal phyllotactic pattern in the fully grown stem, despite the pattern of organ initiation by the meristem being normal. | Plants expressing a miR164-resistant CUC2 gene reveal the importance of post-meristematic maintenance of phyllotaxy in Arabidopsis.
Peaucelle A, Morin H, Traas J, Laufs P. | 01/21/2010 |