LEAFY and APETALA1 down-regulate ZINC FINGER PROTEIN 1 and 8 to release their repression on class B and C floral homeotic genes. | LEAFY and APETALA1 down-regulate ZINC FINGER PROTEIN 1 and 8 to release their repression on class B and C floral homeotic genes. Hu T, Li X, Du L, Manuela D, Xu M., Free PMC Article | 05/30/2023 |
The LEAFY floral regulator displays pioneer transcription factor properties. | The LEAFY floral regulator displays pioneer transcription factor properties. Lai X, Blanc-Mathieu R, GrandVuillemin L, Huang Y, Stigliani A, Lucas J, Thévenon E, Loue-Manifel J, Turchi L, Daher H, Brun-Hernandez E, Vachon G, Latrasse D, Benhamed M, Dumas R, Zubieta C, Parcy F. | 01/8/2022 |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate. | LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate. Jin R, Klasfeld S, Zhu Y, Fernandez Garcia M, Xiao J, Han SK, Konkol A, Wagner D., Free PMC Article | 02/6/2021 |
LFY activity is fully dependent on BOP2 as well as on CUL3A and B to regulate target genes such as APETALA1 and to induce ectopic flower formation. | LEAFY activity is post-transcriptionally regulated by BLADE ON PETIOLE2 and CULLIN3 in Arabidopsis. Chahtane H, Zhang B, Norberg M, LeMasson M, Thévenon E, Bakó L, Benlloch R, Holmlund M, Parcy F, Nilsson O, Vachon G. | 10/5/2019 |
LFY and AP1 are conserved floral regulators that act nonredundantly in C. hirsuta, such that LFY has more obvious roles in floral and leaf development in C. hirsuta than in A. thaliana. | Conservation vs divergence in LEAFY and APETALA1 functions between Arabidopsis thaliana and Cardamine hirsuta. Monniaux M, McKim SM, Cartolano M, Thévenon E, Parcy F, Tsiantis M, Hay A. | 05/26/2018 |
LFY and AP1/CAL act as part of an incoherent feed-forward loop, a network motif where two interconnected pathways or transcription factors act in opposite directions on a target gene, to control the establishment of a stable developmental program for the formation of flowers. | Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOWER during Floral Initiation. Goslin K, Zheng B, Serrano-Mislata A, Rae L, Ryan PT, Kwaśniewska K, Thomson B, Ó'Maoiléidigh DS, Madueño F, Wellmer F, Graciet E., Free PMC Article | 01/20/2018 |
WRKY71 activity hastens flowering via the direct activation of FT and LFY. | WRKY71 accelerates flowering via the direct activation of FLOWERING LOCUS T and LEAFY in Arabidopsis thaliana. Yu Y, Liu Z, Wang L, Kim SG, Seo PJ, Qiao M, Wang N, Li S, Cao X, Park CM, Xiang F. | 04/8/2017 |
data suggest that transcriptional regulation of LFY at the chromatin level by PKL may at least partially account for the late-flowering phenotype of pkl mutants | CHD3 chromatin-remodeling factor PICKLE regulates floral transition partially via modulating LEAFY expression at the chromatin level in Arabidopsis. Fu X, Li C, Liang Q, Zhou Y, He H, Fan LM. | 03/11/2017 |
ANT and AIL6 directly induce LFY expression in response to auxin to promote the onset of flower formation. | AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Yamaguchi N, Jeong CW, Nole-Wilson S, Krizek BA, Wagner D., Free PMC Article | 09/24/2016 |
A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor. | A SAM oligomerization domain shapes the genomic binding landscape of the LEAFY transcription factor. Sayou C, Nanao MH, Jamin M, Posé D, Thévenon E, Grégoire L, Tichtinsky G, Denay G, Ott F, Peirats Llobet M, Schmid M, Dumas R, Parcy F., Free PMC Article | 09/10/2016 |
Data suggest that helix-turn-helix transcription factor LEAFY (LFY) and the MADS box transcription factor APETALA1 (AP1)together orchestrate the switch to flower formation and morphogenesis by altering transcriptional programs. | Transcriptional programs regulated by both LEAFY and APETALA1 at the time of flower formation. Winter CM, Yamaguchi N, Wu MF, Wagner D., Free PMC Article | 05/21/2016 |
The ULT1 and LFY pathways act separately in regulating identity and determinacy at the floral meristem. In particular, they independently induce AG expression in the centre of the flower to terminate meristem activity. | ULTRAPETALA1 and LEAFY pathways function independently in specifying identity and determinacy at the Arabidopsis floral meristem. Engelhorn J, Moreau F, Fletcher JC, Carles CC., Free PMC Article | 07/25/2015 |
A LFY allele with reduced floral function revealed its ability to stimulate axillary meristem growth. This role requires the ability of LFY to bind DNA, and is mediated by direct induction of REGULATOR OF AXILLARY MERISTEMS1 (RAX1) by LFY. | A variant of LEAFY reveals its capacity to stimulate meristem development by inducing RAX1. Chahtane H, Vachon G, Le Masson M, Thévenon E, Périgon S, Mihajlovic N, Kalinina A, Michard R, Moyroud E, Monniaux M, Sayou C, Grbic V, Parcy F, Tichtinsky G. | 01/4/2014 |
LEAFY controls auxin response pathways in floral primordium formation. | LEAFY controls auxin response pathways in floral primordium formation. Li W, Zhou Y, Liu X, Yu P, Cohen JD, Meyerowitz EM., Free PMC Article | 10/26/2013 |
these three transcription factors LFY, ANT and AIL6/PLT3 are redundantly required for flower primordium initiation. | A molecular framework for auxin-mediated initiation of flower primordia. Yamaguchi N, Wu MF, Winter CM, Berns MC, Nole-Wilson S, Yamaguchi A, Coupland G, Krizek BA, Wagner D. | 05/25/2013 |
must act in complexes that contain at least two LFY molecules; the N-terminus is essential for stabilization | A conserved domain in the N-terminus is important for LEAFY dimerization and function in Arabidopsis thaliana. Siriwardana NS, Lamb RS. | 01/12/2013 |
Studies indicate that LEAFY is a master regulator of flowering. | The poetry of reproduction: the role of LEAFY in Arabidopsis thaliana flower formation. Siriwardana NS, Lamb RS. | 09/29/2012 |
LFY activity affects adaxial pedicel identity and cell elongation. LFY mutation suppresses the crm1 pedicel length and orientation phenotypes. | LEAFY controls Arabidopsis pedicel length and orientation by affecting adaxial-abaxial cell fate. Yamaguchi N, Yamaguchi A, Abe M, Wagner D, Komeda Y. | 07/21/2012 |
The SWI2/SNF2 ATPases physically interact with two direct transcriptional activators of class B and class C gene expression, LEAFY (LFY) and SEPALLATA3 (SEP3). | SWI2/SNF2 chromatin remodeling ATPases overcome polycomb repression and control floral organ identity with the LEAFY and SEPALLATA3 transcription factors. Wu MF, Sang Y, Bezhani S, Yamaguchi N, Han SK, Li Z, Su Y, Slewinski TL, Wagner D., Free PMC Article | 05/12/2012 |
LEAFY binding site is essential for proper photoperiodic activation of APETALA1 | Integrating long-day flowering signals: a LEAFY binding site is essential for proper photoperiodic activation of APETALA1. Benlloch R, Kim MC, Sayou C, Thévenon E, Parcy F, Nilsson O. | 03/10/2012 |
A biophysical model describing LFY DNA binding specificity in vitro was built that accurately predicts in vivo LFY binding sites in the Arabidopsis thaliana genome. | Prediction of regulatory interactions from genome sequences using a biophysical model for the Arabidopsis LEAFY transcription factor. Moyroud E, Minguet EG, Ott F, Yant L, Posé D, Monniaux M, Blanchet S, Bastien O, Thévenon E, Weigel D, Schmid M, Parcy F., Free PMC Article | 09/24/2011 |
Data show that the direct LEAFY target LATE MERISTEM IDENTITY2 (LMI2) has a role in the meristem identity transition, and acts together with LEAFY to activate APETALA1. | LATE MERISTEM IDENTITY2 acts together with LEAFY to activate APETALA1. Pastore JJ, Limpuangthip A, Yamaguchi N, Wu MF, Sang Y, Han SK, Malaspina L, Chavdaroff N, Yamaguchi A, Wagner D., Free PMC Article | 09/24/2011 |
The motif analyses reveal a possible mechanism for stage-specific LFY recruitment and suggest a role for LFY in overcoming polycomb repression. | LEAFY target genes reveal floral regulatory logic, cis motifs, and a link to biotic stimulus response. Winter CM, Austin RS, Blanvillain-Baufumé S, Reback MA, Monniaux M, Wu MF, Sang Y, Yamaguchi A, Yamaguchi N, Parker JE, Parcy F, Jensen ST, Li H, Wagner D. | 06/18/2011 |
Data show that LEAFY, FRUITFULL, and APETALA1 are directly activated by the microRNA-targeted transcription factor SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 3 (SPL3) to control the timing of flower formation. | The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1. Yamaguchi A, Wu MF, Yang L, Wu G, Poethig RS, Wagner D., Free PMC Article | 01/21/2010 |
LFY and AGL15 are involved in the regulation of AtMYB17 in early inflorescence development and seed germination. | Characterization of Arabidopsis MYB transcription factor gene AtMYB17 and its possible regulation by LEAFY and AGL15. Zhang Y, Cao G, Qu LJ, Gu H. | 01/21/2010 |