| Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. | Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression.
Herrero E, Stinus S, Bellows E, Berry LK, Wood H, Thorpe PH., Free PMC Article | 07/17/2021 |
| ACE2, a transcription factor required for septum destruction after cytokinesis, is a negative regulator of ethanol tolerance. | Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES.
Luo Z, Wang L, Wang Y, Zhang W, Guo Y, Shen Y, Jiang L, Wu Q, Zhang C, Cai Y, Dai J., Free PMC Article | 12/22/2018 |
| Therefore, Ace2 and Swi5 are two negative regulators of ethanol yield during static fermentation of yeast cells, and both CTS1 and RPS4a are major effectors mediating these two transcription factors in regulating ethanol production. | The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in Saccharomyces cerevisiae.
Wu Y, Du J, Xu G, Jiang L. | 12/17/2016 |
| Data show that mutation of the Rts1 regulatory subunit of PP2A phosphatase (PP2ARts1 phosphatase) results in decreased HO endonuclease expression due to altered localization of the Ace2 transcription factor. | The Rts1 regulatory subunit of PP2A phosphatase controls expression of the HO endonuclease via localization of the Ace2 transcription factor.
Parnell EJ, Yu Y, Lucena R, Yoon Y, Bai L, Kellogg DR, Stillman DJ., Free PMC Article | 04/25/2015 |
| Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae. | Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae.
Oud B, Guadalupe-Medina V, Nijkamp JF, de Ridder D, Pronk JT, van Maris AJ, Daran JM., Free PMC Article | 01/4/2014 |
| show that Ace2 asymmetry is initiated in the elongated, but undivided, anaphase nucleus | Nuclear envelope morphology constrains diffusion and promotes asymmetric protein segregation in closed mitosis.
Boettcher B, Marquez-Lago TT, Bayer M, Weiss EL, Barral Y., Free PMC Article | 09/1/2012 |
| we discovered previously unrecognized levels of regulation of the Ace2 transcription factor and the cyclin-dependent protein kinase inhibitor Sic1 | New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1.
Cocklin R, Heyen J, Larry T, Tyers M, Goebl M., Free PMC Article | 07/16/2011 |
| Data show that Ace2's nuclear localization is maintained by continuous Cbk1 activity and that inhibition of the kinase leads to immediate loss of phosphorylation and export to the cytoplasm. | Sequential counteracting kinases restrict an asymmetric gene expression program to early G1.
Mazanka E, Weiss EL., Free PMC Article | 02/26/2011 |
| Regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. | Daughter-specific transcription factors regulate cell size control in budding yeast.
Di Talia S, Wang H, Skotheim JM, Rosebrock AP, Futcher B, Cross FR., Free PMC Article | 02/22/2010 |
| In the daughter cell nucleus Cbk1p phosphorylates the Ace2p nuclear export signal, and the phosphorylation blocks the export of Ace2p via Crm1p. | Mutations in a small region of the exportin Crm1p disrupt the daughter cell-specific nuclear localization of the transcription factor Ace2p in Saccharomyces cerevisiae.
Bourens M, Racki W, Bécam AM, Panozzo C, Boulon S, Bertrand E, Herbert CJ. | 01/21/2010 |
| the precise timing of Ace2 accumulation in the nucleus involves both a nuclear export sequence and a nuclear localization signal, whose activities are regulated by phosphorylation | Regulation of the yeast Ace2 transcription factor during the cell cycle.
Sbia M, Parnell EJ, Yu Y, Olsen AE, Kretschmann KL, Voth WP, Stillman DJ., Free PMC Article | 01/21/2010 |
| Phosphorylation of the C-terminal site of Cbk1 is regulated over the cell cycle and requires Ace2 as well as all RAM network components.Ace2 is not only a downstream target of Cbk1 but also reinforces activation of its upstream regulator. | Phosphoregulation of Cbk1 is critical for RAM network control of transcription and morphogenesis.
Jansen JM, Barry MF, Yoo CK, Weiss EL., Free PMC Article | 01/21/2010 |