Canonical transcriptional gene silencing may contribute to long-term heat response and recovery through MOM1. | Canonical transcriptional gene silencing may contribute to long-term heat response and recovery through MOM1. Torres JR, Botto JF, Sanchez DH. | 12/6/2023 |
The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation. | The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation. Li Z, Wang M, Zhong Z, Gallego-Bartolomé J, Feng S, Jami-Alahmadi Y, Wang X, Wohlschlegel J, Bischof S, Long JA, Jacobsen SE., Free PMC Article | 07/17/2023 |
The SUMO interaction motif responsible for the interaction of MOM1 with SUMO. | Exploring potential roles for the interaction of MOM1 with SUMO and the SUMO E3 ligase-like protein PIAL2 in transcriptional silencing. Zhao QY, He XJ., Free PMC Article | 02/16/2019 |
study suggests that PIAL1 and PIAl2 act as components of the MOM1-containing complex to mediate transcriptional silencing at heterochromatin regions. | The SUMO E3 Ligase-Like Proteins PIAL1 and PIAL2 Interact with MOM1 and Form a Novel Complex Required for Transcriptional Silencing. Han YF, Zhao QY, Dang LL, Luo YX, Chen SS, Shao CR, Huang HW, Li YQ, Li L, Cai T, Chen S, He XJ., Free PMC Article | 11/11/2017 |
Data indicate function of DNA methylation1 (DDM1) and Morpheus' Molecule1 (MOM1) in rapid resetting of stress induced epigenetic states, and therefore also in preventing their mitotic propagation and transgenerational inheritance. | Identification of genes preventing transgenerational transmission of stress-induced epigenetic states. Iwasaki M, Paszkowski J., Free PMC Article | 10/4/2014 |
synergistic transcriptional regulation in the mom1/atmorc6 double mutant, indicating that these epigenetic regulators act mainly in different silencing pathways, both independently of DNA methylation | Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Moissiard G, Bischof S, Husmann D, Pastor WA, Hale CJ, Yen L, Stroud H, Papikian A, Vashisht AA, Wohlschlegel JA, Jacobsen SE., Free PMC Article | 07/19/2014 |
These results reveal a surprising separation of epigenetic activities that enable the single, large MOM1 protein to coordinate cooperating mechanisms of epigenetic regulation | Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1. Nishimura T, Molinard G, Petty TJ, Broger L, Gabus C, Halazonetis TD, Thore S, Paszkowski J., Free PMC Article | 05/19/2012 |
the degree of contribution of MOM1 to maintenance of the silent states varies in different loci, and other silencing machineries, including those in the RNA-directed DNA methylation pathway, interact genetically with MOM1 | Epigenetic silencing of endogenous repetitive sequences by MORPHEUS' MOLECULE1 in Arabidopsis thaliana. Habu Y. | 07/2/2011 |
MOM1 plays a role in preventing aberrant RNA transcriptional read-through. | MORPHEUS' MOLECULE1 is required to prevent aberrant RNA transcriptional read-through in Arabidopsis. Zhou Y, Zhang J, Lin H, Guo G, Guo Y., Free PMC Article | 02/26/2011 |
Crystals of Morpheus' molecule 1 belonged to the trigonal space group P3(1)21 (or P3(2)21), with unit-cell parameters a=85.64, c=292.74 A. Structure determination is ongoing | Expression, crystallization and preliminary X-ray diffraction analysis of the CMM2 region of the Arabidopsis thaliana Morpheus' molecule 1 protein. Petty TJ, Nishimura T, Emamzadah S, Gabus C, Paszkowski J, Halazonetis TD, Thore S., Free PMC Article | 11/27/2010 |
Pol-V is required for MOM1-mediated suppression of transcription at a subset of its chromosomal targets. | MOM1 and Pol-IV/V interactions regulate the intensity and specificity of transcriptional gene silencing. Yokthongwattana C, Bucher E, Caikovski M, Vaillant I, Nicolet J, Mittelsten Scheid O, Paszkowski J., Free PMC Article | 02/8/2010 |
Less than 13% of MOM1 sequence is necessary and sufficient for its transcriptional gene silencing function. | Divergent evolution of CHD3 proteins resulted in MOM1 refining epigenetic control in vascular plants. Caikovski M, Yokthongwattana C, Habu Y, Nishimura T, Mathieu O, Paszkowski J., Free PMC Article | 01/21/2010 |