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    LHY Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839341, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Twilight length alters growth and flowering time in Arabidopsis via LHY/CCA1.

    Twilight length alters growth and flowering time in Arabidopsis via LHY/CCA1.
    Mehta D, Scandola S, Kennedy C, Lummer C, Gallo MCR, Grubb LE, Tan M, Scarpella E, Uhrig RG., Free PMC Article

    07/1/2024
    XAP5 CIRCADIAN TIMEKEEPER specifically modulates 3' splice site recognition and is important for circadian clock regulation partly by alternative splicing of LHY and TIC.

    XAP5 CIRCADIAN TIMEKEEPER specifically modulates 3' splice site recognition and is important for circadian clock regulation partly by alternative splicing of LHY and TIC.
    Liu L, Li X, Yuan L, Zhang G, Gao H, Xu X, Zhao H.

    02/12/2022
    LHY positively regulates post-penetration resistance in Arabidopsis thaliana.

    CCA1 and LHY contribute to nonhost resistance to Pyricularia oryzae (syn. Magnaporthe oryzae) in Arabidopsis thaliana.
    Yamaura S, Yamauchi Y, Makihara M, Yamashino T, Ishikawa A.

    01/18/2020
    we also found that CCA1 is required for both a short- and long-term response of the circadian oscillator to sucrose, while LHY acts to attenuate the effects of sucrose on circadian period. Together, this work highlights new pathways for how sucrose could be signaling to the oscillator and reveals further functional separation of CCA1 and LHY.

    Physiological and Genetic Dissection of Sucrose Inputs to the Arabidopsis thaliana Circadian System.
    Philippou K, Ronald J, Sánchez-Villarreal A, Davis AM, Davis SJ., Free PMC Article

    12/28/2019
    LHY promoted expression of abscissic acid (ABA)-responsive genes responsible for increased tolerance to drought and osmotic stress but alleviated the inhibitory effect of ABA on seed germination and plant growth.

    Circadian control of abscisic acid biosynthesis and signalling pathways revealed by genome-wide analysis of LHY binding targets.
    Adams S, Grundy J, Veflingstad SR, Dyer NP, Hannah MA, Ott S, Carré IA.

    09/28/2019
    Transcriptional co-regulators PRR9, PRR7 and PRR5 inhibit morning loop LHY and CCA1 expression by binding to their promoters

    A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana.
    Higham CF, Husmeier D., Free PMC Article

    03/29/2014
    Histone 3 activating marks associated with the translational start sites of CCA1/LHY and TOC1 are circadian regulated.

    Circadian clock regulates dynamic chromatin modifications associated with Arabidopsis CCA1/LHY and TOC1 transcriptional rhythms.
    Hemmes H, Henriques R, Jang IC, Kim S, Chua NH., Free PMC Article

    09/7/2013
    Rhythmic expression of LHY under light-dark cycling conditions correlates with histone modification.

    Rhythmic oscillation of histone acetylation and methylation at the Arabidopsis central clock loci.
    Song HR, Noh YS., Free PMC Article

    04/20/2013
    Our computational analysis suggests that TOC1 is a repressor of the morning genes Late Elongated Hypocotyl and Circadian Clock Associated1 rather than an activator as first conceived.

    The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops.
    Pokhilko A, Fernández AP, Edwards KD, Southern MM, Halliday KJ, Millar AJ., Free PMC Article

    05/26/2012
    Functional interactions between the clock proteins LHY and CCA1 and the photoreceptor PhyB control organ elongation and flowering time.

    Suppression of late-flowering and semi-dwarf phenotypes in the Arabidopsis clock mutant lhy-12;cca1-101 by phyB under continuous light.
    Miyata K, Calviño M, Oda AO, Sugiyama H, Mizoguchi T., Free PMC Article

    03/31/2012
    Interaction of Arabidopsis DET1 with LHY in mediating transcriptional repression in the plant circadian clock

    Interaction of Arabidopsis DET1 with CCA1 and LHY in mediating transcriptional repression in the plant circadian clock.
    Lau OS, Huang X, Charron JB, Lee JH, Li G, Deng XW., Free PMC Article

    12/24/2011
    CCA1/LHY-mediated output from the circadian clock contributes to plant cold tolerance through regulation of the CBF cold-response pathway.

    Circadian clock-associated 1 and late elongated hypocotyl regulate expression of the C-repeat binding factor (CBF) pathway in Arabidopsis.
    Dong MA, Farré EM, Thomashow MF., Free PMC Article

    06/25/2011
    LHY/CCA1 regulates a pathway negatively controlling flowering locus T (FT), possibly via ELF3-SVP/FLC.

    Possible role of early flowering 3 (ELF3) in clock-dependent floral regulation by short vegetative phase (SVP) in Arabidopsis thaliana.
    Yoshida R, Fekih R, Fujiwara S, Oda A, Miyata K, Tomozoe Y, Nakagawa M, Niinuma K, Hayashi K, Ezura H, Coupland G, Mizoguchi T.

    06/18/2011
    Results reveal a role of PRR7 and PRR9 in regulating CCA1 and LHY activities in response to ambient temperature.

    The role of the Arabidopsis morning loop components CCA1, LHY, PRR7, and PRR9 in temperature compensation.
    Salomé PA, Weigel D, McClung CR., Free PMC Article

    04/23/2011
    LHY ubiquitination by SINAT5 was inhibited by DET1.

    Ubiquitination of LHY by SINAT5 regulates flowering time and is inhibited by DET1.
    Park BS, Eo HJ, Jang IC, Kang HG, Song JT, Seo HS.

    08/16/2010
    A conserved G-Box motif contributes to the rhythmic expression of LHY.

    Evolutionarily conserved regulatory motifs in the promoter of the Arabidopsis clock gene LATE ELONGATED HYPOCOTYL.
    Spensley M, Kim JY, Picot E, Reid J, Ott S, Helliwell C, Carré IA., Free PMC Article

    01/21/2010
    CCA1 and LHY function synergistically in regulating circadian rhythms of Arabidopsis.

    CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL function synergistically in the circadian clock of Arabidopsis.
    Lu SX, Knowles SM, Andronis C, Ong MS, Tobin EM., Free PMC Article

    01/21/2010
    CCA1 and LHY delay flowering time under continuous light by reducing the accumulation of SVP.

    Circadian clock proteins LHY and CCA1 regulate SVP protein accumulation to control flowering in Arabidopsis.
    Fujiwara S, Oda A, Yoshida R, Niinuma K, Miyata K, Tomozoe Y, Tajima T, Nakagawa M, Hayashi K, Coupland G, Mizoguchi T., Free PMC Article

    01/21/2010
    The linkages of TOC1, CCA1 and LHY genes and the canonical CO-FT flowering pathway were studied.

    Genetic linkages of the circadian clock-associated genes, TOC1, CCA1 and LHY, in the photoperiodic control of flowering time in Arabidopsis thaliana.
    Niwa Y, Ito S, Nakamichi N, Mizoguchi T, Niinuma K, Yamashino T, Mizuno T.

    01/21/2010
    Accumulation of the LHY protein in the lhy-1 mutant was altered by the det1-1 mutation and through the proteasome pathway.

    DET1 regulates the proteasomal degradation of LHY, a component of the Arabidopsis circadian clock.
    Song HR, Carré IA.

    01/21/2010
    The function of ELF3 and ELF4 in their light-regulated expression associated with CCA1, LHY, and TOC1 as part of the central oscillator of the circadian clock in Arabidopsis is reported.

    ELF4 is a phytochrome-regulated component of a negative-feedback loop involving the central oscillator components CCA1 and LHY.
    Kikis EA, Khanna R, Quail PH.

    01/21/2010
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