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    USP32 ubiquitin specific peptidase 32 [ Homo sapiens (human) ]

    Gene ID: 84669, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Furin Egress from the TGN is Regulated by Membrane-Associated RING-CH Finger (MARCHF) Proteins and Ubiquitin-Specific Protease 32 (USP32) via Nondegradable K33-Polyubiquitination.

    Furin Egress from the TGN is Regulated by Membrane-Associated RING-CH Finger (MARCHF) Proteins and Ubiquitin-Specific Protease 32 (USP32) via Nondegradable K33-Polyubiquitination.
    Su W, Ahmad I, Wu Y, Tang L, Khan I, Ye B, Liang J, Li S, Zheng YH., Free PMC Article

    10/3/2024
    High USP32 expression contributes to cancer progression and is correlated with immune infiltrates in hepatocellular carcinoma.

    High USP32 expression contributes to cancer progression and is correlated with immune infiltrates in hepatocellular carcinoma.
    Xiu M, Bao W, Wang J, Chen J, Li Y, Hai Y., Free PMC Article

    11/29/2023
    Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells.

    Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells.
    Zhang H, Tao Y, Ding X, Wang Y, Wang X., Free PMC Article

    05/13/2023
    Deubiquitylation of Rab35 by USP32 promotes the transmission of imatinib resistance by enhancing exosome secretion in gastrointestinal stromal tumours.

    Deubiquitylation of Rab35 by USP32 promotes the transmission of imatinib resistance by enhancing exosome secretion in gastrointestinal stromal tumours.
    Li C, Gao Z, Cui Z, Liu Z, Bian Y, Sun H, Wang N, He Z, Li B, Li F, Li Z, Wang L, Zhang D, Yang L, Xu Z, Xu H.

    03/21/2023
    Identification of ubiquitin-specific protease 32 as an oncogene in glioblastoma and the underlying mechanisms.

    Identification of ubiquitin-specific protease 32 as an oncogene in glioblastoma and the underlying mechanisms.
    Chen S, Chen X, Li Z, Mao J, Jiang W, Zhu Z, Li Y, Jiang Z, Zhao W, Tan G, Wang Z., Free PMC Article

    05/14/2022
    USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2.

    USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2.
    Chandrasekaran AP, Kaushal K, Park CH, Kim KS, Ramakrishna S., Free PMC Article

    02/12/2022
    USP32 promotes tumorigenesis and chemoresistance in gastric carcinoma via upregulation of SMAD2.

    USP32 promotes tumorigenesis and chemoresistance in gastric carcinoma via upregulation of SMAD2.
    Dou N, Hu Q, Li L, Wu Q, Li Y, Gao Y., Free PMC Article

    08/28/2021
    Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1.

    Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1.
    Nakae A, Kodama M, Okamoto T, Tokunaga M, Shimura H, Hashimoto K, Sawada K, Kodama T, Copeland NG, Jenkins NA, Kimura T.

    07/3/2021
    the small GTPase Rab7-the logistical centerpiece of late endosome biology-is a substrate of USP32.

    USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7.
    Sapmaz A, Berlin I, Bos E, Wijdeven RH, Janssen H, Konietzny R, Akkermans JJ, Erson-Bensan AE, Koning RI, Kessler BM, Neefjes J, Ovaa H., Free PMC Article

    05/4/2019
    USP32 silencing arrested cell cycle progression at G0/G1 phase via decreasing CDK4/Cyclin D1 complex and elevating p21.

    Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.
    Hu W, Wei H, Li K, Li P, Lin J, Feng R., Free PMC Article

    09/2/2017
    USP32 is overexpressed in breast cancer.

    USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers.
    Akhavantabasi S, Akman HB, Sapmaz A, Keller J, Petty EM, Erson AE.

    01/1/2011
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
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