| Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1. | Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1.
Osakabe A, Takizawa Y, Horikoshi N, Hatazawa S, Negishi L, Sato S, Berger F, Kakutani T, Kurumizaka H., Free PMC Article | 08/8/2024 |
| Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Liu Y, Zhang Z, Hu H, Chen W, Zhang F, Wang Q, Wang C, Yan K, Du J. | 03/25/2024 |
| Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Lee SC, Adams DW, Ipsaro JJ, Cahn J, Lynn J, Kim HS, Berube B, Major V, Calarco JP, LeBlanc C, Bhattacharjee S, Ramu U, Grimanelli D, Jacob Y, Voigt P, Joshua-Tor L, Martienssen RA., Free PMC Article | 11/1/2023 |
| DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis. | DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis.
Zhou J, Lei X, Shafiq S, Zhang W, Li Q, Li K, Zhu J, Dong Z, He XJ, Sun Q., Free PMC Article | 08/17/2023 |
| DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis. | DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis.
Lee S, Choi J, Park J, Hong CP, Choi D, Han S, Choi K, Roh TY, Hwang D, Hwang I., Free PMC Article | 05/22/2023 |
| Loss of chromatin remodeler DDM1 causes segregation distortion in Arabidopsis thaliana. | Loss of chromatin remodeler DDM1 causes segregation distortion in Arabidopsis thaliana.
Ali S, Zhang T, Lambing C, Wang W, Zhang P, Xie L, Wang J, Khan N, Zhang Q. | 10/30/2021 |
| The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W. | The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W.
Osakabe A, Jamge B, Axelsson E, Montgomery SA, Akimcheva S, Kuehn AL, Pisupati R, Lorković ZJ, Yelagandula R, Kakutani T, Berger F. | 06/26/2021 |
| These results suggest that DDM1 is involved in the homology directed repair such as SSA and HR, probably by modifying chromatin structure. | Mutation in DDM1 inhibits the homology directed repair of double strand breaks.
Choi SH, Ryu TH, Kim JI, Lee S, Lee SS, Kim JH., Free PMC Article | 11/9/2019 |
| Data show that chromatin remodeling 1 (DDM1) is required for telomere length maintenance. | DDM1 guards against telomere truncation in Arabidopsis.
Xie X, Shippen DE., Free PMC Article | 09/8/2018 |
| Here, the authors show that genetic inactivation of a single DDM1/Lsh family nucleosome remodeler biases methylation toward inter-nucleosomal linker DNA in Arabidopsis thaliana and mouse. The results indicate that in the absence of remodeling, nucleosomes are strong barriers to DNA methyltransferases. | DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes.
Lyons DB, Zilberman D., Free PMC Article | 07/21/2018 |
| Hybrids with a mutation in decrease in DNA methylation 1 (DDM1) showed a decreased heterosis level. | Role of DNA methylation in hybrid vigor in Arabidopsis thaliana.
Kawanabe T, Ishikura S, Miyaji N, Sasaki T, Wu LM, Itabashi E, Takada S, Shimizu M, Takasaki-Yasuda T, Osabe K, Peacock WJ, Dennis ES, Fujimoto R., Free PMC Article | 02/3/2018 |
| nucleosome remodeler DDM1-mediated repression of aberrant gene transcriptional read-through | DNA methylation signature of intergenic region involves in nucleosome remodeler DDM1-mediated repression of aberrant gene transcriptional read-through.
Yan X, Dong X, Liu L, Yang Y, Lai J, Guo Y. | 10/28/2017 |
| The results suggest that dedifferentiation is associated with Tag1 activation and that CMT3 rather than DDM1 plays a central role in restraining Tag1 activation via inducing gene body DNA methylation. | Activation of Tag1 transposable elements in Arabidopsis dedifferentiating cells and their regulation by CHROMOMETHYLASE 3-mediated CHG methylation.
Khan A, Yadav NS, Morgenstern Y, Zemach A, Grafi G. | 06/3/2017 |
| SWI2/SNF2 chromatin remodeling proteins such as DRD1 and DDM1 may influence leaf senescence possibly via epigenetic regulation | A Mutation in Plant-Specific SWI2/SNF2-Like Chromatin-Remodeling Proteins, DRD1 and DDM1, Delays Leaf Senescence in Arabidopsis thaliana.
Cho EJ, Choi SH, Kim JH, Kim JE, Lee MH, Chung BY, Woo HR, Kim JH., Free PMC Article | 07/30/2016 |
| when chromosomes with reduced DNA methylation were introduced from a ddm1 mutant into a DDM1 wild-type background, the ddm1-derived chromosomes also induced analogous de novo accumulation of DNA methylation in trans | Genome-wide negative feedback drives transgenerational DNA methylation dynamics in Arabidopsis.
Ito T, Tarutani Y, To TK, Kassam M, Duvernois-Berthet E, Cortijo S, Takashima K, Saze H, Toyoda A, Fujiyama A, Colot V, Kakutani T., Free PMC Article | 04/16/2016 |
| Data indicate function of DNA methylation1 (DDM1) and Morpheus' Molecule1 (MOM1) in rapid resetting of stress induced epigenetic states, and therefore also in preventing their mitotic propagation and transgenerational inheritance. | Identification of genes preventing transgenerational transmission of stress-induced epigenetic states.
Iwasaki M, Paszkowski J., Free PMC Article | 10/4/2014 |
| Results indicate that DDM1 provides DNA methyltransferases access to H1-containing heterochromatin to allow stable silencing of transposable elements in cooperation with the small-RNA-directed DNA methylation pathway. | The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to access H1-containing heterochromatin.
Zemach A, Kim MY, Hsieh PH, Coleman-Derr D, Eshed-Williams L, Thao K, Harmer SL, Zilberman D., Free PMC Article | 06/1/2013 |
| Heterozygous ddm1/DDM1 plants are more sensitive to stress and have more severe changes in methylation than homozygous ddm1/ddm1 plants. | ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair.
Yao Y, Bilichak A, Golubov A, Kovalchuk I. | 12/22/2012 |
| RNA-directed DNA methylation is dispensable for ddm1-induced BONSAI methylation. | RNAi-independent de novo DNA methylation revealed in Arabidopsis mutants of chromatin remodeling gene DDM1.
Sasaki T, Kobayashi A, Saze H, Kakutani T. | 09/15/2012 |
| Data show that DDM1 loss of function may trigger changes that enhance meiotic recombination in euchromatin regions but are not sufficient to induce the same events in heterochromatic segments. | Deficiency in DNA methylation increases meiotic crossover rates in euchromatic but not in heterochromatic regions in Arabidopsis.
Melamed-Bessudo C, Levy AA., Free PMC Article | 07/14/2012 |
| DDM1 and siRNA-dependent silencing are overlapping processes that both repress aberrant 5S rDNA transcription and contribute to the heterochromatic state of 5S rDNA arrays | Heterochromatic siRNAs and DDM1 independently silence aberrant 5S rDNA transcripts in Arabidopsis.
Blevins T, Pontes O, Pikaard CS, Meins F Jr., Free PMC Article | 01/21/2010 |
| control DNA methylation in Arabidopsis thaliana.[review] | [Mechanisms to control DNA methylation in Arabidopsis thaliana].
Sasaki T, Saze H, Kakutani T. | 01/21/2010 |
| ddm1 mutation induces various types of developmental abnormalities through de-repression of transposons and repeats | Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1.
Saze H, Kakutani T., Free PMC Article | 01/21/2010 |
| Maternal and paternal genomes play distinct roles in the regulation of seed size in Arabidopsis, as determined by mutation status of DDM1 and MET1. | Regulation of seed size by hypomethylation of maternal and paternal genomes.
Xiao W, Brown RC, Lemmon BE, Harada JJ, Goldberg RB, Fischer RL., Free PMC Article | 01/21/2010 |