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    FLP Duplicated homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837997, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FOUR LIPS plays a role in meristemoid-to-GMC fate transition during stomatal development in Arabidopsis.

    FOUR LIPS plays a role in meristemoid-to-GMC fate transition during stomatal development in Arabidopsis.
    Li P, Chen L, Gu X, Zhao M, Wang W, Hou S.

    04/12/2023
    FLP and MYB88 inhibit the production of nonstomatal epidermal cells largely in a growth-condition-dependent manner.

    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Yang M.

    09/9/2017
    Both flp and myb88 genes were expressed in many, previously unreported locations, consistent with the possibility of additional functions for FLP and MYB88. Moreover, expression domains especially of FLP display sharp cutoffs or boundaries.

    The FOUR LIPS and MYB88 transcription factor genes are widely expressed in Arabidopsis thaliana during development.
    Lei Q, Lee E, Keerthisinghe S, Lai L, Li M, Lucas JR, Wen X, Ren X, Sack FD.

    06/28/2016
    FLP and MYB88 expression specifically determines the temporal-spatial patterns of PIN3 and PIN7 transcription that are closely associated with their preferential functions during root responses to gravity.

    Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis root gravitropism.
    Wang HZ, Yang KZ, Zou JJ, Zhu LL, Xie ZD, Morita MT, Tasaka M, Friml J, Grotewold E, Beeckman T, Vanneste S, Sack F, Le J., Free PMC Article

    05/14/2016
    ARF7 and FLP transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation.

    A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development.
    Chen Q, Liu Y, Maere S, Lee E, Van Isterdael G, Xie Z, Xuan W, Lucas J, Vassileva V, Kitakura S, Marhavý P, Wabnik K, Geldner N, Benková E, Le J, Fukaki H, Grotewold E, Li C, Friml J, Sack F, Beeckman T, Vanneste S., Free PMC Article

    05/14/2016
    Data indicate that MYB transcription factor FOUR LIPS (FLP) and bHLH transcription factor FAMA complement respective mutant phenotypes.

    Deep functional redundancy between FAMA and FOUR LIPS in stomatal development.
    Lee E, Lucas JR, Sack FD.

    02/21/2015
    Data indicate that bHLH transcription factor FAMA and MYB transcription factor FOUR LIPS (FLP) genes stabilize guard cell fate.

    Arabidopsis guard cell integrity involves the epigenetic stabilization of the FLP and FAMA transcription factor genes.
    Lee E, Lucas JR, Goodrich J, Sack FD.

    02/21/2015
    FLP and MYB88 restrict the G1/S transition during stomatal formation.

    FOUR LIPS and MYB88 conditionally restrict the G1/S transition during stomatal formation.
    Lee E, Liu X, Eglit Y, Sack F., Free PMC Article

    06/28/2014
    FLP and MYB88 are important regulators of entry into megasporogenesis, and probably act via the regulation of cell cycle genes.

    The R2R3 MYB transcription factors FOUR LIPS and MYB88 regulate female reproductive development.
    Makkena S, Lee E, Sack FD, Lamb RS., Free PMC Article

    01/4/2014
    flp-1 myb88 double mutant plants show enhanced sensitivity to drought and salt stress.

    Role of the stomatal development regulators FLP/MYB88 in abiotic stress responses.
    Xie Z, Li D, Wang L, Sack FD, Grotewold E.

    04/2/2011
    targets. FLP recognizes a distinct cis-regulatory element that overlaps with that of the cell cycle activator E2F-DP in the CDKB1;1 promoter, suggesting that these MYBs may also modulate E2F-DP pathways

    Regulation of cell proliferation in the stomatal lineage by the Arabidopsis MYB FOUR LIPS via direct targeting of core cell cycle genes.
    Xie Z, Lee E, Lucas JR, Morohashi K, Li D, Murray JA, Sack FD, Grotewold E., Free PMC Article

    01/1/2011
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